3059389-31-7
Chemical Structure
Remigromig
Synonym(s): EYE-103; MK-3000
- CAS No.: 3059389-31-7
- Formula:N/A
- Molecular Weight:(199.68 kDa)
SMILES: [Remigromig]
Biological Activity: Remigromig (EYE-103; MK-3000) is a humanized dual-target monoclonal antibody that targets LRP5 and FZD4. Remigromig activates the Wnt/β-catenin signaling pathway by mimicking the natural ligand Norrin, induces tight junction formation and restores blood-retinal barrier function. Administered via intravitreal injection, Remigromig reduces retinal vascular leakage, and demonstrates improvements in best-corrected visual acuity and reductions in retinal thickness in studies of diabetic macular edema. Remigromig can be used for research related to macular degeneration[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Remigromig | 95.25% | Remigromig (EYE-103; MK-3000) is a humanized dual-target monoclonal antibody that targets LRP5 and FZD4. Remigromig activates the Wnt/β-catenin signaling pathway by mimicking the natural ligand Norrin, induces tight junction formation and restores blood-retinal barrier function. Administered via intravitreal injection, Remigromig reduces retinal vascular leakage, and demonstrates improvements in best-corrected visual acuity and reductions in retinal thickness in studies of diabetic macular edema. Remigromig can be used for research related to macular degeneration. | ||||||||||||||||||||
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