28384-96-5
Chemical Structure
Enterobactin
- CAS No.: 28384-96-5
- Formula:C30H27N3O15
- Molecular Weight:669.55
IUPAC Name: N,N',N''-((3S,7S,11S)-2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl)tris(2,3-dihydroxybenzamide)
InChIKey: SERBHKJMVBATSJ-BZSNNMDCSA-N
SMILES: O=C1OC[C@H](NC(C2=CC=CC(O)=C2O)=O)C(OC[C@H](NC(C3=CC=CC(O)=C3O)=O)C(OC[C@@H]1NC(C4=CC=CC(O)=C4O)=O)=O)=O
Biological Activity: Enterobactin is a siderophore produced by Gram-negative bacteria and has an extremely high affinity for iron. During the process of Salmonella typhimurium infecting macrophages, Enterobactin can not only help bacteria uptake iron but also reduce the antibacterial activity of macrophages. In addition, Enterobactin is also involved in the oxidative stress response of Escherichia coli. Enterobactin can be hydrolyzed by Fes in the cell and exert antioxidant effects by scavenging free radicals[1][2].
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Enterobactin | 98.02% | Enterobactin is a siderophore produced by Gram-negative bacteria and has an extremely high affinity for iron. During the process of Salmonella typhimurium infecting macrophages, Enterobactin can not only help bacteria uptake iron but also reduce the antibacterial activity of macrophages. In addition, Enterobactin is also involved in the oxidative stress response of Escherichia coli. Enterobactin can be hydrolyzed by Fes in the cell and exert antioxidant effects by scavenging free radicals. | ||||||||||||||||||||
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Enterobactin (Standard) | ≥98% | Enterobactin (Standard) is the analytical standard of Enterobactin. This product is intended for research and analytical applications. Enterobactin is a siderophore produced by Gram-negative bacteria and has an extremely high affinity for iron. During the process of Salmonella typhimurium infecting macrophages, Enterobactin can not only help bacteria uptake iron but also reduce the antibacterial activity of macrophages. In addition, Enterobactin is also involved in the oxidative stress response of Escherichia coli. Enterobactin can be hydrolyzed by Fes in the cell and exert antioxidant effects by scavenging free radicals. | ||||||||||||||||||||
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- [1]. Saha P, et al. The bacterial siderophore enterobactin confers survival advantage to Salmonella in macrophages. Gut Microbes. 2019;10(3):412-423. [Content Brief]
- [2]. Peralta DR, et al. Enterobactin as Part of the Oxidative Stress Response Repertoire. PLoS One. 2016 Jun 16;11(6):e0157799. [Content Brief]
Keywords