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66

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6

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11

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25

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1

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Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-NP008
    β-Lactoglobulin

    		Lipocalin Family Inflammation/Immunology
    β-Lactoglobulin, a major whey protein, is a small globular protein from the lipocalin family. β-Lactoglobulin is an important source of the essential and branched-chain amino acids (leucine, isoleucine, and valine). β-Lactoglobulin shows antioxidant properties, because it contains two disulfide bonds and one free thiol group. β-Lactoglobulin is a ligand transport agent. β-Lactoglobulin is one of the major allergens in milk and can be utilized in the research for developing safe hypoallergenic dairy products .
    β-Lactoglobulin
  • HY-D0874
    HEPPSO

    		Biochemical Assay Reagents Others
    HEPPSO is a zwitterionic Good's buffer suitable for physiological pH conditions. HEPPSO forms high-order oligomers in aqueous solutions and can form a 1:1 complex with Cu 2+ via its hydroxyalkyl and tertiary amine groups. However, HEPPSO contains a structurally similar trace impurity lacking an alkanesulfonic acid side chain. The complex formed by this impurity and Cu 2+ has a very low Ka; therefore, HEPPSO may interfere with studies on copper speciation analysis in natural water bodies .
    HEPPSO
  • HY-W012725
    2,4-Difluorophenol

    		Biochemical Assay Reagents Drug Intermediate Others
    2,4-Difluorophenol is a difluoro-substituted phenol that serves as a starting material for the synthesis of 4,6-difluoro-5,7-dihydroxytryptamine .
    2,4-Difluorophenol
  • HY-P10486
    AIP-II

    		Bacterial Infection
    AIP-II is a cyclic peptide signaling molecule for quorum sensing, which is produced by Staphylococcus aureus. AIP-II potently inhibits AgrC-III in Methicillin (HY-121544)-resistant type III Staphylococcus aureus strain AH1747, with an IC50 of 0.532 nM. AIP-II binds to the AgrC-II receptor and regulates virulence gene expression in Staphylococcus aureus .
    AIP-II
  • HY-W016371
    3,4,5-Trichloropyridine

    3,4,5-threechlorine pyridine

    		 Biochemical Assay Reagents Others
    3,4,5-Trichloropyridine is a chlorinated pyridine compound and also serves as an internal standard for quantitative proton nuclear magnetic resonance spectroscopy .
    3,4,5-Trichloropyridine
  • HY-W034674
    Silver diethyldithiocarbamate

    Silver(1+) diethyldithiocarbamate

    		 Biochemical Assay Reagents Others
    Silver diethyldithiocarbamate (SDDC) is an organic compound consisting of silver ions complexed with the ligand diethyldithiocarbamate. SDDC is mainly used as a reagent in analytical chemistry to detect the presence of copper, iron and other heavy metals in various materials. It acts as a chelating agent, binding to metal ions and forming stable complexes that can be easily analyzed using techniques such as UV-Vis spectroscopy.
    Silver diethyldithiocarbamate
  • HY-137855
    4-Methylumbelliferyl sulfate potassium

    		Biochemical Assay Reagents Others
    4-Methylumbelliferyl sulfate (potassium), a fluorescent substrate, is commonly used to detect sulfatase activity in biochemical and biomedical research. It consists of a sulfate group attached to a fluorescent molecule, which can be cleaved by sulfatase enzymes. Upon cleavage, 4-Methylumbelliferyl sulfate releases a highly fluorescent product that can be detected using fluorescence microscopy or spectroscopy. The use of 4-Methylumbelliferyl sulfate as a substrate for sulfatase enzymes allows accurate detection and quantification of these enzymes in a variety of biological samples.
    4-Methylumbelliferyl sulfate potassium
  • HY-128747A
    α-D-Glucose-1-phosphate disodium hydrate

