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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
oxygen-induced
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "oxygen-induced" in MCE Product Catalog:
4
Category:
Monophenols Simple Phenylpropanols Phenols Dicerothamnus rhinocerotis Phenylpropanoids Plants Umbelliferae
Target:
4
4 Cited Publications
Synonyms: Triptycene-1,4-quinone
Research Areas:
INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 specifically blocks targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site and is an effective inhibitor of CN-NFAT signaling .
2
2 Cited Publications
Synonyms: Heptanedioic acid; 1,5-Pentanedicarboxylic acid; 1,7-Heptanedioic acid
Category:
Immune System Disorder Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-W127832
CAS No.: 123148-15-2
Cat. No.: HY-19720A
CAS No.: 1141934-97-5
Synonyms: ACU-4429 hydrochloride
Target:
Research Areas:
Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
Cat. No.: HY-P3226
CAS No.: 147819-32-7
Target:
Research Areas:
Target:
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Fluoflavine (ML-090) is a selective NOX1 inhibitor and reactive oxygen species inhibitor. Fluoflavine reduces reactive oxygen species production, NOX1-mediated downstream signaling events, and oxygen-glucose deprivation-induced retinal ganglion cell death. Fluoflavine inhibits NADPH oxidase activity and pathological retinal neovascularization induced by oxygen-induced retinopathy in the retinas of ischemic mice. Fluoflavine can be used in studies related to retinal ischemia-reperfusion injury and proliferative retinopathy .
Cat. No.: HY-19720
CAS No.: 1141777-14-1
Synonyms: ACU-4429
Target:
Research Areas:
Emixustat is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
Cat. No.: HY-117133
CAS No.: 1621332-91-9
Synonyms: SF0166
Target:
Research Areas:
Nesvategrast (SF0166) is a potent and selective αvβ3 antagonist with IC50 values of 0.6 nM, 8 nM, and 13 nM for αvβ3, αvβ6, and αvβ8, respectively. Nesvategrast inhibits cellular adhesion to vitronectin across human, rat, rabbit, and dog cell lines with IC50 values of 7.6 pM to 76 nM. Nesvategrast decreases neovascularization in the oxygen-induced retinopathy mouse model .
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Synonyms: (rac)-AR-13324 M1 metabolite
Research Areas:
(rac)-AR-13503 ((rac)-AR-13324 M1 metabolite) is the isoform of AR-13503 (HY-12798C). AR-13503 a ROCK/PKC inhibitor, inhibiting angiogenesis and enhancing retinal pigment epithelium (RPE) permeability. AR-13503 also inhibits the formation of aberrant neovascularization (NV) in oxygen-induced retinopathy (OIR) model in mice .
Cat. No.: HY-P4253A
Synonyms: H-Arg-Gln-OH TFA
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Research Areas:
Cat. No.: HY-108544R
CAS No.: 3519-82-2
Synonyms: Triptycene-1,4-quinone (Standard)
Research Areas:
INCA-6 (Standard) is the analytical standard of INCA-6 (HY-108544). This product is intended for research and analytical applications. INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 specifically blocks targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site and is an effective inhibitor of CN-NFAT signaling .
Cat. No.: HY-P992126
CAS No.: 3059389-31-7
Synonyms: EYE-103; MK-3000
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
