1551460-43-5
1551460-43-5
Chemical Structure
FXIa/Plasma kallikrein-IN-1
- CAS No.: 1551460-43-5
- Formula:C31H29ClF2N4O4
- Molecular Weight:595.04
IUPAC Name: 2-chloro-1-(4-ethynylphenyl)ethan-1-one
InChIKey: AXXYATYQRMPQSN-WGDIFIGCSA-N
SMILES: COC(NC1=CC=C(C2=CC([C@@H](CCC[C@H](C3=O)C)N(CCC(C4=C(C=CC(Cl)=C4F)F)=C5)C5=O)=NC=C2)C(N3)=C1)=O
Biological Activity: FXIa/Plasma kallikrein-IN-1 is an inhibitor of coagulation factor XIa (FXIa) and plasma kallikrein with Ki values of 187.70 nM and 151.6 nM, respectively. FXIa/Plasma kallikrein-IN-1 can be used in the research of thromboembolic diseases[1].
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FXIa/Plasma kallikrein-IN-1 | FXIa/Plasma kallikrein-IN-1 is an inhibitor of coagulation factor XIa (FXIa) and plasma kallikrein with Ki values of 187.70 nM and 151.6 nM, respectively. FXIa/Plasma kallikrein-IN-1 can be used in the research of thromboembolic diseases. | |||||||||||||||||||||
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References
Keywords