    		Drug Derivative Drug Intermediate Antibiotic Cardiovascular Disease Inflammation/Immunology
    α-D-Glucose-1-phosphate disodium hydrate is a derivative of D-glucose (HY-B0389). α-D-Glucose-1-phosphate disodium hydrate serves as a starting material for glucuronic acid synthesis. Glucuronic acid acts as a Ca 2+ chelator and also functions as a biosynthetic substrate for the production of linear maltooligosaccharides or α,α-trehalose. α-D-Glucose-1-phosphate disodium hydrate can be used as a cytostatic compound, Antibiotic, and immunosuppressant essential for heart disease management. α-D-Glucose-1-phosphate disodium hydrate is applicable to the research of heart disease .
    α-D-Glucose-1-phosphate disodium hydrate
  • HY-W016510
    Benzenesulfonate sodium

    		Biochemical Assay Reagents Drug Intermediate Others
    Benzenesulfonate sodium is the sodium salt of Benzenesulfonic acid. Benzenesulfonate sodium facilitates the identification of -SO3H and -SO3 - vibrational bands in compounds in Raman spectroscopy. Benzenesulfonate sodium was used in the synthesis of 1-Butyl-3-propanenitrile imidazolium benzenesulfonate [C2CN Bim]BS .
    Benzenesulfonate sodium
  • HY-D0303A
    Chrysoidine G

    Solvent Orange 3 hydrochloride

    		 Fluorescent Dye Others
    Chrysoidine G (Solvent Orange 3 hydrochloride) is an industrial azoic dye (cationic dye). Chrysoidine G (Solvent Orange 3 hydrochloride) is used for the construction of most textile dyestuffs and also in synthetic industrial compounds. Chrysoidine G (Solvent Orange 3 hydrochloride) concentration can be determined by UV-Vis spectroscopy .
    Chrysoidine G
  • HY-129242
    Tempone

    4-Oxo-Tempo

    		 SOD Others
    Tempone (4-Oxo-Tempo) is a stable water-soluble nitro radical. Tempone is widely used as a contrast agent for metabolic activity and hypoxic sensitivity in electron spin resonance spectroscopy, magnetic resonance imaging and dynamic nuclear polarization. Tempone reduces superoxide radicals by mimicking the activity of superoxide dismutase (SOD), thereby reducing the formation of hydroxyl radicals and peroxynitrites. Tempone can be used in the study of ischemia-reperfusion injury and acute renal failure .
    Tempone
  • HY-W004048
    Sodium 4-methylbenzenesulfonate

    Sodium p-toluenesulfonate

    		 Environmental Pollutants Drug Intermediate Others
    Sodium 4-methylbenzenesulfonate (Sodium p-toluenesulfonate) is a drug intermediate, capable of being used to synthesize xanthine oxidase inhibitors. Sodium 4-methylbenzenesulfonate can be used as a dopant to construct a polypyrrole (PPy) conductive film on the surface of titanium (Ti) implants .
    Sodium 4-methylbenzenesulfonate
  • HY-75070
    (+)-1-(1-Naphthyl)ethylamine

    		Biochemical Assay Reagents Others
    (+)-1-(1-Naphthyl)ethylamine ((+)-1-(1-NEA)) is a chiral modifier used to introduce enantioselectivity in catalytic hydrogenation reactions. 1-NEA can undergo H-D exchange with D2 in solution to form N?D bonds. That is, 1-NEA can complete Pt surface adsorption and protonation through amine N atoms, indicating that NEA molecules have the potential to impart enantioselectivity to Pt hydrogenation catalysts .
    (+)-1-(1-Naphthyl)ethylamine
  • HY-N8215
    Achyranthoside C

    		Drug Intermediate Others
    Achyranthoside C is a triterpenoid saponin found in the roots of Achyranthese bidentata Bl. .
    Achyranthoside C
  • HY-W004078
    4-Hydroxybenzylamine

    		Endogenous Metabolite Metabolic Disease
    4-Hydroxybenzylamine is a natural biogenic amine. 4-Hydroxybenzylamine can be produced through the breakdown metabolism of glucosinolates, with glutamine serving as the non-classical ammonia donor. 4-Hydroxybenzylamine can be utilized for the study of plant amine biosynthesis .
    4-Hydroxybenzylamine
  • HY-131682
    3-C6-NBD-cholesterol

