85 Results for "

ornithine

" in MedChemExpress (MCE) Product Catalog:
Products (85)

85 Results for "ornithine" in MCE Product Catalog:

22
Eflornithine
Eflornithine
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22 Publications Verification
Cat. No.: HY-B0744
CAS No.: 70052-12-9
Synonyms: DFMO; MDL71782; RMI71782; α-difluoromethylornithine
Target:  

Parasite

Domaines de recherche:  

Infection Cancer

Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
22
Eflornithine hydrochloride hydrate
Eflornithine hydrochloride hydrate
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22 Publications Verification
Cat. No.: HY-B0744B
CAS No.: 96020-91-6
Synonyms: DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate
Target:  

Parasite

Domaines de recherche:  

Cancer

Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .
22
Eflornithine hydrochloride
Eflornithine hydrochloride
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22 Publications Verification
Cat. No.: HY-B0744A
CAS No.: 68278-23-9
Synonyms: DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride
Target:  

Parasite

Domaines de recherche:  

Infection Cancer

Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
11
AMXT-1501 tetrahydrochloride
AMXT-1501 tetrahydrochloride
0 Images
11 Cited Publications
Cat. No.: HY-124617A
CAS No.: 2444815-84-1
Pureté:  ≥98.0%
Target:  

Apoptosis Bacterial

Domaines de recherche:  

Infection Inflammation/Immunology Cancer

AMXT-1501 tetrahydrochloride is a Bacterial agent and polyamine transport system inhibitor. AMXT-1501 tetrahydrochloride targets membrane phospholipids and exhibits antibacterial activity against a variety of Gram-positive and Gram-negative multidrug-resistant bacteria . AMXT-1501 tetrahydrochloride inhibits capsular biosynthesis in Streptococcus pneumoniae . AMXT-1501 tetrahydrochloride targets ornithine decarboxylase and polyamines to inhibit the proliferation of neuroblastoma cells . AMXT-1501 tetrahydrochloride in combination with DFMO (HY-B0744) induces Apoptosis in neuroblastoma cells. AMXT-1501 tetrahydrochloride is applicable to research related to multidrug-resistant bacterial infections, pneumococcal infections, Streptococcus pneumoniae infections, and neuroblastoma .
11
AMXT-1501
AMXT-1501
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11 Cited Publications
Cat. No.: HY-124617
CAS No.: 441022-64-6
Pureté:  99.44%
Target:  

Apoptosis Bacterial

Domaines de recherche:  

Infection Cancer

AMXT-1501 is a Bacterial agent and polyamine transport system inhibitor. AMXT-1501 targets membrane phospholipids and exhibits antibacterial activity against a variety of Gram-positive and Gram-negative multidrug-resistant bacteria . AMXT-1501 inhibits capsular biosynthesis in Streptococcus pneumoniae . AMXT-1501 targets ornithine decarboxylase and polyamines to inhibit the proliferation of neuroblastoma cells . AMXT-1501 in combination with DFMO (HY-B0744) induces Apoptosis in neuroblastoma cells. AMXT-1501 is applicable to research related to multidrug-resistant bacterial infections, pneumococcal infections, Streptococcus pneumoniae infections, and neuroblastoma .
9
L-Ornithine
L-Ornithine
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9 Cited Publications
Cat. No.: HY-B1352
CAS No.: 70-26-8
Synonyms: (S)-2,5-Diaminopentanoic acid
Category:  

Anti-aging Ketones, Aldehydes, Acids Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder

Target:  

Arginase Endogenous Metabolite

L-Ornithine ((S)-2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective .
9
L-Ornithine hydrochloride
L-Ornithine hydrochloride
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9 Cited Publications
Cat. No.: HY-W017018
CAS No.: 3184-13-2
Category:  

Microorganisms Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .
6
L-Citrulline
L-Citrulline
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6 Cited Publications
Cat. No.: HY-N0391
CAS No.: 372-75-8
Category:  

Other Diseases Disease markers Endocrine diseases Amino acids Nervous System Disorder Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.
5
Herbacetin
Herbacetin
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5 Cited Publications
Cat. No.: HY-N0240
CAS No.: 527-95-7
Category:  

Flavonols Linum usitatissimum Linn. Flavonoids Linaceae Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

Ornithine decarboxylase (ODC)

Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .
4
Sinefungin
Sinefungin
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4 Cited Publications
Cat. No.: HY-101938
CAS No.: 58944-73-3
Pureté:  99.91%
Synonyms: Adenosyl-ornithine; A-9145; Antibiotic 32232RP
Target:  

