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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
100 Results for "
interleukin-2
" in MedChemExpress (MCE) Product Catalog:
Products (100)
100 Results for "interleukin-2" in MCE Product Catalog:
29
24
13
13 Cited Publications
Cat. No.: HY-B0199A
CAS No.: 116680-01-4
Synonyms: RS 61443 hydrochloride; TM-MMF hydrochloride
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3
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Soquelitinib (CPI-818) is an orally active and highly selective covalent interleukin-2-inducible kinase (ITK) inhibitor. Soquelitinib is active in six different models of T cell-mediated inflammatory and immune disease, including acute and chronic asthma, pulmonary fibrosis, systemic sclerosis (scleroderma), psoriasis, and acute graft versus host disease with Th2 cytokine product inhibition. Soquelitinib increases tumor infiltration of normal CD8 + cells that possess enhanced T effector function [2] .
3
3 Cited Publications
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PRN694 is an irreversible, highly selective and potent covalent interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) dual inhibitor with IC50s of 0.3 nM and 1.4 nM, respectively. PRN694 exhibits extended target residence time on ITK and RLK, enabling durable attenuation of effector cells in vitro and in vivo .
3
1
1 Cited Publications
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(5Z,2E)-CU-3 is an isomer of CU-3 (HY-121638). CU-3 is a DGKα inhibitor with an IC50 of 0.6 μM. CU-3 competitively reduces DGKα’s affinity for ATP via binding to the enzyme’s catalytic region. CU-3 induces apoptosis in cancer cells. CU-3 promotes T-cell activation and enhances IL-2 production. CU-3 can be used for the research of hepatocellular carcinoma and cervical cancer .
1
1 Cited Publications
Cat. No.: HY-P7037AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2
1
1
1 Cited Publications
Cat. No.: HY-P70646AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin
Synonyms: CHI 621
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Infection Neurological Disease Inflammation/Immunology Cancer
Synonyms: Ro 24-7375
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Cat. No.: HY-P99728
CAS No.: 2056881-92-4
Synonyms: RG7835; RO7049665
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Cat. No.: HY-P99479
CAS No.: 1957239-90-5
Synonyms: L19-IL2
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Zinc acetate acts as an immune response modulator. Zinc acetate enhances the expression of HSP-70 mRNA. Zinc acetate restores the proliferation and cytokine production capacities of splenocytes. Zinc acetate reduces the Apoptosis level of splenocytes in endotoxemic mice. Zinc acetate increases plasma zinc levels and improves survival rates in mice with LPS-induced lethal endotoxemia. Zinc acetate induces rapid death of prostate cancer cell lines in vitro. Zinc acetate inhibits the growth of prostate cancer xenografts in SCID mice. Zinc acetate can be used in endotoxemia research [2].
Cat. No.: HY-P99877
CAS No.: 2049067-94-7
Synonyms: AMG592
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Cat. No.: HY-21293
CAS No.: 114727-43-4
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SU5201 is an inhibitor of interleukin-2 (IL-2) production .
Cat. No.: HY-149917
PROTAC ITK degrader 1 is a highly selective degrader of interleukin-2-inducible T-cell kinase (ITK; DC50=3.6 nM in vivo in mice), with good plasma exposure levels. PROTAC ITK degrader 1 induces rapid, and prolonged ITK degradation and suppresses IL-2 secretion (EC50=35.2 nM, Jurkat cells) stimulated by anti-CD3 antibodyin vivo .
Cat. No.: HY-P990086
CAS No.: 2733581-99-0
Synonyms: RG-6292; RO-7296682
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
