48 Results for "

recurrent

" in MedChemExpress (MCE) Product Catalog:
Products (48)

48 Results for "recurrent" in MCE Product Catalog:

27
27 Publications Verification
Cat. No.: HY-10587
CAS No.: 935693-62-2
Purity:  98.44%
Research Areas:  

Cancer

BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells .
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27
27 Publications Verification
Cat. No.: HY-108239
CAS No.: 1392399-03-9
Research Areas:  

Cancer

BIX-01294 trihydrochloride is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 trihydrochloride inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294 trihydrochloride, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 trihydrochloride has antitumor activity in recurrent tumor cells .
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7
7 Cited Publications
Cat. No.: HY-P99032
CAS No.: 1228763-95-8
Synonyms: IPH2201
Monalizumab (IPH2201) is an immune checkpoint inhibitor targeting Natural Killer Group 2A (NKG2A). Monalizumab, a humanized anti-NKG2A blocking mAb, increases IFN-γ production, thereby promoting NK cell effector functions. Monalizumab can be used for the research of head and neck squamous cell carcinoma (HNSCC) .
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3
3 Cited Publications
Cat. No.: HY-B1402
CAS No.: 2203-97-6
Synonyms: Hydrocortisone 21-hemisuccinate
Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a glucocorticoid, is an orally active steroidal anti-inflammatory agent (SAID) with anti-inflammatory and immunomodulatory activities. Hydrocortisone hemisuccinate inhibits the bioactivity of IL-6 and IL-3 with IC50 values of 6.7 and 21.4 μM, respectively. Hydrocortisone hemisuccinate can be used in the study of ulcerative colitis (UC) and recurrent oral ulcers .
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3
3 Cited Publications
Cat. No.: HY-B1402A
CAS No.: 83784-20-7
Synonyms: Hydrocortisone 21-hemisuccinate hydrate
Hydrocortisone hemisuccinate hydrate (Hydrocortisone 21-hemisuccinate hydrate), a glucocorticoid, is an orally active steroidal anti-inflammatory agent (SAID) with anti-inflammatory and immunomodulatory activities. Hydrocortisone hemisuccinate hydrate inhibits the bioactivity of IL-6 and IL-3 with IC50 values of 6.7 and 21.4 μM, respectively. Hydrocortisone hemisuccinate hydrate can be used in the study of ulcerative colitis (UC) and recurrent oral ulcers .
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2
2 Cited Publications
Cat. No.: HY-109050
CAS No.: 1637771-14-2
Purity:  98.04%
Synonyms: GS-5829
Research Areas:  

Cancer

Alobresib (GS-5829) is a BET bromodomain inhibitor, which represents a highly effective therapeutics agent against recurrent/chemotherapy resistant uterine serous carcinoma (USC) overexpressing c-Myc. Alobresib can be used in the metastatic castration-resistant prostate cancer (mCRPC) research .
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1
1 Cited Publications
Cat. No.: HY-113315
CAS No.: 5255-17-4
Purity:  99.93%
3β-Hydroxy-5-cholenoic acid is a steroidal monohydroxy bile acid and serves as a substrate for sulfation reactions. It is applicable to the research of extrahepatic biliary atresia and recurrent intrahepatic cholestasis of pregnancy .
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1
1 Cited Publications
Cat. No.: HY-B0727
CAS No.: 2152-44-5
Synonyms: Betamethasone 17-valerate
Research Areas:  

Inflammation/Immunology

Betamethasone valerate (Betamethasone 17-valerate), the 17-valerate ester of Betamethasone, is a topical corticosteroid with anti-inflammatory activity. Betamethasone valerate is used in the treatment of recurrent aphthous stomatitis. Betamethasone valerate inhibits the binding of the radiolabeled glucocorticoid dexamethasone ( 3H dexamethasone) to human epidermis and mouse skin with IC50s of 5 and 6 nM, respectively .
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1
1 Cited Publications
Cat. No.: HY-P9929
CAS No.: 1246264-45-8
Synonyms: BLA761046; MBL-CDB1; MDX-1388

Target:  

Bacterial

Research Areas:  

Infection

Bezlotoxumab (BLA761046; MBL-CDB1; MDX-1388) is a fully humanized IgG1/kappa monoclonal antibody directed against Clostridium difficile toxin B. Bezlotoxumab mediates the early reconstitution of gut microbiota to reduce the risk of recurrent Clostridium difficile infection (CDI). Bezlotoxumab can be used for the study of recurrent Clostridium difficile infection prevention .
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1
1 Cited Publications
Cat. No.: HY-Y0588
CAS No.: 1148-11-4
Synonyms: L-Cbz-Proline
Target:  

MMP

Research Areas:  

Others

Carbobenzoxyproline (L-Cbz-Proline) is an inhibitor of prolidase. Carbobenzoxyproline can be used for prolidase deficiency (PD) research .
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Cat. No.: HY-P3004
CAS No.: 9025-37-0
Synonyms: Lyticase
Research Areas:  

