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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
thromboembolic disorders
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "thromboembolic disorders" in MCE Product Catalog:
Target:
Research Areas:
AZD1283 is a potent P2Y12 receptor antagonist with a binding IC50 of 11 nM and a GTPγS IC50 of 25 nM. AZD1283 has excellent antiplatelet aggregation potency. AZD1283 can be used to research thromboembolic disorders .
Cat. No.: HY-10273
CAS No.: 433937-93-0
Synonyms: AZD0837; Atecegatran fexenetil
Target:
Research Areas:
Atecegatran metoxil is a oral anticoagulant, which inhibits thrombin factor II and is used in thromboembolic disorders. In vivo, Atecegatran metoxil is converted to AR-H067637, a selective and reversible direct thrombin inhibitor.
Cat. No.: HY-150519
CAS No.: 1551460-43-5
Target:
Research Areas:
FXIa/Plasma kallikrein-IN-1 is an inhibitor of coagulation factor XIa (FXIa) and plasma kallikrein with Ki values of 187.70 nM and 151.6 nM, respectively. FXIa/Plasma kallikrein-IN-1 can be used in the research of thromboembolic diseases .
Cat. No.: HY-111755
CAS No.: 2299200-91-0
Target:
Research Areas:
P2Y12 antagonist 2 is a potent P2Y12 receptor antagonist. P2Y12 antagonist 2 exhibits excellent antiplatelet aggregation potency with an IC50 value of 2.94 μM as well as antithrombotic efficacy in a rat ferric chloride model. P2Y12 antagonist 2 shows a superior safety profile than Clopidogrel (HY-15283) in a rat tail-bleeding model. P2Y12 antagonist 2 can be used to research thromboembolic disorders .
Cat. No.: HY-W012869
CAS No.: 611-20-1
Target:
Research Areas:
2-Hydroxybenzonitrile is a biochemical reagent. It serves as a precursor for compounds associated with thromboembolic diseases and for reagents that regulate anti-tumor cytotoxicity .
Cat. No.: HY-14878
CAS No.: 917904-13-3
Synonyms: (2R)-AZD-0837
Target:
Research Areas:
(2R)-Atecegatran ((2R)-AZD-0837; (Ph(3-Cl)(5-OCHF2)-(R)CH(OH)C(O)-Aze-Pab)) is a thrombin inhibitor. (2R)-Atecegatran can be used in research related to thromboembolic disorders .
Cat. No.: HY-10281
CAS No.: 209187-02-0
Target:
Research Areas:
YM-60828 methanesulfonate is an orally active, selective and competitive factor Xa inhibitor with a Ki of 1.3 nM and an IC50 of 2.3 nM. YM-60828 methanesulfonate inhibits thrombus formation and platelet aggregation. YM-60828 methanesulfonate can be used for the research of venous thrombosis, arterial thrombosis, and thromboembolic disorders .
Cat. No.: HY-10758
CAS No.: 441328-10-5
Target:
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FXa-IN-1 is a FXa inhibitor (IC50: 3 nM, Ki: 0.7 nM) with respectable oral bioavailability and half-life in vivo. FXa-IN-1 can be used for thromboembolic disorders .
Cat. No.: HY-10275
CAS No.: 433937-74-7
Synonyms: AR-H067637
Target:
Research Areas:
Atecegatran (AR-H067637) is an orally active competitive thrombin inhibitor with a Ki of 2-4 nM. AR-H067637 inhibits platelet activation and aggregation by blocking thrombin binding to fibrin and thrombomodulin. Atecegatran demonstrates significant anticoagulant effects in various plasma coagulation assays, with an IC50 ranging from 93 to 220 nM. Atecegatran can be used in research related to thromboembolic disorders .
Cat. No.: HY-10279
CAS No.: 179755-65-8
Target:
Research Areas:
YM-60828 hydrochloride is an orally active, selective and competitive factor Xa inhibitor with a Ki of 1.3 nM and an IC50 of 2.3 nM. YM-60828 hydrochloride inhibits thrombus formation and platelet aggregation. YM-60828 hydrochloride can be used for the research of venous thrombosis, arterial thrombosis, and thromboembolic disorders .
Cat. No.: HY-10280S
CAS No.: 1794812-00-2
Cat. No.: HY-W706725
CAS No.: 2733842-09-4
Research Areas:
2-Hydroxybenzonitrile-d4 is the deuterated-labeled 2-Hydroxybenzonitrile (HY-W012869). 2-Hydroxybenzonitrile is a biochemical reagent. It serves as a precursor for compounds associated with thromboembolic diseases and for reagents that regulate anti-tumor cytotoxicity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
