Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
53 Results for "
succinyl-
" in MedChemExpress (MCE) Product Catalog:
Products (53)
53 Results for "succinyl-" in MCE Product Catalog:
14
14 Publications Verification
5
5 Cited Publications
Synonyms: succinyl-CoA sodium
Category:
Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
2
2 Cited Publications
Cat. No.: HY-N15971
CAS No.: 1445723-73-8
1
1 Cited Publications
Synonyms: N6-succinyl adenosine
Target:
Research Areas:
Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency .
Cat. No.: HY-173527
Target:
Research Areas:
PSSI-51 is an orally active, peripherally selective inhibitor of succinyl-CoA:3-ketoacid-CoA transferase (SCOT). PSSI-51 inhibits SCOT activity in peripheral tissues (such as muscle and kidney) but does not affect SCOT activity in brain tissue. PSSI-51 reduces ketone body oxidation by inhibiting SCOT, thereby improving obesity-related hyperglycemia. PSSI-51 can be used in the study of type 2 diabetes (T2D) and has the potential to improve obesity-related metabolic disorders .
Synonyms: succinyl-coenzyme A; S-(Hydrogen succinyl)coenzyme A
Target:
Target:
Synonyms: Isosuccinyl coenzyme A tetralithium; Methylmalonyl coenzyme tetralithium
Category:
Human Gut Microbiota Metabolites Natural Products Other Diseases Endogenous metabolite Disease Research Fields
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
Succinyl-CoA synthetase is a mitochondrial matrix enzyme and catalyst. Succinyl-CoA synthetase supports TCA, ketone and heme metabolism and is activated by mitochondrial phosphate. Succinyl-CoA synthetase distributes broadly across mammalian tissues with distinct substrate-related biochemical features. Succinyl-CoA synthetase gains structural stability after phosphorylation and relies on SUCLG1-encoded subunit for activity. Succinyl-CoA synthetase malfunction links to metabolic and neurological disorders. Succinyl-CoA synthetase serves as a research tool for mitochondrial hepatoencephalomyopathy .
Cat. No.: HY-12688
CAS No.: 26647-82-5
Cat. No.: HY-W800793
CAS No.: 186800-61-3
Synonyms: 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)
16:0 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two palmitic acid tails.
Target:
Research Areas:
2'-O-Succinyl-cAMP is a cAMP analog that can be covalently coupled to acetylcholinesterase. 2'-O-Succinyl-cAMP conjugate has been used as tracers in a classical heterogeneous competitive enzyme immunoassay allowing the determination of cAMP .
Cat. No.: HY-P2648
CAS No.: 70968-04-6
Synonyms: N-succinyl-AAPL-p-nitroanilide
Target:
Research Areas:
Cat. No.: HY-P3791
CAS No.: 133525-12-9
Target:
Research Areas:
Cat. No.: HY-160578
CAS No.: 1257309-90-2
Synonyms: N-Cholesteryl succinyl glucosamine
Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate, and can be used in the formation of lipid nanoparticles (LNPs) .
Cat. No.: HY-W973644
CAS No.: 147104-27-6
Target:
Research Areas:
LY-266500 is a succinyl CoA synthetase (SCS) specific inhibitor. LY-266500 has inhibitory effects on various parasites, such as Trypanosoma brucei brucei (IC50 =0.6 μM) and Leishmania donovani (IC50 =2.86 μM). LY-266500 can be used for research on parasitic infections .
Cat. No.: HY-CE00006
Synonyms: (1-Methylpentyl)succinyl-coenzyme A
Target:
Research Areas:
(1-Methylpentyl)succinyl-CoA ((1-Methylpentyl)succinyl-coenzyme A) is a a higher alkylsuccinyl-CoA .
Cat. No.: HY-154857
CAS No.: 89947-80-8
Research Areas:
1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine is a glycerophosphorylcholine, consisting of glycerol phosphate, choline and palmitic acid. It accumulates in vivo at sites of oxidative stress. 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine may be a ligand of scavenger receptors class B, while oxidized phospholipids oxPC(CD36) are potent ligands of scavenger receptors class B (CD36 and SR-BI). Oxidized phospholipids (oxPLs) also play an important role in tumor apoptosis, may be elevated in malignant biliary strictures .
Cat. No.: HY-17664
CAS No.: 192047-93-1
Synonyms: 2’-Sulfo-NHS-succinyl-paclitaxel
Target:
Research Areas:
Paclitaxel succinate sulfo-NHS ester is a derivative of Paclitaxel (HY-B0015). Paclitaxel succinate sulfo-NHS ester can be used for the research of cancer .
Cat. No.: HY-148285A
CAS No.: 403982-65-0
Synonyms: succinyl-coenzyme A disodium; S-(Hydrogen succinyl)coenzyme A disodium
Target:
Research Areas:
Succinyl CoA (Succinyl-coenzyme A) disodium is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA disodium is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA disodium acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA disodium insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl-Coenzyme A sodium can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