    3-Hexanoyl-NBD-cholesterol

    		 Fluorescent Dye Others
    3-C6-NBD-cholesterol is a fluorescent analog of Chol that can be used to measure the kinetics of membrane and intracellular trafficking .
    3-C6-NBD-cholesterol
  • HY-W011607
    L-Alanyl-L-tryptophan

    		Amino Acid Derivatives Others
    L-Alanyl-L-tryptophan is a dipeptide formed from L-alanyl and L-tryptophan, and is also a metabolite. L-Alanyl-L-tryptophan can be adsorbated on the surface of gold nanoparticles, and the Raman signal can be enhanced by SERS technology to obtain the enhanced Raman spectroscopy .
    L-Alanyl-L-tryptophan
  • HY-W033573
    Hexaammineruthenium(II) chloride

    		Biochemical Assay Reagents Others
    Hexaammineruthenium(II) chloride is a non-corrosive redox probe. Hexaammineruthenium(II) chloride avoids gold electrode corrosion and degradation to enable stable electrochemical impedance spectroscopy measurements. Hexaammineruthenium(II) chloride supports detection of human-IgG with a defined diagnostic concentration range .
    Hexaammineruthenium(II) chloride
  • HY-D1240
    Rhodamine 101 inner salt

    		Biochemical Assay Reagents Others
    Rhodamine 101 inner salt is a bright fluorescent dye with excitation and emission maxima at 565 and 595 nm, respectively. It can be used in various biological applications such as fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy, and ELISA.
    Rhodamine 101 inner salt
  • HY-W012911
    2,6-Difluoropyridine

    		Biochemical Assay Reagents Others
    2,6-Difluoropyridine is a fluorinated pyridine derivative. 2,6-Difluoropyridine adopts a planar conformation in its S0 electronic ground state and S1(π,π) excited state .
    2,6-Difluoropyridine
  • HY-N4012
    Indole-3-glyoxylamide

    3-Indoleglyoxamide

    		 Others Others
    Indole-3-glyoxylamide (Compound 4) is a type of indole alkaloid. Indole-3-glyoxylamide shows no significant cytotoxic activity against Hela, Ishikawa, and MGC-803 cells .
    Indole-3-glyoxylamide
  • HY-N1156
    Thevetin B

    		Others Others
    Thevetin B (compound 1) is a betalain isolated from Thevetia peruviana .
    Thevetin B
  • HY-D1993
    ATTO 647 NHS ester

    		Fluorescent Dye HIV Infection
    ATTO 647 NHS ester is a fluorescent label targeting free amino groups. ATTO 647 NHS ester can undergo a nucleophilic reaction with the free amino groups of EF-C peptide via its activated carboxylic acid group to form a stable covalent conjugate. ATTO 647 NHS ester-labeled nanofibers not only retain retroviral transduction-enhancing activity but also maintain stable fluorescent signals in both buffer and cell culture systems. ATTO 647 NHS ester is suitable for detection applications including fluorescence spectroscopy, microscopy and flow cytometry. ATTO 647 NHS ester has been used in studies related to HIV-1 infection .
    ATTO 647 NHS ester
  • HY-Y0661
    4-Methylbenzyl cyanide

    		Biochemical Assay Reagents Others
    4-Methylbenzyl cyanide is an organic chemical probe used to study intramolecular rotation properties. 4-Methylbenzyl cyanide is promising for research of NMR spectroscopy and physical chemistry research on molecular dynamics .
    4-Methylbenzyl cyanide
  • HY-W131302
    Ethylenediaminediacetic acid

