Search Result

Results for "

luteinizing

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Androgen Receptor (1) Apoptosis (2) Biochemical Assay Reagents (2) CRFR (1) Cytochrome P450 (3) Dopamine Receptor (2) Drug Derivative (1) Drug Metabolite (1) Endogenous Metabolite (6) Environmental Pollutants (1) Estrogen Receptor/ERR (7) Ferroptosis (3) GABA Receptor (2) Glucocorticoid Receptor (3) GnRH Receptor (46) Histamine Receptor (4) Isotope-Labeled Compounds (7) Kisspeptin Receptor (2) mAChR (1) MDM-2/p53 (3) Neurokinin Receptor (3) Neuropeptide Y Receptor (1) PDI (3) PERK (1) Phosphatase (1) Prostaglandin Receptor (3) Ras (1) Reactive Oxygen Species (ROS) (3) Reference Standards (3) Sirtuin (3) TSH Receptor (2)
By Research Areas:	Cancer (17) Cardiovascular Disease (1) Endocrinology (59) Inflammation/Immunology (4) Metabolic Disease (11) Neurological Disease (18)

By Targets:

Adrenergic Receptor (1)

Androgen Receptor (1)

Apoptosis (2)

Biochemical Assay Reagents (2)

CRFR (1)

Cytochrome P450 (3)

Dopamine Receptor (2)

Drug Derivative (1)

Drug Metabolite (1)

Endogenous Metabolite (6)

Environmental Pollutants (1)

Estrogen Receptor/ERR (7)

Ferroptosis (3)

GABA Receptor (2)

Glucocorticoid Receptor (3)

GnRH Receptor (46)

Histamine Receptor (4)

Isotope-Labeled Compounds (7)

Kisspeptin Receptor (2)

mAChR (1)

MDM-2/p53 (3)

Neurokinin Receptor (3)

Neuropeptide Y Receptor (1)

PDI (3)

PERK (1)

Phosphatase (1)

Prostaglandin Receptor (3)

Ras (1)

Reactive Oxygen Species (ROS) (3)

Reference Standards (3)

Sirtuin (3)

TSH Receptor (2)

By Research Areas:

Cancer (17)

Cardiovascular Disease (1)

Endocrinology (59)

Inflammation/Immunology (4)

Metabolic Disease (11)

Neurological Disease (18)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-16168A

Degarelix Maximum Cited Publications 11 Publications Verification FE 200486 free base	GnRH Receptor Apoptosis	Endocrinology Cancer
Degarelix acetate (FE 200486) is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC₅₀ = 3 nM). Degarelix acetate Degarelix acetate (FE 200486) is used for the research of prostate cancer .

HY-P2293

Luteinizing hormone (human) 3 Publications Verification	Endogenous Metabolite	Endocrinology
Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction .

HY-130248

BAY-899 1 Publications Verification	GnRH Receptor	Endocrinology
BAY-899, a chemical probe, is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC₅₀s of 185 nM and 46nM for hLH (human LH) and rLH (rat LH), respectively. BAY-899 can reduce sex hormone levels .

HY-113157

Estrone 3-glucuronide	Drug Metabolite Endogenous Metabolite	Endocrinology
Estrone 3-glucuronide is a dominant urinary metabolite of Estradiol (HY-B0141) and urinary marker for female fertile window prediction. Estrone 3-glucuronide can be used in combination with luteinizing hormone in ovulation prediction kits ^[2].

HY-100209

Sufugolix TAK-013	GnRH Receptor	Endocrinology
Sufugolix (TAK-013) is a highly potent and orally available luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC₅₀ of 0.1 nM.

HY-P0243

Luteinizing Hormone Releasing Hormone (LH-RH), salmon Salmon GnRH; Salmon gonadotropin-releasing hormone; sGnRH	GnRH Receptor	Metabolic Disease
Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.

HY-100812

2-Hydroxysaclofen	GABA Receptor	Neurological Disease Endocrinology
2-Hydroxysaclofen is a potent γ-amino-butyric-acid-B (GABA_B) receptor antagonist. 2-Hydroxysaclofen can abolish nicotine-induced hypolocomotor effects and increases the antinociceptive effects. 2-Hydroxysaclofen can stimulate luteinizing hormone (LH) secretion in female rats .

HY-P3668

[D-Lys6]-LH-RH	GnRH Receptor	Endocrinology Cancer
[D-Lys6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH acts as a GnRH receptor agonist .

HY-P0009

Cetrorelix 1 Publications Verification SB-75	GnRH Receptor	Endocrinology
Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice .

HY-19464

Org 43553	GnRH Receptor Estrogen Receptor/ERR	Endocrinology
Org 43553 is an orally active and low molecular weight (LMW) luteinizing hormone receptor (LH-R) agonist. Org 43553 shows agonistic activity to human LH and FSH receptors with EC₅₀ values of 3.7 and 110 nM, respectively. Org 43553 can be used for the research of endocrine .

