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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
intercellular adhesion molecule-1
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "intercellular adhesion molecule-1" in MCE Product Catalog:
11
Target:
Research Areas:
Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease .
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11 Cited Publications
Cat. No.: HY-19344A
CAS No.: 1119276-80-0
Synonyms: SAR 1118 sodium; SHP-606 sodium
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Research Areas:
Lifitegrast (SAR 1118) sodium is a potent integrin antagonist. Lifitegrast sodium blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast sodium can be used for researching dry eye disease .
6
6 Cited Publications
Cat. No.: HY-P1110
CAS No.: 185413-30-3
Target:
Research Areas:
4
4 Cited Publications
Target:
Research Areas:
BIRT 377 is a potent amd orally bioavailable inhibitor of the interaction between intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1). BIRT 377 also inhibits the production of IL-2 in vivo. BIRT 377 can be used for researching inflammatory and immune disorders .
2
2 Cited Publications
Cat. No.: HY-125864B
CAS No.: 9001-32-5
Research Areas:
Murine Fibrinogen is a native fibrinogen derived from mouse plasma. Murine Fibrinogen acts as a cerebrovascular permeability enhancer. Murine Fibrinogen activates matrix metalloproteinase-9 (MMP-9), downregulates the expression of vascular endothelial cadherin (VE-cadherin), and upregulates the expression of plasmalemmal vesicle-associated protein-1 (PV-1). Murine Fibrinogen increases macromolecular leakage from pial veins, thereby disrupting the microvascular integrity of cerebral blood vessels. Murine Fibrinogen can be used in studies related to cerebrovascular dysfunction .
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1
1 Cited Publications
Cat. No.: HY-P73911
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ICAM1; Epididymis Secretory Sperm Binding Protein; intercellular adhesion molecule 1; intercellular adhesion molecule-1; CD54; Cell Surface Glycoprotein P3.58; BB2; Human Rhinovirus Receptor; Major Group Rhinovirus Receptor; CD54 Antigen; ICAM-1; P3.58; I
Cat. No.: HY-P99473
CAS No.: 1987854-08-9
Synonyms: BI-505
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RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion .
Cat. No.: HY-P99127
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Cat. No.: HY-19344R
CAS No.: 1025967-78-5
Synonyms: SAR 1118 (Standard); SHP-606 (Standard)
Target:
Research Areas:
Lifitegrast (Standard) is the analytical standard of Lifitegrast. This product is intended for research and analytical applications. Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease .
Cat. No.: HY-13412
CAS No.: 159138-81-5
Synonyms: HOE-642
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Research Areas:
Cariporide is a Na+/H+ Exchanger 1 (NHE-1) inhibitor. Cariporide inhibits the expression of monocyte endothelial cell adhesion and intercellular adhesion molecule-1 (ICAM-1) mediated by high glucose (HG) by inhibiting the activation of NHE-1 .
Cat. No.: HY-127113
CAS No.: 1541762-55-3
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Research Areas:
Q8, an effective antiangiogenic drug, is a CysLt1 antagonist (IC50 of 4.9 μM). Q8 is sufficient to reduce cellular levels of NF-κB and calpain-2 and secreted levels of the proangiogenic proteins intercellular adhesion molecule-1, vascular cell adhesion protein-1, and VEGF .
Cat. No.: HY-P5767
CAS No.: 160927-63-9
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Cat. No.: HY-P991250
Cat. No.: HY-P703752
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ICAM1; Epididymis Secretory Sperm Binding Protein; intercellular adhesion molecule 1; intercellular adhesion molecule-1; CD54; Cell Surface Glycoprotein P3.58; BB2; Human Rhinovirus Receptor; Major Group Rhinovirus Receptor; CD54 Antigen; ICAM-1; P3.58; I
Cat. No.: HY-P703780
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ICAM1; Epididymis Secretory Sperm Binding Protein; intercellular adhesion molecule 1; intercellular adhesion molecule-1; CD54; Cell Surface Glycoprotein P3.58; BB2; Human Rhinovirus Receptor; Major Group Rhinovirus Receptor; CD54 Antigen; ICAM-1; P3.58; I
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Source:
Cat. No.: HY-P73112
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ICAM1; Epididymis Secretory Sperm Binding Protein; intercellular adhesion molecule 1; intercellular adhesion molecule-1; CD54; Cell Surface Glycoprotein P3.58; BB2; Human Rhinovirus Receptor; Major Group Rhinovirus Receptor; CD54 Antigen; ICAM-1; P3.58; I
Cat. No.: HY-P73113
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ICAM1; Epididymis Secretory Sperm Binding Protein; intercellular adhesion molecule 1; intercellular adhesion molecule-1; CD54; Cell Surface Glycoprotein P3.58; BB2; Human Rhinovirus Receptor; Major Group Rhinovirus Receptor; CD54 Antigen; ICAM-1; P3.58; I
Cat. No.: HY-P73114
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ICAM1; Epididymis Secretory Sperm Binding Protein; intercellular adhesion molecule 1; intercellular adhesion molecule-1; CD54; Cell Surface Glycoprotein P3.58; BB2; Human Rhinovirus Receptor; Major Group Rhinovirus Receptor; CD54 Antigen; ICAM-1; P3.58; I
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