    N,N-Ethylenediglycine

    		 Endogenous Metabolite Cancer
    Ethylenediaminediacetic acid (N,N-Ethylenediglycine) is an important ligand that enhances the antiproliferative activity of metal complexes. The complexes formed by ethylenediacetic acid and metal ions exhibited significant antiproliferative properties in MCF-7 cancer cell line. The metal complexes of ethylenediacetic acid were able to interact with DNA and were studied by CD and EPR spectroscopy techniques. Ethylenediaminediacetic acid and its metal complexes were able to induce cell cycle arrest at the G(0)/G(1) phase. The crystal structure analysis of ethylenediacetic acid provided important structural information for understanding its biological activity .
    Ethylenediaminediacetic acid
  • HY-N16587
    Dehydro-γ-tocopherol

    		Others Inflammation/Immunology
    Dehydro-γ-tocopherol is a naturally occurring chromanol compound found in the Stemona, and it exhibits significant antioxidant activity .
    Dehydro-γ-tocopherol
  • HY-W017590
    m-Fluoronitrobenzene

    1-Fluoro-3-nitrobenzene; 3-Fluoronitrobenzene; m-FNBZ

    		 Drug Derivative Others
    m-Fluoronitrobenzene (1-Fluoro-3-nitrobenzene) is a meta-substituted benzene derivative bearing fluoro and nitro functional groups. m-Fluoronitrobenzene finds applications in the fields of pharmaceuticals, dyes, pesticides, and synthetic rubber .
    m-Fluoronitrobenzene
  • HY-N16580
    (+)-Lariciresinol 9′-p-coumarate

    		Others Cancer
    (+)-Lariciresinol 9′-p-Coumarate is a type of lignan. (+)-Lariciresinol 9′-p-Coumarate exhibits inhibitory activity against leukemia and other tumor cell lines .
    (+)-Lariciresinol 9′-p-coumarate
  • HY-N16836
    Diplomorphanin A

    Farrerol 4',7-di-O-β-D-glucopyranoside

    		 Others Others
    Diplomorphanin A (Farrerol 4',7-di-O-β-D-glucopyranoside) is a C-methylated flavonoid compound that can be found in Diplomorpha canescens. Diplomorpha canescens exhibits anti-tumor activity .
    Diplomorphanin A
  • HY-W176465
    BTA-2

    		Amyloid-β Others
    BTA-2, a benzothiazole dye, is structurally similar to thioflavin T (ThT), which exhibits an enhanced fluorescence signal when bound to amyloid fibrils. BTA-2 has distinct absorption and emission characteristics in solution and when bound to amyloid fibrils, which makes it can used for identifying amyloid fibrils using spectroscopy .
    BTA-2
  • HY-120410
    DL-4662

    		Biochemical Assay Reagents Neurological Disease
    DL-4662 is a 3,4-dimethoxy derivative that can be identified using techniques such as, GC-EI-MS, LC-tandem mass spectrometry and NMR spectroscopy .
    DL-4662
  • HY-W777072
    4-Isocyanato-TEMPO,Technical grade

    		HIV Others
    4-isocyanato TEMPO is a spin labeling reagent used to label the 2’-position in RNA. It has been used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by electron paramagnetic resonance (EPR) spectroscopy.
    4-Isocyanato-TEMPO,Technical grade
  • HY-D2757
    5(6)-Carboxyrhodamine 110 NHS ester

    		Fluorescent Dye Others
    5(6)-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. The conjugates of this dye often used for Fluorescence Correlation Spectroscopy (FCS).
    5(6)-Carboxyrhodamine 110 NHS ester
  • HY-111333
    Pyrroxamycin

    Dioxapyrrolomycin; LL-F42248α; AL-R2081

    		 Bacterial Infection
    Pyrroxamycin is a novel antibiotic produced by Streptomyces, whose chemical structure was determined by chemical properties and X-ray crystallography and 13C NMR spectroscopy analysis. It is active against Gram-positive bacteria and dermatophytes. In this paper, the authors discuss the taxonomy, fermentation, isolation, physicochemical properties, chemical structure, and biological activity of the strain producing Pyrroxamycin.
    Pyrroxamycin
  • HY-W016510R
    Benzenesulfonate sodium (Standard)