Infection

Endo-1,3-β-glucanase (Lyticase) is an endoenzyme that can specifically cleave β-1,3-glycosidic bonds. Endo-1,3-β-glucanase recognizes and binds to β-1,3-glucan chains, catalyzing the cleavage of glycosidic bonds and hydrolyzing polysaccharides into oligosaccharides. Endo-1,3-β-glucanase eliminates vaginal Candida. Endo-1,3-β-glucanase can be used in the study of recurrent Candida vaginitis .
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Cat. No.: HY-P99948
CAS No.: 2329692-74-0
Synonyms: AMG-596

Target:  

EGFR CD3

Research Areas:  

Neurological Disease Cancer

Etevritamab (AMG-596) is a bispecific T-cell engager that targets EGFRvIII and CD3. Etevritamab simultaneously binds CD3 on T cells and EGFRvIII on glioblastoma multiforme cells, thereby forming a bridge structure. Etevritamab triggers T-cell activation, proliferation, secretion of cytotoxic substances, and tumor cell lysis. Etevritamab extends overall survival and induces tumor regression in mouse models of glioblastoma multiforme. Etevritamab can be used for research related to glioblastoma .
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Cat. No.: HY-P99262
CAS No.: 1430205-07-4
Synonyms: BAX69; Anti-Human MIF Recombinant Antibody

Research Areas:  

Cancer

Imalumab (BAX69) is a recombinant, human IgG1 monoclonal antibody that targets macrophage inhibitory factor (MIF). Imalumab can be used for the research of ovarian carcinoma, recurrent malignant ascites and cancer .
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Cat. No.: HY-P99768
CAS No.: 2095504-49-5
Synonyms: TTAC-0001; Tanibirumab

Target:  

VEGFR

Research Areas:  

Cancer

Olinvacimab (TTAC-0001) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab inhibits VEGF binds to KDR with a Kd value of 0.23 nM. Olinvacimab has antiangiogenic activity. Olinvacimab can be used for the research of recurrent glioblastoma and breast cancer .
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Cat. No.: HY-150306
CAS No.: 2305750-23-4
Purity:  99.94%
Synonyms: IM-250
Target:  

DNA/RNA Synthesis HSV

Research Areas:  

Infection

Adibelivir (IM-250) is an orally active helicase-primase inhibitor. Adibelivir is effective against HSV infection and reduces reactivation of latent HSV. Adibelivir inhibits HSV-1 infection in Vero cells (IC50: ~20 nM). Adibelivir can be used for the study of recurrent herpes disease[1][2].

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Cat. No.: HY-159768A
CAS No.: 2882922-68-9
DOTAGA.Glu.(FAPi) 2 is a FAPI homodimer in which a central glutamic acid (Glu) linker connects FAPI and a chelator. Radiolabeled with gallium- 68, lutetium- 177 or terbium- 161, DOTAGA.Glu.(FAPi) 2 is applicable to FAP-positive cancer PET imaging studies. DOTAGA.Glu.(FAPi) 2 is suitable for research related to prostate adenocarcinoma and recurrent glioblastoma multiforme .
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Cat. No.: HY-P99544
CAS No.: 2417649-97-7
Synonyms: HBM-9167; KL-A167

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Tagitanlimab (HBM-9167) is a humanized anti-PD-L1 antibody (IgG1κ type). Tagitanlimab selectively blocks the interaction of PD-L1 and PD-1. Tagitanlimab has the potential to be studied in recurrent or metastatic nasopharyngeal carcinoma (NPC) .
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Cat. No.: HY-P99594
CAS No.: 2305043-30-3
Synonyms: ZKAB001; STI-1014; STI-A1014

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Socazolimab (ZKAB001) is an anti-PD-L1 monoclonal antibody. Socazolimab has lasting safety and efficacy in the treatment of recurrent or metastatic cervical cancer. Socazolimab also has potential applications in small cell lung cancer, esophageal squamous cell carcinoma (ESCC), advanced urothelial carcinoma and osteosarcoma .
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Cat. No.: HY-P991143
CAS No.: 3018936-99-4
Synonyms: TORL-1-23 Antibody

Target:  

Claudin ADC Antibodies

Research Areas:  

Cancer

Ixotatug (TORL-1-23 Antibody) is a monoclonal antibody targeting claudin-6 (CLDN6) that serves as the antibody component of the ADC drug Ixotatug vedotin (TORL-1-23). Ixotatug is applicable to research related to various cancers including ovarian cancer .
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Cat. No.: HY-14743B
CAS No.: 1029401-59-9
Purity:  99.64%
Synonyms: SCV 07 hydrochloride; Gamma-D-glutamyl-L-tryptophan hydrochloride
Target:  

Bacterial STAT

Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod hydrochloride (SCV 07 hydrochloride) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod hydrochloride (SCV 07 hydrochloride) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .
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