1. Phenylpropanoids
  2. Scoparone

Scoparone 

Cat. No.: HY-N0228 Purity: >98.0%
Handling Instructions

Scoparone is isolated from Artemisia capillaris, has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities.

For research use only. We do not sell to patients.

Scoparone Chemical Structure

Scoparone Chemical Structure

CAS No. : 120-08-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 80 In-stock
Estimated Time of Arrival: December 31
20 mg USD 140 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Scoparone is isolated from Artemisia capillaris, has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1].

In Vitro

Scoparone (0-0.4 nM; 24-48 hours) produces the most inhibition on PSC proliferation at 0.4 nM[1].

In Vivo

Scoparone (oral administration; 30 mg/kg, 60 mg/kg; 4 weeks) greatly ameliorates the pancreatic weight loss induced by DBTC in pancreatitis rats[1].

Animal Model: Chronic Pancreatitis (CP) Rat Models[1]
Dosage: 30 mg/kg, 60 mg/kg
Administration: Oral administration; 30 mg/kg, 60 mg/kg; 4 weeks
Result: Protected against pancreatic damage
Molecular Weight

206.19

Formula

C₁₁H₁₀O₄

CAS No.

120-08-1

SMILES

O=C1C=CC2=CC(OC)=C(OC)C=C2O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (303.12 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8499 mL 24.2495 mL 48.4990 mL
5 mM 0.9700 mL 4.8499 mL 9.6998 mL
10 mM 0.4850 mL 2.4249 mL 4.8499 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (10.09 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (10.09 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (10.09 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

ScoparoneOthersInhibitorinhibitorinhibit

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Scoparone
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HY-N0228
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