    		Reference Standards Biochemical Assay Reagents Drug Intermediate Others
    Benzenesulfonate (sodium) (Standard) is an analytical standard for Benzenesulfonate sodium (HY-W016510). This product is intended for research and analytical applications. Benzenesulfonate sodium is the sodium salt of Benzenesulfonic acid. Benzenesulfonate sodium facilitates the identification of -SO3H and -SO3 - vibrational bands in compounds in Raman spectroscopy. Benzenesulfonate sodium was used in the synthesis of 1-Butyl-3-propanenitrile imidazolium benzenesulfonate [C2CN Bim]BS .
    Benzenesulfonate sodium (Standard)
  • HY-D2230
    Cy3.5 alkyne

    		Fluorescent Dye Others
    Cy3.5 alkyne, a fluorescent dye, is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Cy3.5 alkyne can be used for the detection and labeling of azide-containing molecules/ biomolecules with fluorescence spectroscopy after azide-alkyne cycloaddition .
    Cy3.5 alkyne
  • HY-D0303AR
    Chrysoidine G (Standard)

    Solvent Orange 3 hydrochloride (Standard)

    		 Fluorescent Dye Reference Standards Others
    Chrysoidine G (Standard) is the analytical standard of Chrysoidine G. This product is intended for research and analytical applications. Chrysoidine G (Solvent Orange 3 hydrochloride) is an industrial azoic dye (cationic dye). Chrysoidine G (Solvent Orange 3 hydrochloride) is used for the construction of most textile dyestuffs and also in synthetic industrial compounds. Chrysoidine G (Solvent Orange 3 hydrochloride) concentration can be determined by UV-Vis spectroscopy .
    Chrysoidine G (Standard)
  • HY-119387
    Chevalone B

    		Bacterial Infection
    Chevalone B was isolated from the ethyl acetate extract of the marine sponge-associated fungus Aspergillus similanensis. The structure of Chevalone B was confirmed by 1D and 2D NMR spectroscopy. Chevalone B showed antimicrobial activity against Gram-positive and Gram-negative bacteria, Candida albicans, and multidrug-resistant strains from the environment. Studies on Chevalone B have shown its potential value in antimicrobial applications.
    Chevalone B
  • HY-N12964
    4-Hydroxycanthin-6-one

    		Others Others
    4-Hydroxycanthin-6-one is a novel quinoline alkaloid isolated from the stem bark of the tree Ailanthus altissima. Five other known compounds were also found in the study. The structures of the new compounds were determined by interpretation of physical and spectroscopic data, and their absolute configurations were determined by electronic circular dichroism spectroscopy and quantum chemical calculations. These compounds showed significant inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, showing potential anti-inflammatory properties .
    4-Hydroxycanthin-6-one
  • HY-N9900
    Demethyldaphnoretin-7-O-glucoside

    Demethyldaphnoretin-7-O-β-D-glucopyranoside

    		 Others Others
    Demethyldaphnoretin-7-O-β-Dglucopyranoside (Demethyldaphnoretin-7-O-glucoside)(compound 1) is a natural product isolated from the ethyl acetate fraction of the roots of Daphne oleoides .
    Demethyldaphnoretin-7-O-glucoside
  • HY-118626
    PD-254552

    		MEK p38 MAPK Cancer
    PD-254552 is a MEK inhibitor. PD-254552 exhibits hepatotoxicity and gastrointestinal toxicity in mice .
    PD-254552
  • HY-156731
    (8R,8'R)-Matairesinol 4,4'-di-O-β-D-glucopyranoside

    		Others Others
    (8R,8'R)-Matairesinol 4,4'-di-O-β-D-glucopyranoside (MDG) is a natural product isolated from Trachelospermum asiaticum .
    (8R,8'R)-Matairesinol 4,4'-di-O-β-D-glucopyranoside
  • HY-111297
    BMVC4

