3018936-99-4
Chemical Structure
Ixotatug
Synonym(s): TORL-1-23 Antibody
- CAS No.: 3018936-99-4
- Formula:N/A
- Molecular Weight:(145.032 kDa)
SMILES: N/A
Biological Activity: Ixotatug (TORL-1-23 Antibody) is a monoclonal antibody targeting claudin-6 (CLDN6) that serves as the antibody component of the ADC drug Ixotatug vedotin (TORL-1-23). Ixotatug is applicable to research related to various cancers including ovarian cancer[1][2].
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Ixotatug | 99% | Ixotatug (TORL-1-23 Antibody) is a monoclonal antibody targeting claudin-6 (CLDN6) that serves as the antibody component of the ADC drug Ixotatug vedotin (TORL-1-23). Ixotatug is applicable to research related to various cancers including ovarian cancer. | ||||||||||||||||||||
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- [1]. Lee J Y, et al. 14oP Preliminary safety and efficacy of ixotatug vedotin (TORL-1-23), a Claudin 6-targeted ADC, in combination with bevacizumab in recurrent ovarian cancer. Abstract, 2026, 11(Suppl 6): 108187.
- [2]. Konecny G E, et al. Initial results of dose finding in a first-in-human phase 1 study of a novel Claudin 6 (CLDN6) targeted antibody drug conjugate (ADC) TORL-1-23 in patients with advanced solid tumors. Journal of Clinical Oncology, 2023, 41(16_suppl): 3082.
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