3,4,5-Trichloropyridine
Based on 1 Customer Validation
3,4,5-Trichloropyridine is a chlorinated pyridine compound and also serves as an internal standard for quantitative proton nuclear magnetic resonance spectroscopy.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 33216-52-3
- Formula: C5H2Cl3N
- Molecular Weight:182.44
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
3,4,5-Trichloropyridine serves as an internal standard for quantitative proton nuclear magnetic resonance spectroscopy, and can be used for the quantitative determination of lipophilic ketones in fresh roots of Salvia miltiorrhiza Bunge[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 33216-52-3
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Appearance Solid
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Molecular Weight 182.44
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Formula C5H2Cl3N
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Color White to off-white
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SMILES
C1=NC=C(C(=C1Cl)Cl)Cl
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Synonyms
3,4,5-threechlorine pyridine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (548.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (310 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Li Y, et al. Quantitative Determination and Validation of Four Ketones in Salvia miltiorrhiza Bunge Using Quantitative Proton Nuclear Magnetic Resonance Spectroscopy. Molecules. 2020 Apr 28;25(9):2043. [Content Brief]
[2]. Yao QJ, et al. Enantio- and Regioselective Electrooxidative Cobalt-Catalyzed C-H/N-H Annulation with Alkenes. Angew Chem Int Ed Engl. 2023 Mar 6;62(11):e202218533. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 5.4813 mL | 27.4063 mL | 54.8125 mL | 137.0314 mL |
| 5 mM | 1.0963 mL | 5.4813 mL | 10.9625 mL | 27.4063 mL | |
| 10 mM | 0.5481 mL | 2.7406 mL | 5.4813 mL | 13.7031 mL | |
| 15 mM | 0.3654 mL | 1.8271 mL | 3.6542 mL | 9.1354 mL | |
| 20 mM | 0.2741 mL | 1.3703 mL | 2.7406 mL | 6.8516 mL | |
| 25 mM | 0.2193 mL | 1.0963 mL | 2.1925 mL | 5.4813 mL | |
| 30 mM | 0.1827 mL | 0.9135 mL | 1.8271 mL | 4.5677 mL | |
| 40 mM | 0.1370 mL | 0.6852 mL | 1.3703 mL | 3.4258 mL | |
| 50 mM | 0.1096 mL | 0.5481 mL | 1.0963 mL | 2.7406 mL | |
| 60 mM | 0.0914 mL | 0.4568 mL | 0.9135 mL | 2.2839 mL | |
| 80 mM | 0.0685 mL | 0.3426 mL | 0.6852 mL | 1.7129 mL | |
| 100 mM | 0.0548 mL | 0.2741 mL | 0.5481 mL | 1.3703 mL |
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