46 Results for "

siderophore

" in MedChemExpress (MCE) Product Catalog:
Products (46)

46 Results for "siderophore" in MCE Product Catalog:

20
20 Cited Publications
Cat. No.: HY-17628
CAS No.: 1225208-94-5
Synonyms: S-649266
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Cefiderocol (S-649266) is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less.
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Cat. No.: HY-160238
CAS No.: 95536-41-7
Synonyms: Corynebactin
Target:  

Bacterial Fungal

Bacillibactin (Corynebactin) is a cyclic tricatecholate siderophore. Bacillibactin’s primary function is to facilitate bacterial iron acquisition by chelating iron ions (Fe 3+) from the environment, thereby aiding bacterial survival under iron-limited conditions. Bacillibactin exhibits direct antimicrobial activity, such as inhibition of the growth of the producing bacteria Pseudomonas aeruginosa and Aeromonas veronae, as well as plant pathogens such as Pseudomonas syringae.Bacillibactin can be used in antibacterial and antifungal research .
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Cat. No.: HY-132989
CAS No.: 1638156-31-6
Purity:  ≥95.0%
Mal-Deferoxamine is a maleimide-functionalized trihydroxamate siderophore derivative that can be isolated from Streptomyces pilosus. Mal-Deferoxamine possesses highly specific Fe (III) chelating ability, and the stability of complexes formed between it and non-Fe (III) metal ions is significantly lower. Mal-Deferoxamine exhibits growth inhibitory effects against Gram-positive bacteria, but shows no obvious inhibitory activity against Gram-negative bacteria (MIC>50 μM). Mal-Deferoxamine is mainly suitable for scientific research in hematology and related fields .
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Cat. No.: HY-128525
CAS No.: 28384-96-5
Purity:  98.82%
Enterobactin is a siderophore produced by Gram-negative bacteria and has an extremely high affinity for iron. During the process of Salmonella typhimurium infecting macrophages, Enterobactin can not only help bacteria uptake iron but also reduce the antibacterial activity of macrophages. In addition, Enterobactin is also involved in the oxidative stress response of Escherichia coli. Enterobactin can be hydrolyzed by Fes in the cell and exert antioxidant effects by scavenging free radicals .
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Cat. No.: HY-135498
CAS No.: 20008-20-2
Target:  

Bacterial

Research Areas:  

Infection

Ferrioxamine E is a siderophore and bacterial growth regulator. Ferrioxamine E can chelate ferric iron, and promote the growth, morphological differentiation and antibiotic synthesis of Streptomyces tanashiensis .
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Cat. No.: HY-N11874
CAS No.: 127902-98-1
Staphyloferrin A is a carboxylate-type siderophore, as well as an iron (III) chelator and a HtsA ligand with high binding affinity for iron (III). Staphyloferrin A can be used in studies of bacterial infections .
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Cat. No.: HY-122280
CAS No.: 26198-65-2
Purity:  97.23%
Aerobactin is a siderophore produced by bacteria. Aerobactin is a highly potent pathogenic factor .
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Cat. No.: HY-W013673
CAS No.: 1482-97-9
2,3-Diaminopropionic acid hydrochloride is the precursor of antibiotics and the siderophore staphyloferrin B. 2,3-Diaminopropionic acid hydrochloride is the inhibitor for polyphenoloxidase (PPO) .
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Cat. No.: HY-123648
CAS No.: 138846-62-5
Purity:  99.10%
Target:  

Others

Rhizoferrin is a siderophore, which can be isolated from Rhizopus microsporus. Rhizoferrin binds iron ions with high affinity, and can be used as an effective iron source .
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Cat. No.: HY-19882
CAS No.: 941285-15-0
Target:  

Bacterial

Research Areas:  

Infection

BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively .
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Cat. No.: HY-145301
CAS No.: 65840-95-1
Target:  

Bacterial

Research Areas:  

Infection

Mycobactin-IN-1, a pyrazoline analogue, is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-1 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway. Mycobactin-IN-1 inhibits whole-cell drug efflux pumps in M. smegmatis. Mycobactin-IN-1 eradicates intracellularly surviving mycobacteria. Mycobactin-IN-1 shows an excellent in vivo pharmacokinetic profile. Mycobactin-IN-1 can be used for the research of tuberculosis .
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Cat. No.: HY-124452
CAS No.: 26605-16-3
Purity:  95.00%
Synonyms: Desferrioxamine E; Nocardamin
Nocardamine (Desferrioxamine E; Nocardamin) is a cyclic trihydroxamate siderophore with iron ion chelation, antioxidant, antibacterial and other activities. Nocardamine is synthesized by Pseudomonas stutzeri under iron-deficient conditions, and excessive iron ions significantly inhibit its biosynthesis process. Nocardamine increases the level of phosphorylated ERK protein, promotes nuclear translocation of β-catenin, and restores the downregulated expression of SIRT1 protein. Nocardamine alleviates cellular oxidative stress, reduces ROS content, and simultaneously repairs the ability to form mineralized nodules and the expression of osteogenic markers. Nocardamine induces FoxA gene transcription and protein expression to assist Pseudomonas aeruginosa in iron ion uptake; it also selectively inhibits the proliferation of mycobacteria. Nocardamine induces spindle-shaped morphological changes in BM-N4 insect cells, and sufficient iron ions inhibit this cellular morphological change. Nocardamine is suitable for research related to bacterial infections .
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Cat. No.: HY-N13871
CAS No.: 104245-09-2
Anguibactin is an antibiotic that acts as a siderophore. Anguibactin has a strong affinity with Fe 3+ .
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Cat. No.: HY-113379
CAS No.: 4033-39-0
2,3-Diaminopropionic acid is the precursor of antibiotics and the siderophore staphyloferrin B. 2,3-Diaminopropionic acid is the inhibitor for polyphenoloxidase (PPO) .
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Cat. No.: HY-122280R
CAS No.: 26198-65-2
Calcium gluconate (Standard) is the analytical standard of Calcium gluconate. This product is intended for research and analytical applications. Calcium Gluconate Monohydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-124237
CAS No.: 106983-30-6
Purity:  99.17%
Target:  

Bacterial

Research Areas:  

Others

N-Octanoyl-DL-homoserine lactone is a member of N-acyl homoserine lactones (AHLs) family, also one of the signal molecule of quorum-sensing (QS) signals. N-Octanoyl-DL-homoserine lactone can regulate the production of siderophores and present positive correlation in Aeromonas sobria strain AS7. N-Octanoyl-DL-homoserine lactone can also regulate the secretion of proteases and stimulate the production of total volatile basic nitrogen (TVB-N) .
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Cat. No.: HY-122395
CAS No.: 77165-75-4
Triornicin is a siderophore. Triornicin can be used in cancer research .
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Cat. No.: HY-N14935
CAS No.: 70393-50-9
Agrobactin is a catechol-type siderophore (microbial iron transport compound) .
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Cat. No.: HY-129580
CAS No.: 133705-27-8
Category:  

Microorganisms Antibiotics

Target:  

Bacterial Fungal

Nannochelin B is a novel citrate-hydroxamate siderophore with a growth-inhibitory activity against some bacteria and fungi .
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Cat. No.: HY-N16461
CAS No.: 12676-10-7
Category:  

Microorganisms Antibiotics

Target:  

Bacterial

Albomycin ε is a siderophore-antibiotic conjugate targeting bacterial ribosomes (MIC values:>512 μg/mL). Albomycin ε is promising for research of Streptococcus pneumoniae and Staphylococcus aureus infections .
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