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Bersanlimab  (Synonyms: BI-505)

Cat. No.: HY-P99473 Purity: ≥99.0%
COA

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Bersanlimab (BI-505) is a fully human monoclonal antibody that targets intercellular adhesion molecule-1 (ICAM-1 or CD54). Bersanlimab has anticancer effects.

For research use only. We do not sell to patients.

Bersanlimab Chemical Structure

Bersanlimab Chemical Structure

CAS No. : 1987854-08-9

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5 mg USD 1090 In-stock
10 mg USD 1850 In-stock
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Description

Bersanlimab (BI-505) is a fully human monoclonal antibody that targets intercellular adhesion molecule-1 (ICAM-1 or CD54). Bersanlimab has anticancer effects[1].

In Vitro

BI-505 (1 ng/mL-1000 μg/mL) dose-dependently induces programmed cell death (PCD) in ICAM-1-expressing Ramos, Raji, and Daudi lymphoma cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

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In Vivo

Bersanlimab (BI-505; 20 mg/kg; i.p.; twice-weekly; for 21 days) significantly reduceds tumor growth and prolonges animal survival[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: SCID mice injected with ARH-77 cells[1]
Dosage: 20 mg/kg
Administration: i.p.; twice-weekly; for 21 days
Result: Significantly reduced tumor growth and prolonged animal survival.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Bersanlimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: ≥99.0%

COA (231 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bersanlimab1987854-08-9BI-505BI505BI 505IntegrinICAM-1CD54anticancer effectsprogrammed cell deathInhibitorinhibitorinhibit

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