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Results for "

halogenation

" in MedChemExpress (MCE) Product Catalog:

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Natural
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1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W011168
    8-Bromo-2'-deoxyguanosine

    		Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Inflammation/Immunology Cancer
    8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H2O2-Cl --Br - system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .
    8-Bromo-2'-deoxyguanosine
  • HY-W023557
    Citraconimide

    3-Methylmaleimide; 2-Methylmaleimide

    		 Drug Intermediate Others
    Citraconimide is a 3-methylmaleimide derivative. Citraconimide has thiol affinity and can undergo highly regioselective addition with a variety of alkyl thiols. Citraconimide derivatives show growth inhibitory activity against HeLa cells. Citraconimide can be modified by N-substitution, halogenation and other reactions for use in bioactive molecule design and drug development research .
    Citraconimide
  • HY-N16646
    Micrometam A

    		Drug Derivative Infection
    Micrometam A is a phenethylamine derivative found in Micromelum falcatum. Micrometam A exhibits anti-halogenation activity with a LD50 of 18.5 μg/mL .
    Micrometam A

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