53242-88-9
53242-88-9
Chemical Structure
Vasorelaxant agent-2
- CAS No.: 53242-88-9
- Formula:C15H11ClN2O
- Molecular Weight:270.71
IUPAC Name: 4-(4-chlorobenzyl)phthalazin-1(2H)-one
InChIKey: NLXGCQIEVZYDRS-UHFFFAOYSA-N
SMILES: O=C1NN=C(CC2=CC=C(Cl)C=C2)C3=C1C=CC=C3
Biological Activity: Vasorelaxant agent-2 (Compound 8h) targets α1A-adrenergic receptor with an affinity of pD2=5.4. Vasorelaxant agent-2 exhibits vasodilator activity in rats aortic rings with an EC50 of 0.79 μM[1].
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Vasorelaxant agent-2 | Vasorelaxant agent-2 (Compound 8h) targets α1A-adrenergic receptor with an affinity of pD2=5.4. Vasorelaxant agent-2 exhibits vasodilator activity in rats aortic rings with an EC50 of 0.79 μM. | |||||||||||||||||||||
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References
Keywords
