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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
67 Results for "
nitrogen-containing
" in MedChemExpress (MCE) Product Catalog:
Products (67)
67 Results for "nitrogen-containing" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-B0012
CAS No.: 40391-99-9
Research Areas:
Pamidronic acid, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronic acid significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of OPG in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronic acid can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma .
1
Research Areas:
Pamidronate disodium (CGP 23339A), the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma .
1
1 Cited Publications
Cat. No.: HY-B0730
CAS No.: 109552-15-0
Research Areas:
Pamidronate disodium pentahydrate, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium pentahydrate significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium pentahydrate can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma .
Synonyms: N-Acetyl-D-lactosamine
Category:
Target:
Cat. No.: HY-W013040
CAS No.: 290-37-9
Synonyms: 1,4-Diazine
Target:
Research Areas:
Cardiovascular Disease Infection Inflammation/Immunology Cancer
Pyrazine (1,4-Diazine) is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities .
Cat. No.: HY-W034566
CAS No.: 296-35-5
Synonyms: Hexaaza-18-crown-6; 1,4,7,10,13,16-Hexaazacyclooctadecane
Target:
Cat. No.: HY-W002457
CAS No.: 26621-44-3
Cat. No.: HY-159051
CAS No.: 39775-75-2
Cat. No.: HY-W010628
CAS No.: 36520-39-5
Synonyms: Trimethyleneimine hydrochloride
Cat. No.: HY-P4545
CAS No.: 67482-93-3
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Cat. No.: HY-W002718
CAS No.: 16063-69-7
Research Areas:
2,4,6-Trichloropyridine is a trichloro-substituted nitrogen-containing heterocyclic compound that serves as an intermediate for studies related to organic synthesis. 2,4,6-Trichloropyridine reacts with n-BuLi to form a stable 3-lithiated pyridine intermediate .
Cat. No.: HY-W002458
CAS No.: 2075-46-9
Cat. No.: HY-P4561
CAS No.: 90331-82-1
Cat. No.: HY-P4725
CAS No.: 133233-38-2
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Research Areas:
Cat. No.: HY-B0515A
CAS No.: 114084-78-5
Ibandronic acid is a highly effective nitrogen-containing bisphosphonate that can be used for osteoporosis.
Cat. No.: HY-W024652
CAS No.: 2302-39-8
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Research Areas:
4,5-Dimethylimidazole is a nitrogen-containing heterocyclic compound and is a synthetic intermediate .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
