159138-81-5
159138-81-5
Chemical Structure
Cariporide (mesilate)
Synonym(s): HOE-642
- CAS No.: 159138-81-5
- Formula:C13H21N3O6S2
- Molecular Weight:379.45
IUPAC Name: N-carbamimidoyl-4-isopropyl-3-(methylsulfonyl)benzamide methanesulfonate
InChIKey: FNDLQABGYJQJPH-UHFFFAOYSA-N
SMILES: O=C(NC(N)=N)C1=CC=C(C(C)C)C(S(=O)(C)=O)=C1.CS(=O)(O)=O
Biological Activity: Cariporide is a Na+/H+ Exchanger 1 (NHE-1) inhibitor. Cariporide inhibits the expression of monocyte endothelial cell adhesion and intercellular adhesion molecule-1 (ICAM-1) mediated by high glucose (HG) by inhibiting the activation of NHE-1[1].
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Cariporide (mesilate) | Cariporide is a Na+/H+ Exchanger 1 (NHE-1) inhibitor. Cariporide inhibits the expression of monocyte endothelial cell adhesion and intercellular adhesion molecule-1 (ICAM-1) mediated by high glucose (HG) by inhibiting the activation of NHE-1. | |||||||||||||||||||||
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References
Keywords