HY-130249

BAY-298	GnRH Receptor	Endocrinology
BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC₅₀s of 96 nM, 23 nM and 78 nM for hLH (human LH) and rLH (rat LH) and cLH (cynomolgus monkey LH), respectively. BAY-298 can reduce sex hormone levels .

HY-W041308

DCOIT Kathon 930	Environmental Pollutants GnRH Receptor	Endocrinology
DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor (GnRHR)-mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca ²⁺ signaling cascades .

HY-P1174

GnRH Associated Peptide (GAP) (1-13), human	GnRH Receptor	Endocrinology
GnRH Associated Peptide (GAP) (1-13), human is an amino acid peptide fragment derived from GnRH. GAP can increase the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in rat anterior pituitary cells. GAP also inhibit the secretion of prolactin .

HY-107939

Paramethasone Acetate	Glucocorticoid Receptor Cytochrome P450	Neurological Disease Metabolic Disease Inflammation/Immunology
Paramethasone Acetate is an orally active long-acting glucocorticoid. Paramethasone Acetate directly inhibits testicular aromatase, thereby reducing the synthesis of estradiol. Paramethasone Acetate suppresses the basal and midcycle luteinizing hormone surges in female animals and blocks estrogen synthesis. Paramethasone Acetate also decreases circulating levels of dihydrotestosterone, androstenedione and estradiol in male animals. Paramethasone Acetate inhibits cartilage degeneration and alleviates joint pathological damage in osteoarthritis models. Paramethasone Acetate can be used in research related to osteoarthritis and endocrinology .

HY-P4675

LHRH free acid	GnRH Receptor	Endocrinology Cancer
LHRH (free acid), the luteinizing hormone-releasing hormone, is a neuropeptide hypothalamic. LHRH regulates reproduction. LHRH can be used for the research of cancer .

HY-100271

Org41841	TSH Receptor	Endocrinology
Org41841 is a partial agonist of both luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and thyroid-stimulating hormone receptor (TSHR) with EC₅₀s of 0.2 and 7.7 μM, respectively.

HY-U00051

Propiomazine	Histamine Receptor Dopamine Receptor	Neurological Disease
Propiomazine is an orally active antihistamine agent. Propiomazine is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia .

HY-109532

Ganirelix acetate Ganirest	GnRH Receptor	Metabolic Disease
Ganirelix acetate (Ganirest) is a competitive and selective gonadotropin-releasing hormone (GnRH) antagonist. Ganirelix acetate blocks endogenous GnRH-induced release of luteinizing hormone (LH) and follicle-stimulating hormone. Ganirelix acetate antagonizes Prostaglandin E2 (HY-101952)-induced detrusor overactivity and enhances Carbachol (HY-B1208)-induced detrusor contraction. Ganirelix acetate is applicable to research related to female infertility and detrusor overactivity .

HY-113995

(-)-Vesamicol 1 Publications Verification (-)-AH5183	mAChR	Neurological Disease
(-)-Vesamicol (AH5183) is a vesicular acetylcholine transporter inhibitor. (-)-Vesamicol reversibly and non-competitively inhibits the transport of acetylcholine into circulating synaptic vesicles and blocks the activity of vesicular acetylcholine transporters in medial amygdala neurons. (-)-Vesamicol is applicable to research related to central precocious puberty .

HY-E70001

*Recombinant Human Luteinizing* Hormone**	Others	Endocrinology
Recombinant Human Luteinizing Hormone is a recombinant form of Luteinizing hormone (human) (HY-P2293). Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction .

HY-P4572

(D-Trp6)-LHRH free acid	GnRH Receptor	Cancer
(D-Trp6)-LHRH free acid is a luteinizing hormone-releasing hormone (LHRH) agonist .

HY-164764

ADX61623	Estrogen Receptor/ERR	Endocrinology
ADX61623 is a potent follicle stimulating hormone (FSH) receptor (FSHR) negative allosteric modulator (NAM). ADX61623 shows luteinizing hormone receptor (LH-R) activity and is not active on thyroid-stimulating hormone (TSH) receptors. ADX61623 can be used for the study of estrogen dependent disease .

HY-P11341

Kisspeptin antagonist p271	Kisspeptin Receptor	Endocrinology
Kisspeptin antagonist p271 is a Kisspeptin antagonist with cell-penetrating ability. Kisspeptin antagonist p271 can block the binding of endogenous Kisspeptin to GPR54 on pituitary somatotropes, thereby relieving the inhibition of growth hormone secretion. Kisspeptin antagonist p271 can specifically and significantly stimulate growth hormone secretion, while inhibiting luteinizing hormone without affecting prolactin or cortisol. Kisspeptin antagonist p271 can be used in the research of diseases related to insufficient growth hormone secretion .

