Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
halogenation
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "halogenation" in MCE Product Catalog:
Cat. No.: HY-W011168
CAS No.: 13389-03-2
Research Areas:
8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H2O2-Cl --Br - system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .
Cat. No.: HY-W023557
CAS No.: 1072-87-3
Synonyms: 3-Methylmaleimide; 2-Methylmaleimide
Target:
Research Areas:
Citraconimide is a 3-methylmaleimide derivative. Citraconimide has thiol affinity and can undergo highly regioselective addition with a variety of alkyl thiols. Citraconimide derivatives show growth inhibitory activity against HeLa cells. Citraconimide can be modified by N-substitution, halogenation and other reactions for use in bioactive molecule design and drug development research .
Cat. No.: HY-N16646
CAS No.: 1622947-22-1
Target:
Cat. No.: HY-W1058183
CAS No.: 70380-30-2
Target:
Research Areas:
1-Benzyl-4-(bromomethyl)-1H-1,2,3-triazole is a bromomethyl derivative that inhibits DNA synthesis in tumor cells and promotes the release of radioactivity from labeled nucleic acids. 1-Benzyl-4-(bromomethyl)-1H-1,2,3-triazole inhibits the growth of cancer cells in vitro with an ED50 of 2 μg/mL. It can be used in cervical cancer-related research .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