Histone Methyltransferase Fungal Antibiotic Parasite

Domaines de recherche:  

Infection Inflammation/Immunology

Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication . Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation .
1
N-Acetylornithine
N-Acetylornithine
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1 Cited Publications
Cat. No.: HY-113080
CAS No.: 6205-08-9
Pureté:  ≥98.0%
Category:  

Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Others

N-Acetylornithine is a precursor of ornithine. N-Acetylornithine is associated with type 2 diabetes .
1
ODC1 Protein, Human (His-T7)
ODC1 Protein, Human (His-T7)
0 Images
1 Cited Publications
Cat. No.: HY-P71109
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ornithine decarboxylase; ODC1;
Species:  
Human
Source:  
E. coli
Poly-L-ornithine hydrobromide (MW 30000-70000)
Poly-L-ornithine hydrobromide (MW 30000-70000)
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Cat. No.: HY-126436A
CAS No.: 27378-49-0
Synonyms: L-ornithine homopolymer hydrobromide (MW 30000-70000)
Poly-L-ornithine hydrobromide (MW 30000-70000) is a poly-lysine derivative with a molecular weight of 30000-70000. Poly-L-ornithine hydrobromide (MW 30000-70000) binds to the surface of cell culture vessels through positively charged amino acid residues to form a coating that promotes cell adhesion and provides cells with a matrix environment required for growth. Poly-L-ornithine hydrobromide (MW 30000-70000) is used as a coating agent in cell culture and can be used for the study of primary culture of neurons (such as dopaminergic neurons and oligodendrocytes) .
L-Citrulline-d7
L-Citrulline-d7
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Cat. No.: HY-N0391S5
CAS No.: 2483831-24-7
L-Citrulline-d7 is the deuterium labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.
L-Ornithine L-aspartate
L-Ornithine L-aspartate
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Cat. No.: HY-A0282
CAS No.: 3230-94-2
Target:  

Amino Acid Derivatives

Domaines de recherche:  

Metabolic Disease Inflammation/Immunology

L-Ornithine L-aspartate is a stable salt of two natural nonessential L-amino acids with oral activity: ornithine and aspartic acid. L-Ornithine L-aspartate lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis. L-Ornithine L-aspartate also improves mitochondrial functions .
3-Amino-2-piperidinone
3-Amino-2-piperidinone
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Cat. No.: HY-21088
CAS No.: 1892-22-4
Synonyms: Cyclo-ornithine
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Drug Intermediate

3-Amino-2-piperidinone (Cyclo-ornithine) is a cyclic ornithine analogue and can be used as drug intermediate .
L-Canaline
L-Canaline
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Cat. No.: HY-129476
CAS No.: 496-93-5
Pureté:  ≥95.0%
Category:  

Infection other families Amino acids Plants Endogenous metabolite Disease Research Fields

Target:  

Parasite Endogenous Metabolite

L-Canaline is a nonprotein amino acid stored in many leguminous plants. L-Canaline is a cytotoxic metabolite catalyzed by L-canavanine and its arginase. L-Canaline is a potent and irreversible inhibitor of ornithine aminotransferase. L-Canaline inhibits the growth of the malaria parasite Plasmodium falciparum with an IC50 of 297 nM. L-Canaline has anticancer and antiproliferative effects .
D-Ornithine hydrochloride
D-Ornithine hydrochloride
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Cat. No.: HY-34516
CAS No.: 16682-12-5
Synonyms: (R)-ornithine hydrochloride
Category:  

Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Bacterial

D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins .
L-Ornithine-1,2,3,4,5-13C5 hydrochloride
L-Ornithine-1,2,3,4,5-13C5 hydrochloride
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Cat. No.: HY-W017018S2
CAS No.: 943962-21-8
L-Ornithine-1,2,3,4,5- 13C5 (hydrochloride) is the 13C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.
Ivospemin
Ivospemin
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Cat. No.: HY-132822
CAS No.: 748119-79-1
Pureté:  99.71%
Synonyms: SBP-101
Target:  

Drug Derivative

Domaines de recherche:  

Cancer

Ivospemin (SBP-101) is an antineoplastic spermine analog. Ivospemin has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo. Ivospemin shows modest induction of polyamine catabolism, but stronger repression of ornithine decarboxylase activity. Ivospemin is promising for research of cancers .
Assay Types