HY-W009300

4-Hydroxyestrone 1 Publications Verification 4-OHE1	Endogenous Metabolite Estrogen Receptor/ERR Sirtuin MDM-2/p53 PDI Ferroptosis Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease Cancer
4-Hydroxyestrone (4-OHE1) is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on PDI to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

HY-P3605

GnRH Associated Peptide (25-53), human GAP (25-53), human	GnRH Receptor	Endocrinology
GnRH Associated Peptide (GAP) (25-53), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 25-53 fragment (hGAP-25-53), can be used as immunogen to generate antiseras including MC-1, MC-2, and MC-3. GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site .

HY-139303

LUF5771	GnRH Receptor	Endocrinology
LUF5771 is a potent allosteric recombinant luteinizing hormone (recLH) and Org 43553 inhibitor. LUF5771 is able to partially activate the LH receptor with low efficacy .

HY-P3668A

[D-Lys6]-LH-RH TFA	GnRH Receptor	Endocrinology Cancer
[D-Lys6]-LH-RH TFA is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH TFA acts as a GnRH receptor agonist .

HY-13699

NBI-42902	GnRH Receptor PERK	Others
NBI-42902 is an orally active, potent functional and competitive antagonist of GnRH receptor with an IC₅₀ value of 0.79 nM, a K_i value of 0.56 nM, respectively. NBI-42902 inhibits GnRH-stimulated inositol phosphate (IP) accumulation, Ca ²⁺ flux, and ERK1/2 activation. NBI-42902 inhibits serum luteinizing hormone (LH) in castrated male macaques. NBI-42902 can be used for research on sex-hormone-related diseases .

HY-P3975

Glp-His-Pro-Gly-NH2 pGlu-His-Pro-Gly-NH2	GnRH Receptor	Endocrinology
Glp-His-Pro-Gly-NH2 (pGlu-His-Pro-Gly-NH2) is a peptide containing 4 amino acids. Glp-His-Pro-Gly-NH2 stimulates gonadotrophin, luteinizing hormone (LH) and follicle stimulating hormone (FSH) release .

HY-P3666

[D-Phe2,6, Pro3]-LH-RH	GnRH Receptor	Endocrinology
[D-Phe2,6, Pro3]-LH-RH is a potent luteinizing hormone releasing hormone (LHRH) antagonist .

HY-131946

Menotropin Menotrophin	Biochemical Assay Reagents	Endocrinology
Menotropin (Menotrophin) is a hormone that can be extracted from the urine of postmenopausal women and has both follicle stimulating hormone (FSH) and luteinizing hormone (LH) activity .

HY-114707

Threonyl-seryl-lysine	GnRH Receptor	Endocrinology
Threonyl-seryl-lysine, a bovine pineal antireproductive tripeptide, has antigonadotropic activity. Threonyl-seryl-lysine binds to luteinizing hormone-releasing hormone (LHRH) at a site comprised of LHRH 2-5 .

HY-130660

Prostaglandin F2α ethanolamide Prostamide F2α	Prostaglandin Receptor	Endocrinology
Prostaglandin F2α ethanolamide (Prostamide F2α) is an ethanolamide-like G protein-coupled receptor. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord .

HY-130248B

(R)-BAY-899	GnRH Receptor	Others
(R)-BAY-899 is the R-enantiomer of BAY-899. BAY-899 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 185 nM and 46nM for hLH (human LH) and rLH (rat LH), respectively .

HY-P4144

Onvitrelin ucalontide Phor18-LHRH (338613); EP-100	GnRH Receptor	Endocrinology Cancer
Onvitrelin ucalontide ([Phor18-LHRH (338613)]) is an analogue of luteinizing hormone releasing hormone (LHRH) with antineoplastic activity. Onvitrelin ucalontide is a peptide with sequences of KFAKFAKKFAKFAKKFAKQHWSYGLRPG. Onvitrelin ucalontide effectively inhibits breast cancer, ovarian cancer and prostate cancer xenografts in mouse model .

HY-114810

Prostaglandin F2α serinol amide	Prostaglandin Receptor	Endocrinology
Prostaglandin F2α serinol amide is a serinolamide G protein-coupled receptor that increases calcium levels in human non-small cell lung cancer cells. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord .

HY-144863

BAY 1214784	GnRH Receptor	Cancer
BAY 1214784 is a potent, selective, and orally active antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R). BAY 1214784 is a spiroindoline derivative compound. BAY 1214784 effectively lowers plasma luteinizing hormone levels by up to 49%, at the same time being associated with low pharmacokinetic variability and good tolerability. BAY 1214784 has the potential for the research of uterine fibroids .

