2 Results for "

junctional epithelium

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "junctional epithelium" in MCE Product Catalog:

  • Targets Recommended:
Defensin HNP-3 human
Defensin HNP-3 human
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Cat. No.: HY-P2302
CAS No.: 136661-76-2
Target:  

Antibiotic Bacterial Fungal

Research Areas:  

Infection Inflammation/Immunology Cancer

Defensin HNP-3 human is an α-defensin stored in the azurophilic granules of human neutrophils. Defensin HNP-3 human exerts broad-spectrum bactericidal, antifungal and antiviral activities mainly by forming bacterial membrane pores, and acts as a chemoattractant for monocytes and T cells. Defensin HNP-3 human maintains epithelial integrity to support periodontal tissue homeostasis, and exerts concentration-dependent effects on epithelial cell proliferation, adhesion and bacterial adhesion. Defensin HNP-3 human targets solid tumors and leukemia by inducing single-strand DNA breaks and membrane permeabilization in tumor cells via electrostatic binding and pore formation. Defensin HNP-3 human is abundant in human tongue squamous cell carcinoma and neutrophils infiltrating oral squamous cell carcinoma. Defensin HNP-3 human can be applied to research related to periodontitis and human tongue squamous cell carcinoma .
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Pseudoginsenoside RT4
Pseudoginsenoside RT4
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Cat. No.: HY-N17685
CAS No.: 98474-77-2
Category:  

Panax vietnamensis Ha & Grushv. Plants Araliaceae Saccharides Monosaccharides

Target:  

Interleukin Related Bacterial TNF Receptor

Pseudoginsenoside RT4 is an orally active anti-inflammatory agent. Pseudoginsenoside RT4 can be isolated from Panax pseudoginseng subsp. Himalaicus, Panax vietnamensis Ha et Grushv, and Panax quinquefolius L. Pseudoginsenoside RT4 reduces the levels of TNF-α, IL-6, and IL-1β, elevates the level of IL-10, improves the histopathological features of colon tissue, maintains the ultrastructure of colonic epithelium, protects the integrity of cell monolayers, increases the expression of tight junction proteins, raises the total content of short-chain fatty acids, corrects intestinal flora disorder, reduces the disease activity index score, restores colon length, and decreases the spleen index. Pseudoginsenoside RT4 exhibits hepatoprotective effects. Pseudoginsenoside RT4 can be used in studies related to ulcerative colitis .
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