162112-37-0

RWJ 50271 Chemical Structure
162112-37-0

Chemical Structure

RWJ 50271

  • CAS No.: 162112-37-0
  • Formula:C18H17F3N4O2S
  • Molecular Weight:410.41

IUPAC Name: N-(3-hydroxypropyl)-5-methyl-1-(4-(3-(trifluoromethyl)phenyl)thiazol-2-yl)-1H-pyrazole-4-carboxamide

InChIKey: HOFGTYCLOKDAES-UHFFFAOYSA-N

SMILES: CC1=C(C(NCCCO)=O)C=NN1C2=NC(C3=CC(C(F)(F)F)=CC=C3)=CS2

Biological Activity: RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion[1].

Cat. No. Product Name Purity Description Pricing
HY-110086 		RWJ 50271 99.23% RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion.
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