HY-P3084

Human follicular gonadotropin releasing peptide hF-GRP	GnRH Receptor	Endocrinology
Human follicular gonadotropin releasing peptide (hF-GRP) is a hormone peptide. Human follicular gonadotropin releasing peptide can stimulate pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion in vitro .

HY-W041308R

DCOIT (Standard) Kathon 930 (Standard)	GnRH Receptor Reference Standards	Endocrinology
DCOIT (Standard) is the analytical standard of DCOIT. This product is intended for research and analytical applications. DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor (GnRHR)-mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca2+ signaling cascades[1].

HY-P2115

Ramorelix	GnRH Receptor	Cancer
Ramorelix is a luteinizing-hormone-releasing hormone (LHRH) antagonist. Ramorelix can inhibit tumor progression in vivo. Ramorelix can be studied in anti-cancer research .

HY-129593

A-75998	GnRH Receptor	Endocrinology Cancer
A-75998 is an antagonist of luteinizing hormone-releasing hormone (LHRH). A-75998 can be used in the research of diseases such as hormone-sensitive cancers and endometriosis .

HY-16168B

Degarelix acetate hydrate FE 200486 acetate hydrate	GnRH Receptor Apoptosis	Endocrinology Cancer
Degarelix acetate hydrate (FE 200486 acetate hydrate) is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR/LHRHR) antagonist. Degarelix acetate hydrate can be used for prostate cancer research .

HY-B1155

Hydrocortisone phosphate Hydrocortisone 21-phosphate; Cortisol 21-phosphate	Phosphatase	Metabolic Disease Endocrinology
Hydrocortisone phosphate (Hydrocortisone 21-phosphate) is a derivative of the glucocorticoid Hydrocortisone hemisuccinate (HY-B1402) that increases serum luteinizing hormone (LH) levels. Hydrocortisone phosphate increases the activity of magnesium-dependent polymerases in the nucleolus. Hydrocortisone phosphate also serves as a substrate for alkaline phosphatase to localize phosphatases that hydrolyze steroid phosphates, and the role of alkaline phosphatase has been validated in adult mouse tissues .

HY-120767

Linzagolix choline KLH-2109 choline; OBE-2109 choline	GnRH Receptor	Inflammation/Immunology Cancer
Linzagolix choline (KLH-2109 choline) is a non-peptide gonadotropin-releasing hormone (GnRH) antagonist with oral activity. Linzagolix choline inhibits the release of endogenous gonadotropins such as luteinizing hormone LH and follicle-stimulating hormone FSH by binding to the GnRH receptor within the pituitary gland. This inhibition results in a reduction in the production of sex hormones such as estrogen and progesterone, which in turn affects the course of sex hormone-dependent diseases. Linzagolix choline can be used in the study of sex hormone-dependent diseases such as endometriosis and uterine fibroids .

HY-125701

A-76154	GnRH Receptor	Endocrinology
A-76154, an octapeptide, is a potent reduced-size luteinizing hormone-releasing hormone (LHRH) antagonist .

HY-P3604

LH-RH II (chicken)	Androgen Receptor	Endocrinology
LH-RH II (chicken) is one of the two forms of luteinizing hormone-releasing hormone (LHRH) the hypothalamus of the domestic hen, which are structural variants of mammalian LHRH. LH-RH II (chicken) enhances gonadotrophin release in the domestic chicken .

HY-107850A

5α-Pregnane-3α,20α-diol Allopregnanediol	GnRH Receptor	Endocrinology
5α-Pregnane-3α,20α-diol (Allopregnanediol) is a derivative of progesterone and is one of the various steroids secreted by the ovaries of rats. 5α-Pregnane-3α,20α-diol can significantly stimulate the release of luteinizing hormone (LH) in castrated rats that have been pre-treated with estrogen, while simultaneously inhibiting the secretion of follicle-stimulating hormone (FSH) .

HY-176546

NK3R-IN-2	Neurokinin Receptor	Endocrinology
NK3R-IN-2 is an orally active NK3R inhibitor with an IC₅₀ of 330.50 nM for human NK3R. NK3R-IN-2 can pass through the blood-brain barrier. NK3R-IN-2 has excellent NK3R binding affinity (IC₅₀ = 87.31 nM) in CHO-K1 cells. NK3R-IN-2 effectively inhibits the level of luteinizing hormone (LH). NK3R-IN-2 can be used for research on hormone related conditions .

HY-P3606

GnRH Associated Peptide (1-24), human GAP (1-24), human	GnRH Receptor	Endocrinology
GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fragment (hGAP-1-24). GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site .

