1815598-71-0
Chemical Structure
(5Z,2E)-CU-3
- CAS No.: 1815598-71-0
- Formula:C16H12N2O4S3
- Molecular Weight:392.47
IUPAC Name: N-((Z)-5-((E)-3-(furan-2-yl)allylidene)-4-oxo-2-thioxothiazolidin-3-yl)benzenesulfonamide
InChIKey: YIUMXULORVBWLL-SPGDJUBISA-N
SMILES: O=S(C1=CC=CC=C1)(NN(C/2=O)C(SC2=C/C=C/C3=CC=CO3)=S)=O
Biological Activity: (5Z,2E)-CU-3 is an isomer of CU-3 (HY-121638). CU-3 is a DGKα inhibitor with an IC50 of 0.6 μM. CU-3 competitively reduces DGKα’s affinity for ATP via binding to the enzyme’s catalytic region. CU-3 induces apoptosis in cancer cells. CU-3 promotes T-cell activation and enhances IL-2 production. CU-3 can be used for the research of hepatocellular carcinoma and cervical cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(5Z,2E)-CU-3 | 95.03% | (5Z,2E)-CU-3 is an isomer of CU-3 (HY-121638). CU-3 is a DGKα inhibitor with an IC50 of 0.6 μM. CU-3 competitively reduces DGKα’s affinity for ATP via binding to the enzyme’s catalytic region. CU-3 induces apoptosis in cancer cells. CU-3 promotes T-cell activation and enhances IL-2 production. CU-3 can be used for the research of hepatocellular carcinoma and cervical cancer. | ||||||||||||||||||||
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