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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10000 Results for "
modified nucleotides
" in MedChemExpress (MCE) Product Catalog:
Products (10000)
10000 Results for "modified nucleotides" in MCE Product Catalog:
13
13 Publications Verification
Cat. No.: HY-RI04602
MicroRNA Inhibitor Negative Control is a full-length nucleotide 2'-methoxy modified oligonucleotide, and can be used as a negative control. The sequence of MicroRNA Inhibitor Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.
3
3 Cited Publications
Synonyms: N1-Methylinosine
3
3 Cited Publications
Cat. No.: HY-RI04602A
MicroRNA Antagomir Negative Control is a chemically-modified oligonucleotide (2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification), and can be used as a negative control. The sequence of MicroRNA Antagomir Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.
3
3 Cited Publications
Cat. No.: HY-RI00449A
hsa-miR-21-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
1
1 Cited Publications
Cat. No.: HY-112582A
CAS No.: 1428903-59-6
Synonyms: 1-Methylpseudouridine-5′-triphosphate
1
Research Areas:
5-Iodo-cytidine (5-Iodo-D-cytidine) is a purine nucleoside analog that acts as an intermediate in organic synthesis. 5-Iodo-cytidine serves as a chemically modified nucleotide to replace partial cytidine residues in in vitro transcription, enhancing the translation efficiency and stability of chemically modified mRNA. Purine nucleoside analogs exhibit broad anti-tumor activity and target indolent lymphoid malignancies. 5-Iodo-cytidine can be used in mRNA therapy and tumor-related research .
1
1 Cited Publications
Synonyms: 1-Methylpseudouridine-5′-triphosphate trisodium; N1-Me-Pseudo UTP trisodium; N1-Methyl-Pseudo-UTP trisodium
1
1 Cited Publications
Synonyms: N3-Methyluridine
Target:
1
1 Cited Publications
Cat. No.: HY-W009444
CAS No.: 1463-10-1
Target:
Cat. No.: HY-W570884
CAS No.: 1873306-74-1
Target:
Research Areas:
5-Me-dC(Ac) amidite is an acetyl (Ac)-modified nucleotide commonly used in the synthesis of modified oligonucleotides.
Cat. No.: HY-156905
CAS No.: 1202854-87-2
Target:
Research Areas:
6-Azido-N-acetylgalactosamine-UDP (Compound 5) is a 6-azido-modified nucleotide sugar. It acts as an active sugar donor in lactose glycosylation catalyzed by beta-1,3-N-Acetylhexaminyltransferase (LgtA). Azido-modified nucleotide sugars are strategically used in copper-free click chemistry to modify the N-glycan core structure of IgG .
Synonyms: 5-Propargylamino-dUTP
Cat. No.: HY-112581B
Purity: 99.89%
Synonyms: 5-Methoxy-UTP trisodium solution (100 mM); 5-OMe-UTP trisodium solution (100 mM)
5'-O-DMT-N4-Ac-2'-F-dC is a modified nucleotide commonly used in the synthesis of modified oligonucleotides.
Cat. No.: HY-132598A
Purity: 99.44%
Synonyms: SPC-3649 sodium
Miravirsen sodium is a potent miR-122 inhibitor and inhibits the biogenesis of miR-122. Miravirsen sodium is a 15-nucleotide locked nucleic acid-modified phosphorothioate antisense oligonucleotide. Miravirsen sodium inhibits HCV replication, and can be used in research of HCV infection .
Cat. No.: HY-132598
CAS No.: 1072874-90-8
Synonyms: SPC-3649
Research Areas:
Miravirsen (SPC-3649) is a potent miR-122 inhibitor and inhibits the biogenesis of miR-122. Miravirsen is a 15-nucleotide locked nucleic acid-modified phosphorothioate antisense oligonucleotide. Miravirsen inhibits HCV replication. Miravirsen can be used in research of HCV infection .
Cat. No.: HY-132146A
Purity: ≥99.0%
Cat. No.: HY-W590551
CAS No.: 29220-54-0
Target:
Research Areas:
Adenosine 5′-O-(1-thiotriphosphate) is an α-Phosphate modified adenosine nucleotide.
Cat. No.: HY-W881465
CAS No.: 2172373-55-4
Target:
Research Areas:
5'(E)-VP-2'-OMe-U Phosphoramidite is a phosphoramidite nucleotide precursor compound, mainly used to synthesize stable and functionalized modified oligonucleotides for the research and synthesis of nucleic acid drugs.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