HY-P2110

RS-18286	GnRH Receptor	Endocrinology
RS-18286 is a potent luteinizing-hormone (LH)-releasing hormone (LHRH) antagonist. RS-18286 blocks the pituitary LHRH receptor and suppresses pituitary luteinizing-hormone (LH) secretion and reduce serum concentrations of gonadal steroids .

Cat. No.	Product Name	Target	Research Area

HY-16168A

Degarelix Maximum Cited Publications 11 Publications Verification FE 200486 free base	GnRH Receptor Apoptosis	Endocrinology Cancer
Degarelix acetate (FE 200486) is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC₅₀ = 3 nM). Degarelix acetate Degarelix acetate (FE 200486) is used for the research of prostate cancer .

HY-P2293

Luteinizing hormone (human) 3 Publications Verification	Endogenous Metabolite	Endocrinology
Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction .

HY-P0243

Luteinizing Hormone Releasing Hormone (LH-RH), salmon Salmon GnRH; Salmon gonadotropin-releasing hormone; sGnRH	GnRH Receptor	Metabolic Disease
Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.

HY-P3668

[D-Lys6]-LH-RH	GnRH Receptor	Endocrinology Cancer
[D-Lys6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH acts as a GnRH receptor agonist .

HY-P0009

Cetrorelix 1 Publications Verification SB-75	GnRH Receptor	Endocrinology
Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice .

HY-P1174

GnRH Associated Peptide (GAP) (1-13), human	GnRH Receptor	Endocrinology
GnRH Associated Peptide (GAP) (1-13), human is an amino acid peptide fragment derived from GnRH. GAP can increase the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in rat anterior pituitary cells. GAP also inhibit the secretion of prolactin .

HY-P4675

LHRH free acid	GnRH Receptor	Endocrinology Cancer
LHRH (free acid), the luteinizing hormone-releasing hormone, is a neuropeptide hypothalamic. LHRH regulates reproduction. LHRH can be used for the research of cancer .

HY-P4572

(D-Trp6)-LHRH free acid	GnRH Receptor	Cancer
(D-Trp6)-LHRH free acid is a luteinizing hormone-releasing hormone (LHRH) agonist .

HY-P11341

Kisspeptin antagonist p271	Kisspeptin Receptor	Endocrinology
Kisspeptin antagonist p271 is a Kisspeptin antagonist with cell-penetrating ability. Kisspeptin antagonist p271 can block the binding of endogenous Kisspeptin to GPR54 on pituitary somatotropes, thereby relieving the inhibition of growth hormone secretion. Kisspeptin antagonist p271 can specifically and significantly stimulate growth hormone secretion, while inhibiting luteinizing hormone without affecting prolactin or cortisol. Kisspeptin antagonist p271 can be used in the research of diseases related to insufficient growth hormone secretion .

HY-P3605

GnRH Associated Peptide (25-53), human GAP (25-53), human	GnRH Receptor	Endocrinology
GnRH Associated Peptide (GAP) (25-53), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 25-53 fragment (hGAP-25-53), can be used as immunogen to generate antiseras including MC-1, MC-2, and MC-3. GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site .

HY-P3668A

[D-Lys6]-LH-RH TFA	GnRH Receptor	Endocrinology Cancer
[D-Lys6]-LH-RH TFA is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH TFA acts as a GnRH receptor agonist .

HY-P3975

Glp-His-Pro-Gly-NH2 pGlu-His-Pro-Gly-NH2	GnRH Receptor	Endocrinology
Glp-His-Pro-Gly-NH2 (pGlu-His-Pro-Gly-NH2) is a peptide containing 4 amino acids. Glp-His-Pro-Gly-NH2 stimulates gonadotrophin, luteinizing hormone (LH) and follicle stimulating hormone (FSH) release .

HY-P3666

[D-Phe2,6, Pro3]-LH-RH	GnRH Receptor	Endocrinology
[D-Phe2,6, Pro3]-LH-RH is a potent luteinizing hormone releasing hormone (LHRH) antagonist .

HY-114707

Threonyl-seryl-lysine	GnRH Receptor	Endocrinology
Threonyl-seryl-lysine, a bovine pineal antireproductive tripeptide, has antigonadotropic activity. Threonyl-seryl-lysine binds to luteinizing hormone-releasing hormone (LHRH) at a site comprised of LHRH 2-5 .

HY-P4144

Onvitrelin ucalontide Phor18-LHRH (338613); EP-100	GnRH Receptor	Endocrinology Cancer
Onvitrelin ucalontide ([Phor18-LHRH (338613)]) is an analogue of luteinizing hormone releasing hormone (LHRH) with antineoplastic activity. Onvitrelin ucalontide is a peptide with sequences of KFAKFAKKFAKFAKKFAKQHWSYGLRPG. Onvitrelin ucalontide effectively inhibits breast cancer, ovarian cancer and prostate cancer xenografts in mouse model .

