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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
244 Results for "
heterodimer
" in MedChemExpress (MCE) Product Catalog:
Products (244)
244 Results for "heterodimer" in MCE Product Catalog:
20
20 Publications Verification
Synonyms: SAH (S-Adenosylhomocysteine)
Category:
Human Gut Microbiota Metabolites Microorganisms Disease markers Metabolic Disease Amino acids Nervous System Disorder Endogenous metabolite Disease Research Fields
Target:
13
13 Cited Publications
Target:
Áreas de investigación:
CU-T12-9 is a specific TLR1/2 agonist with EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS .
10
10 Cited Publications
Referencia número: HY-17029
No. CAS: 152044-54-7
Synonyms: EPO 906; Patupilone
Epothilone B is a microtubule stabilizer (MSA) with a Ki of 0.71μM, and is a MSA with blood-brain barrier permeability. Epothilone B acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation .
9
9 Cited Publications
Referencia número: HY-D0844
No. CAS: 27025-41-8
Synonyms: L-Glutathione oxidized; GSSG; Oxiglutatione
8
8 Cited Publications
STL127705 (Compound L) is a potent Ku 70/80 heterodimer protein inhibitor with an IC50 of 3.5 μM. STL127705 interferes the binding of Ku70/80 to DNA and by inhibits the activation of the DNA-PKCS kinase. STL127705 shows antiproliferative and anticancer activity. STL127705 induces apoptosis .
6
6 Cited Publications
Synonyms: Alitretinoin
Category:
Terpenoids Diterpenoids Endogenous metabolite Disease Research Fields Inflammation/Immunology Cancer
Target:
5
5 Cited Publications
Referencia número: HY-P3229
No. CAS: 1071173-56-2
3
3 Cited Publications
Referencia número: HY-P1275
No. CAS: 910044-56-3
Target:
Áreas de investigación:
3
3 Cited Publications
Target:
Áreas de investigación:
KS15 is an inhibitor of the interactions between cryptochromes (CRYs: CRY1 and CRY2) and the CLOCK:BMAL1 heterodimer. KS15 impairs the feedback actions of CRYs on E-box-dependent transcription (EC50=4.9 μM) by CLOCK:BMAL1 heterodimer, an indispensable transcriptional regulator of the mammalian circadian clock. Anti-proliferative activity .
1
1 Cited Publications
Target:
Áreas de investigación:
CYM51010 is a biased ligand of μ-opioid receptor – δ-opioid receptor heterodimers with an EC50 of 403 nM. CYM51010 exhibits anti-nociceptive activity similar to morphine but with a decreased levels of tolerance development and withdrawal symptoms .
1
1
1
1 Cited Publications
Synonyms: NDI-034858; TAK-279
Target:
Áreas de investigación:
Zasocitinib (NDI-034858) is a TYK2 inhibitor, target TYK2 JH2 domain with binding constant Kd of <200 pM .
1
1 Cited Publications
Referencia número: HY-P700797
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NKG2C&CD94; NKG2C; CD94
1
1
1 Cited Publications
Referencia número: HY-P990203
Target:
Áreas de investigación:
1
1 Cited Publications
Referencia número: HY-P702687
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; CCND2; Cyclin-dependent kinase 6; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIRE; G1/S-specific cyclin-D2
Species:
Source:
Referencia número: HY-P99676
No. CAS: 2559704-24-2
Synonyms: SI-B001; BL-B01D1 Antibody
Target:
Áreas de investigación:
2,2′-Dipyridyl disulfide is a useful reagent for the determination of sulfhydryl groups. 2,2′-Dipyridyl disulfide is a common reagent in peptide chemistry, often used in oxidation–reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
