1. GPCR/G Protein Neuronal Signaling
  2. Opioid Receptor
  3. CYM51010

CYM51010 is a biased ligand of μ-opioid receptor – δ-opioid receptor heterodimers with an EC50 of 403 nM. CYM51010 exhibits anti-nociceptive activity similar to morphine but with a decreased levels of tolerance development and withdrawal symptoms.

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CYM51010 Chemical Structure

CYM51010 Chemical Structure

CAS No. : 1069498-96-9

Size Price Stock Quantity
5 mg USD 115 In-stock
10 mg USD 185 In-stock
25 mg USD 350 In-stock
50 mg USD 560 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

CYM51010 is a biased ligand of μ-opioid receptor – δ-opioid receptor heterodimers with an EC50 of 403 nM. CYM51010 exhibits anti-nociceptive activity similar to morphine but with a decreased levels of tolerance development and withdrawal symptoms[1].

Molecular Weight

408.53

Formula

C25H32N2O3

CAS No.
Appearance

Solid

Color

Light yellow to light brown

SMILES

O=C(C1(CCC2=CC=CC=C2)CCN(CC3=CC=C(NC(C)=O)C=C3)CC1)OCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (305.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4478 mL 12.2390 mL 24.4780 mL
5 mM 0.4896 mL 2.4478 mL 4.8956 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4478 mL 12.2390 mL 24.4780 mL 61.1950 mL
5 mM 0.4896 mL 2.4478 mL 4.8956 mL 12.2390 mL
10 mM 0.2448 mL 1.2239 mL 2.4478 mL 6.1195 mL
15 mM 0.1632 mL 0.8159 mL 1.6319 mL 4.0797 mL
20 mM 0.1224 mL 0.6120 mL 1.2239 mL 3.0598 mL
25 mM 0.0979 mL 0.4896 mL 0.9791 mL 2.4478 mL
30 mM 0.0816 mL 0.4080 mL 0.8159 mL 2.0398 mL
40 mM 0.0612 mL 0.3060 mL 0.6120 mL 1.5299 mL
50 mM 0.0490 mL 0.2448 mL 0.4896 mL 1.2239 mL
60 mM 0.0408 mL 0.2040 mL 0.4080 mL 1.0199 mL
80 mM 0.0306 mL 0.1530 mL 0.3060 mL 0.7649 mL
100 mM 0.0245 mL 0.1224 mL 0.2448 mL 0.6120 mL
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CYM51010 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CYM51010
Cat. No.:
HY-104006
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