HY-P3084

Human follicular gonadotropin releasing peptide hF-GRP	GnRH Receptor	Endocrinology
Human follicular gonadotropin releasing peptide (hF-GRP) is a hormone peptide. Human follicular gonadotropin releasing peptide can stimulate pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion in vitro .

HY-P2115

Ramorelix	GnRH Receptor	Cancer
Ramorelix is a luteinizing-hormone-releasing hormone (LHRH) antagonist. Ramorelix can inhibit tumor progression in vivo. Ramorelix can be studied in anti-cancer research .

HY-16168B

Degarelix acetate hydrate FE 200486 acetate hydrate	GnRH Receptor Apoptosis	Endocrinology Cancer
Degarelix acetate hydrate (FE 200486 acetate hydrate) is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR/LHRHR) antagonist. Degarelix acetate hydrate can be used for prostate cancer research .

HY-P3604

LH-RH II (chicken)	Androgen Receptor	Endocrinology
LH-RH II (chicken) is one of the two forms of luteinizing hormone-releasing hormone (LHRH) the hypothalamus of the domestic hen, which are structural variants of mammalian LHRH. LH-RH II (chicken) enhances gonadotrophin release in the domestic chicken .

HY-P3606

GnRH Associated Peptide (1-24), human GAP (1-24), human	GnRH Receptor	Endocrinology
GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fragment (hGAP-1-24). GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site .

HY-P2110

RS-18286	GnRH Receptor	Endocrinology
RS-18286 is a potent luteinizing-hormone (LH)-releasing hormone (LHRH) antagonist. RS-18286 blocks the pituitary LHRH receptor and suppresses pituitary luteinizing-hormone (LH) secretion and reduce serum concentrations of gonadal steroids .

HY-P4564

(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH	GnRH Receptor	Endocrinology
(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) .

HY-P4568

(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH	GnRH Receptor	Endocrinology
(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) .

HY-P4577

(D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH	GnRH Receptor	Endocrinology
(D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) .

HY-P2419

[Ala6]-LHRH	GnRH Receptor	Endocrinology
[Ala6]-LHRH is a synthetic luteinizing hormone-releasing hormone agonist, demonstrating effective stimulation of pituitary luteinizing hormone secretion. [Ala6]-LHRH enhances reproductive hormone regulation, contributing to fertility treatments. [Ala6]-LHRH plays a crucial role in managing conditions related to hormone imbalances.

HY-P2067

Argtide	GnRH Receptor	Endocrinology Cancer
Argtide is a luteinizing hormone-releasing hormone (LHRH) antagonist. Argtide is used in endometriosis and cancer-related research .

HY-106043

Lutrelin Wy 40972	GnRH Receptor	Endocrinology
Lutrelin (Wy 40972) is a luteinizing hormone releasing hormone (LHRH) agonist. Lutrelin inhibits the growth of the endometrial expiant in rats .

HY-P3672

[D-Ala6]-LH-RH	GnRH Receptor	Endocrinology
[D-Ala6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Ala6]-LH-RH acts as a GnRH receptor agonist .

HY-P10594

Myr-Arf1(2–17)	Ras	Endocrinology
Myr-Arf1(2–17) is a sarcosinated peptide that mimics the localization and function of Arf1 protein on the cell membrane. Myr-Arf1(2–17) can be used to study the desensitization mechanism of luteinizing hormone/chorionic gonadotropin receptor (LH/CGR) .

HY-P3671

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH	GnRH Receptor	Endocrinology
[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH acts as a GnRH receptor antagonist .

HY-P0262A

Galantide TFA	Neuropeptide Y Receptor	Neurological Disease Metabolic Disease
Galantide TFA is a reversible and non-specific galanin (GAL) receptor antagonist. Galantide TFA dose-dependently shows antagonism to galanin-induced K ⁺ conductance with an IC₅₀ value of 4 nM. Galantide TFA can be used for the research of neurological disease and hormone metabolism research .

HY-P4542

(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)	CRFR	Endocrinology
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a CRF antagonist. (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) prevents the IL-1a induced Luteinizing hormone (LH) inhibition .

HY-P10490

(D-His(Bzl)6)-LHRH (1-7) free acid	Drug Derivative GnRH Receptor	Others Cancer
(D-His(Bzl)6)-LHRH (1-7) free acid is a synthetic peptide compound that is a derivative of luteinizing hormone-releasing hormone (LHRH). (D-His(Bzl)6)-LHRH (1-7) free acid enhances its stability and biological activity by introducing unnatural amino acid residues at specific positions of the LHRH molecule. This modification can improve the drug's performance in the body half-life, reducing the rate at which it is rapidly metabolized and cleared, thereby enhancing its efficacy in inhibiting cell proliferation .