    		Biochemical Assay Reagents Cancer
    BMVC4 is a G-quadruplex (G4) stabilizer of the human telomeric sequence d[AG3(T2AG3)3]. Screening by circular dichroism (CD) spectroscopy revealed that BMVC4 is more suitable as the core molecule of G4 stabilizers than BMVC. The results showed that BMVC4-12C and BMVC4-8C3O are better candidates for G4 stabilizers and are worthy of further study. A simple and rapid screening method based on Cu2+-induced G4 unfolding can be used to find better G4 stabilizers for potential anticancer applications. CD results showed that the trivalent cations of 9-substituted BMVC derivatives are more suitable as G4 stabilizers than the divalent cations of BMVC. In addition, by monitoring the disappearance of the 291 nm CD band of human telomeres after Cu2+ addition, it was found that the core molecule of G4 stabilizer BMVC4 has better stability.
    BMVC4
  • HY-116156
    SR-4554

    		Biochemical Assay Reagents Cancer
    SR-4554 is a probe for the measurement of tumor hypoxia. SR-4554 undergoes enzymatic single-electron reduction reactions within hypoxic cells. SR-4554 determines the 19F retention index for four commonly used mouse tumors (EMT6, SCCVII, KILT and RIF-I) through 19F MRS technique. SR-4554 can used to detect tumor Hypoxia noninvasively by 19F magnetic resonance spectroscopy ( 19F MRS) .
    SR-4554
  • HY-179762
    16:0 Tempo PC

    		Others Metabolic Disease
    16:0 Tempo PC is a phosphocholine with a TEMPO group. (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) is commonly used as a spin-label for lipid membrane studies. TEMPO alwayss acts as a spin probe are in electron resonance spectroscopy, as a paramagnetic contrast agent in NMR, and as oxygen-sensitive probes in biological systems.
    16:0 Tempo PC
  • HY-179880
    16:0-18:1 Tempo PC

    		Others Metabolic Disease
    16:0-18:1 Tempo PC is a phosphocholine with a TEMPO group. (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) is commonly used as a spin-label for lipid membrane studies. TEMPO alwayss acts as a spin probe are in electron resonance spectroscopy, as a paramagnetic contrast agent in NMR, and as oxygen-sensitive probes in biological systems.
    16:0-18:1 Tempo PC
  • HY-117925
    Personalised postprandial-targeting

    		HBV Others
    Personalised postprandial-targeting is a way to modulate water-heme interactions with activity against low-spin P450 complexes. Personalised postprandial-targeting is able to maintain the axial water ligands of CYP2C9 even in the presence of inhibitors. Personalised postprandial-targeting also allows the hydrogen atoms of the axial water ligands to be observed by EPR spectroscopy, providing insights into the enzyme active site .
    Personalised postprandial-targeting
  • HY-D0303AS
    Chrysoidine G-d5 hydrochloride

    Solvent Orange 3-d5 hydrochloride

    		 Isotope-Labeled Compounds Fluorescent Dye Others
    Chrysoidine G-d5 hydrochloride (Solvent Orange 3-d5 hydrochloride) is the deuterium labeled Chrysoidine G (HY-D0303A). Chrysoidine G (Solvent Orange 3 hydrochloride) is an industrial azoic dye (cationic dye). Chrysoidine G (Solvent Orange 3 hydrochloride) is used for the construction of most textile dyestuffs and also in synthetic industrial compounds. Chrysoidine G (Solvent Orange 3 hydrochloride) concentration can be determined by UV-Vis spectroscopy .
    Chrysoidine G-d5 hydrochloride
  • HY-N17981
    (-)-Isorhamnetin 3-O-robinobioside

    		Drug Derivative Others
    (-)-Isorhamnetin 3-O-robinobioside (compound 6) is a flavonol glycoside. (-)-Isorhamnetin 3-O-robinobioside can be found in the aerial parts of Anthyllis sericea (Leguminosae) .
    (-)-Isorhamnetin 3-O-robinobioside
  • HY-N18181
    Tamarixetin 7-O-rutinoside

    		Others Others
    Tamarixetin 7-O-rutinoside is a flavonoid glycoside found in the flowers of Verbascum phlomoides L. .
    Tamarixetin 7-O-rutinoside

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