2075-46-9
2075-46-9
Chemical Structure
4-Nitropyrazole
- CAS No.: 2075-46-9
- Formula:C3H3N3O2
- Molecular Weight:113.08
IUPAC Name: 4-nitro-1H-pyrazole
InChIKey: XORHNJQEWQGXCN-UHFFFAOYSA-N
SMILES: O=[N+](C1=CNN=C1)[O-]
Biological Activity: 4-Nitropyrazole is a five-membered nitrogen-containing heterocyclic compound that can be used as a drug intermediate. 4-Nitropyrazole can be synthesized into antibiotics/antifungal/antiviral agents containing pyrazole rings. 4-Nitropyrazole is synthesized through C-H activation reactions to produce LRRK2 inhibitors, which are used in the research of Parkinson's disease[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
4-Nitropyrazole | 99.99% | 4-Nitropyrazole is a five-membered nitrogen-containing heterocyclic compound that can be used as a drug intermediate. 4-Nitropyrazole can be synthesized into antibiotics/antifungal/antiviral agents containing pyrazole rings. 4-Nitropyrazole is synthesized through C-H activation reactions to produce LRRK2 inhibitors, which are used in the research of Parkinson's disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Manfredini S,et al. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-one nucleosides. J Med Chem. 1992 Mar 6;35(5):917-24. [Content Brief]
- [2]. Barron B, et al. A Concise Enantioselective Synthesis of Fluorinated Pyrazolo-Piperidine GSK3901383A Enabled by an Organocatalytic Aza-Michael Addition. Org Lett. 2024 Mar 1;26(8):1533-1538. [Content Brief]
- [3]. Hrelia P, et al. Synthesis, metabolism and structure-mutagenicity relationships of novel 4-nitro-(imidazoles and pyrazoles) in Salmonella typhimurium. Mutat Res. 1998 Feb 2;397(2):293-301. [Content Brief]
Keywords