HY-P3048

[Gln4]-Neurotensin	Endogenous Metabolite	Neurological Disease
[Gln4]-Neurotensin is an amide analog that releases luteinizing hormone and follicle-stimulating hormone .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992149

Lutropin alfa	GnRH Receptor	Endocrinology
Lutropin alfa is a recombinant human luteinizing hormone (LH). Lutropin alfa consists of non-covalently linked α and β subunits, and its activity is similar to that of natural luteinizing hormone. Lutropin alfa is used to stimulate follicular development in infertility .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113157

Estrone 3-glucuronide	Structural Classification Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Steroids Source Classification	Drug Metabolite Endogenous Metabolite
Estrone 3-glucuronide is a dominant urinary metabolite of Estradiol (HY-B0141) and urinary marker for female fertile window prediction. Estrone 3-glucuronide can be used in combination with luteinizing hormone in ovulation prediction kits ^[2].

HY-W009300

4-Hydroxyestrone 1 Publications Verification 4-OHE1	Structural Classification Animals Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite Estrogen Receptor/ERR Sirtuin MDM-2/p53 PDI Ferroptosis Reactive Oxygen Species (ROS)
4-Hydroxyestrone (4-OHE1) is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on PDI to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

Species:	Human (3) Mouse (1) Rat (2)
Tag:	His (5) Tag Free (1)
Source:	HEK293 (4) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P705680

	Lhcgr Protein, Rat (His) Lhcgr; Lutropin-choriogonadotropic hormone receptor; LH/CG-R; luteinizing hormone receptor; LSH-R	Rat	E. coli

HY-P705705

	Lhb Protein, Rat (His) Lutropin subunit beta; Lutropin beta chain; luteinizing hormone subunit beta (LH-B; LSH-B; LSH-beta); Lhb	Rat	E. coli

HY-P7869

	CG alpha Protein, Human (HEK293, His) rHuGlycoprotein hormones alpha chain/CGA, His; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; luteinizing hormone alpha chain; LSH-alph	Human	HEK293
	The CG alpha protein, a shared alpha chain in glycoprotein hormones (TSH, LH, FSH, CG), binds to receptors, initiating signaling pathways. Heterodimeric hormones involve CG alpha and a specific beta chain (TSHB, LHB, FSHB, CGB), imparting biological specificity. CG alpha Protein, Human (HEK293, His) is the recombinant human-derived CG alpha protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70205

	Progonadoliberin-2/GNRH II Protein, Human (HEK293, His) rHuProgonadoliberin-2/GnRH II, His; Progonadoliberin-2; Progonadoliberin II; Gonadoliberin-2; Gonadoliberin II; Gonadotropin-Releasing Hormone II; GnRH II; Luliberin II; luteinizing Hormone-Releasing Hormone II; LH-RH II; GnRH-Associated Peptide 2; GnRH-Associated Peptide II; GNRH2	Human	HEK293
	Progonadoliberin-2/GNRH II Proteinas, a pivotal player in the endocrine system, potently stimulates gonadotropin secretion, promoting both luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release. Its capacity to orchestrate the secretion of these hormones underscores its significance in governing reproductive functions within the intricate endocrine signaling network that regulates the reproductive axis. Progonadoliberin-2/GNRH II Protein, Human (HEK293, His) is the recombinant human-derived Progonadoliberin-2/GNRH II protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P7870

	CGA-CGB3 Heterodimer Protein, Human (HEK293, His) rHuGlycoprotein hormones alpha chain, C-Flag&Choriogonadotropin subunit beta 3, His; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; luteinizing hormone alpha chain; LSH-alph	Human	HEK293
	The CG alpha protein, a shared alpha chain in glycoprotein hormones (TSH, LH, FSH, CG), binds to receptors, initiating signaling pathways. Heterodimeric hormones involve CG alpha and a specific beta chain (TSHB, LHB, FSHB, CGB), imparting biological specificity. CGA-CGB3 Heterodimer Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived CGA-CGB3 Heterodimer protein, expressed by HEK293 , with C-6*His labeled tag. CGA-CGB3 Heterodimer Protein, Human (HEK293, His), has molecular weight of 22 & 30-35 kDa, respectively.

HY-P703477

	TSH Protein, Mouse (HEK293) Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain; Cga; Mus musculus; Mouse; FSH-alpha; Hormone	Mouse	HEK293
	TSH Protein, Mouse (HEK293) is the recombinant mouse-derived TSH, expressed by HEK293 , with tag Free labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-B1617AS

Zuclomiphene-d4 citrate
Zuclomiphene-d₄ citrate is a deuterium labeled Zuclomiphene citrate (HY-B1617A). Zuclomiphene citrate is a cis isomer of Clomiphene citrate (HY-B0463). Zuclomiphene citrate is orally active and has an antiestrogenic effect. Zuclomiphene can reduce cholesterol levels. Zuclomiphene citrate can be for the researches of endocrinology and metabolic disease .

