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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
mitochondria isoform
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "mitochondria isoform" in MCE Product Catalog:
TM-1 is a potent inhibitor of pyruvate dehydrogenase kinase (PDHK1). TM-1 inhibits PDHK1 and PDHK2 with IC50s of 2.97 μM and 5.2 μM, respectively. TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation, and inhibits cell proliferation .
Cat. No.: HY-137782
CAS No.: 18198-76-0
Target:
Cat. No.: HY-137782B
CAS No.: 324518-22-1
Target:
Research Areas:
Palmitoleoyl-CoA lithium is the lithium salt form of Palmitoleoyl-CoA (HY-137782). Palmitoleoyl-CoA lithium can be activated and transported into the mitochondria for metabolism, specifically for β-oxidation. Palmitoleoyl-CoA lithium induces the cardiac mitochondrial membrane permeability transition, which causes mitochondrial dysfunction. Palmitoleoyl-CoA lithium regulates metabolism via allosteric control of AMPK β1-isoforms .
Cat. No.: HY-137782A
CAS No.: 1246304-41-5
Target:
Research Areas:
Palmitoleoyl-CoA triammonium is the triammonium salt form of Palmitoleoyl-CoA (HY-137782). Palmitoleoyl-CoA triammonium can be activated and transported into the mitochondria for metabolism, specifically for β-oxidation. Palmitoleoyl-CoA triammonium induces the cardiac mitochondrial membrane permeability transition, which causes mitochondrial dysfunction. Palmitoleoyl-CoA triammonium regulates metabolism via allosteric control of AMPK β1-isoforms .
Cat. No.: HY-P2809B
Target:
Research Areas:
Malic Dehydrogenase, Porcine (EC 1.1.1.37) exists as two isoforms within eukaryotic cells, one that is expressed in the mitochondria and functions in the TCA cycle and one in the cytoplasm that converts malate from the mitochondria back into oxaloacetate.
Cat. No.: HY-P2809D
Target:
Research Areas:
Malic Dehydrogenase, Bovine (EC 1.1.1.37) exists as two isoforms within eukaryotic cells, one that is expressed in the mitochondria and functions in the TCA cycle and one in the cytoplasm that converts malate from the mitochondria back into oxaloacetate.
Cat. No.: HY-P2809C
Target:
Research Areas:
Malic Dehydrogenase (oxaloacetate-decarboxylating), Chicken (EC 1.1.1.40) exists as two isoforms within eukaryotic cells, one that is expressed in the mitochondria and functions in the TCA cycle and one in the cytoplasm that converts malate from the mitochondria back into oxaloacetate.
Cat. No.: HY-184945
CAS No.: 252016-13-0
Research Areas:
PDK ligand-1 (Compound 16) is a target protein ligand that serves as an HsClpP recruitment module for constructing mitochondrially targeted pan-PDK degraders. PDK ligand-1 can be used for the synthesis of Pan-PDK degrader-1 (HY-184943) .
Cat. No.: HY-E70854
Target:
Research Areas:
PKCε is an isoform of the large PKC family of protein kinases. In cardiac muscle cells, PKCε regulates muscle contraction through its actions at sarcomeric proteins, and PKCε modulates cardiac cell metabolism through its actions at mitochondria. PKCε Recombinant Human Active Protein Kinase is a recombinant PKCε protein that can be used to study PKCε-related functions .
Cat. No.: HY-P71367
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PAM16; Presequence Translocated-Associated Motor Subunit PAM16; Presequence Translocase Associated Motor 16; HCG15164, isoform CRA_a; TIMM16; Magmas-Like Protein; mitochondria-Associated Granulocyte Macrophage CSF-Signaling Molecule; CORO7-PAM16; Magmas;
Species:
Others
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
