6 Results for "

leukemic HL-60 cells

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "leukemic HL-60 cells" in MCE Product Catalog:

Cat. No.: HY-W588250
CAS No.: 24730-31-2
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

Surfactin C1 is an amphiphilic biosurfactants. Surfactin C1 inhibits leukemic cell (HL-60) adhesion to human umbilical vein endothelial cells (HUVEC). Surfactin C1 inhibits adhesion melecules expression, such as ICAM-1 and VCAM-1 .
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Cat. No.: HY-118563
CAS No.: 135784-48-4
Farnesylthioacetic acid is a competitive, non-substrate inhibitor of Prenylcysteine α-carboxyl methyltransferase. It acts as a non-substrate competitive inhibitor of Arabidopsis thaliana Prenylcysteine α-carboxyl methyltransferase and blocks methyltransferase activity. Farnesylthioacetic acid does not inhibit protein farnesyltransferase activity in Arabidopsis. It induces Apoptosis. Farnesylthioacetic acid regulates the subcellular localization of Ras protein, reducing the proportion of cytoplasmic Ras protein without disrupting membrane binding. It enhances ABA-induced seed dormancy, delays seed germination, and promotes maximum stomatal closure at lower exogenous ABA concentrations. Farnesylthioacetic acid can be used in studies related to promyelocytic leukemia .
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Cat. No.: HY-117220
CAS No.: 1173040-34-0
Aspochalasin M is a colorless solid. Aspochalasin M shows modest activity against HL-60 cells with an IC50 of 20.0 μM. Aspochalasin M has the potential for the research of leukemic disease .
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Cat. No.: HY-119827
CAS No.: 107430-03-5
Synonyms: F 860191
Target:  

Topoisomerase

Research Areas:  

Cancer

Moflomycin (F 860191) is a compound with strong anti-leukemic activity and low mutagenicity. Moflomycin has an antiproliferative effect on the leukemic cell line HL60 in vitro (IC50=2.9 nM) . Moflomycin enhances topoisomerase II-induced DNA breaks and free radical production .
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Cat. No.: HY-158019
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Anticancer agent 196 (compound 1) shows cell cytotoxicity with IC50  values of  7.69 µM and  54.2 µM for HL-60 cells and A549 cells, respectively. Anticancer agent 196 can induce DNA damage .
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Cat. No.: HY-158020
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Anticancer agent 197 (compound 2b) shows cell cytotoxicity with IC50  values of  10.03 µM and  73.54 µM for HL-60 cells and A549 cells, respectively. Anticancer agent 197 can induce DNA damage .
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