HY-P0009S1

Cetrorelix-d10
Cetrorelix-d₁₀ (SB-75-d₁₀) is deuterium labeled Cetrorelix. Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice .

HY-U00051AS1

(R)-Propiomazine-d6 hydrochloride

(R)-Propiomazine-d₆ hydrochloride is deuterium labeled Propiomazine hydrochloride. Propiomazine hydrochloride is an orally active antihistamine agent. Propiomazine hydrochloride is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine hydrochloride is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia.

HY-U00051AS

Propiomazine-d6 hydrochloride

Propiomazine-d₆ hydrochloride is deuterium labeled Propiomazine hydrochloride. Propiomazine hydrochloride is an orally active antihistamine agent. Propiomazine hydrochloride is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine hydrochloride is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia.

HY-U00051AS2

(S)-Propiomazine-d6 hydrochloride

(S)-Propiomazine-d₆ hydrochloride is deuterium labeled Propiomazine hydrochloride. Propiomazine hydrochloride is an orally active antihistamine agent. Propiomazine hydrochloride is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine hydrochloride is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia.

HY-W009300S

4-Hydroxyestrone-d4

4-Hydroxyestrone (4-OHE1)-d₄ is the deuterium labeled 4-Hydroxyestrone (HY-W009300). 4-Hydroxyestrone is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on PDI to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

HY-W009300S1

4-Hydroxyestrone-13C6

4-Hydroxyestrone (4-OHE1)- ¹³C₆ is a ¹³C-labeled 4-Hydroxyestrone (HY-W009300). 4-Hydroxyestrone is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on PDI to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

Host:	Mouse (2) Rabbit (4)
Reactivity:	Human (6) Mouse (2)
Application:	IHC-P (4) IF-Tissue (2) IHC-F (2) WB (2) ELISA (2)
Isotype:	IgG (6)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (3) Recombinant (2)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81350

	Luteinizing Hormone beta Antibody (YA1095) CGB4; hLHB; LSH-B	IHC-P	Human
	Luteinizing Hormone beta Antibody (YA1095) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Luteinizing Hormone beta.

HY-P81350A

	Luteinizing Hormone beta Antibody (YA1095)(PBS only) CGB4; hLHB; LSH-B	IHC-P	Human
	Luteinizing Hormone beta Antibody (YA1095) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Luteinizing Hormone beta.

HY-P81192

	StAR Antibody (YA3542) StARD1; Cholesterol trafficker; luteinizing hormone induced protein; Mitochondrial steroid acute regulatory protein; StAR related lipid transfer (START) domain containing 1; StARD1; START domain containing protein 1; Steroidogenic Acute Regulatory Protein; Steroidogenic acute regulatory protein mitochondrial; STAR_HUMAN.	WB	Human, Mouse
	StAR Antibody (YA3542) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to StAR.

HY-P81192A

	StAR Antibody (YA3542)(PBS only) StARD1; Cholesterol trafficker; luteinizing hormone induced protein; Mitochondrial steroid acute regulatory protein; StAR related lipid transfer (START) domain containing 1; StARD1; START domain containing protein 1; Steroidogenic Acute Regulatory Protein; Steroidogenic acute regulatory protein mitochondrial; STAR_HUMAN.	WB	Human, Mouse
	StAR Antibody (YA3542) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to StAR.

HY-P86714

	CGA/hCG alpha Antibody (YA6406) GLHA_HUMAN; Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha(CG-alpha); Follicle-stimulating hormone alpha chain(FSH-alpha); Follitropin alpha chain; luteinizing hormone alpha chain(LSH-alpha); Lutropin alpha chain; Thyroid-stimulating hormone alpha chain(TSH-alpha); Thyrotropin alpha chain; glycoprotein hormones, alpha polypeptide; HCG alpha;	IHC-P, IHC-F, IF-Tissue, ELISA	Human
	CGA/hCG alpha Antibody (YA6406) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CGA/hCG alpha.

HY-P86714A

	CGA/hCG alpha Antibody (YA6406)(PBS only) GLHA_HUMAN; Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha(CG-alpha); Follicle-stimulating hormone alpha chain(FSH-alpha); Follitropin alpha chain; luteinizing hormone alpha chain(LSH-alpha); Lutropin alpha chain; Thyroid-stimulating hormone alpha chain(TSH-alpha); Thyrotropin alpha chain; glycoprotein hormones, alpha polypeptide; HCG alpha;	IHC-P, IHC-F, IF-Tissue, ELISA	Human
	CGA/hCG alpha Antibody (YA6406) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CGA/hCG alpha.