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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
vasorelaxant activity
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "vasorelaxant activity" in MCE Product Catalog:
8
Category:
Coumarins Phenylpropanoids Plants Compositae Disease Research Fields Artemisia capillaris Thunb. Cancer
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2
Category:
Cardiovascular Disease Flavonols Flavonoids Croton tiglium Linn. Phenols Polyphenols Euphorbiaceae Plants Disease Research Fields
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1
Category:
Natural Products Labiatae Metabolic Disease Plants Stuhlmannia moavi Taub. Disease Research Fields
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Kaempferia galanga L. Microorganisms Other Phenylpropanoids Phenylpropanoids Plants Zingiberaceae
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Cat. No.: HY-P2619
CAS No.: 30505-63-6
Research Areas:
Cat. No.: HY-W103372
CAS No.: 53242-88-9
Target:
Research Areas:
Vasorelaxant agent-2 (Compound 8h) targets α1A-adrenergic receptor with an affinity of pD2=5.4. Vasorelaxant agent-2 exhibits vasodilator activity in rats aortic rings with an EC50 of 0.79 μM .
Cat. No.: HY-101661
CAS No.: 158001-76-4
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Win 58237 is a cyclic nucleotide phosphodiesterase (PDE) inhibitor, with Ki of 170 nM for PDE V, possessing vasorelaxant activity.
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Cat. No.: HY-138166S
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Cat. No.: HY-138166R
CAS No.: 503610-43-3
Research Areas:
Rosuvastatin lactone (Standard) is the analytical standard of Rosuvastatin lactone. This product is intended for research and analytical applications. Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A), a statin lipid-lowering agent and HMG-CoA inhibitor. Rosuvastatin lactone exhibits endothelium-independent and HMG-CoA reductase-independent vasorelaxant activity in rat aortic rings, and its vasorelaxant effect is jointly mediated by NO produced by inducible nitric oxide synthase (iNOS) located in vascular smooth muscle and activation of potassium channels. Rosuvastatin lactone itself has no lipid-lowering effect .
Cat. No.: HY-Y0121S1
CAS No.: 1336882-58-6
Cat. No.: HY-W047432
CAS No.: 90348-29-1
Synonyms: DL0805
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Research Areas:
5-Nitro-1H-indazole-3-carbonitrile (DL0805) is a Rho kinase(ROCK) inhibitor with an IC50 of 6.67 μM for ROCK-I. 5-Nitro-1H-indazole-3-carbonitrile reduces Norepinephrine (HY-13715)-induced transient contraction and inhibits contraction induced by increasing external calcium in the endothelium-denuded rings of rat models. 5-Nitro-1H-indazole-3-carbonitrile has a vasorelaxant activity but high toxicity. 5-Nitro-1H-indazole-3-carbonitrile can be used for cardiovascular diseases, especially hypertension research .
Cat. No.: HY-N9206
CAS No.: 1872403-23-0
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Cat. No.: HY-170392
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Research Areas:
Vasorelaxant agent-1 (Compound 2j) is a BBB-penetrable vasodilator. Vasorelaxant agent-1 has excellent vasodilator activity with an EC50 of 0.02916 μM. Vasorelaxant agent-1 is non-carcinogenic and can be used in the study of hypertension .
Cat. No.: HY-W750238
CAS No.: 2732916-33-3
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
