Albomycin ε
Albomycin ε is a siderophore-antibiotic conjugate targeting bacterial ribosomes (MIC values:>512 μg/mL). Albomycin ε is promising for research of Streptococcus pneumoniae and Staphylococcus aureus infections.
For research use only. We do not sell to patients.
- CAS No.: 12676-10-7
- Formula: C36H56FeN11O17S
- Molecular Weight:1002.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 12676-10-7
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Molecular Weight 1002.80
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Formula C36H56FeN11O17S
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SMILES
O[C@H]1[C@H](O)[C@@H](N2C=CC(N(C)C2=O)=N)S[C@@]1([H])[C@H](O)[C@@H](C(O)=O)NC([C@H](CO)NC([C@@H](N3)CCCN(C(C)=O4)O[Fe]546(O7)ON(C(C)=O6)CCC[C@H](NC([C@H](CCCN7C(C)=O5)N)=O)C3=O)=O)=O
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Structure Classification
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Initial Source
Streptomyces sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Lin Z, et al. Total synthesis and antimicrobial evaluation of natural albomycins against clinical pathogens. Nat Commun. 2018 Sep 4;9(1):3445. [Content Brief]
[2]. Gadakh B, et al. Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase. Bioorg Med Chem. 2020 Sep 1;28(17):115645. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)