113527-49-4
113527-49-4
Chemical Structure
Dansyl-Tyr-Val-Gly
- CAS. Nr.: 113527-49-4
- Formula:C28H34N4O7S
- Molecular Weight:570.66
IUPAC Name: ((5-(dimethylamino)naphthalen-1-yl)sulfonyl)-L-tyrosyl-L-valylglycine
InChIKey: VVDJIPURODAIDY-NVQXNPDNSA-N
SMILES: OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](C(C)C)C(NCC(O)=O)=O)=O)NS(=O)(C2=CC=CC3=C2C=CC=C3N(C)C)=O
Biological Activity: Dansyl-Tyr-Val-Gly is a substrate of peptidylglycine monooxygenase (PHM), with a KD of 22 μM for PHM. Dansyl-Tyr-Val-Gly can be used to investigate the catalytic mechanism, kinetics and inactivation characteristics of PHM[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Dansyl-Tyr-Val-Gly | 99.53% | Dansyl-Tyr-Val-Gly is a substrate of peptidylglycine monooxygenase (PHM), with a KD of 22 μM for PHM. Dansyl-Tyr-Val-Gly can be used to investigate the catalytic mechanism, kinetics and inactivation characteristics of PHM. | ||||||||||||||||||||
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References
- [1]. Welch EF, et al. Pre-Steady-State Reactivity of Peptidylglycine Monooxygenase Implicates Ascorbate in Substrate Triggering of the Active Conformer. Biochemistry. 2022;61(8):665-677. [Content Brief]
- [2]. Merkler DJ, et al. Selective inactivation of the hydroxylase activity of bifunctional rat peptidylglycine alpha-amidating enzyme. Arch Biochem Biophys. 1992;294(2):594-602. [Content Brief]
