21 Results for "

zona

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "zona" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-113313
CAS No.: 52-39-1
Purity:  98.93%
Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level .
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1 Cited Publications
Cat. No.: HY-D0791
CAS No.: 95197-95-8
Synonyms: 5(6)-Tetramethylrhodamine isothiocyanate
TRITC (5(6)-Tetramethylrhodamine isothiocyanate) is a commonly used fluorescent dye, belonging to the Rhodamine derivative family. It exhibits red fluorescence properties (Ex/Em ≈ 550/580 nm). TRITC can be used for cell labeling and imaging .
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1 Cited Publications
Cat. No.: HY-P83694
Synonyms: ZO1_HUMAN; Tight junction protein ZO-1; TJP1; ZO1; Tight junction protein 1; zona occludens protein 1; Zonula occludens protein 1; ZO1 tight junction protein;

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat, Monkey

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Cat. No.: HY-113313S1
Purity:  99.78%
Aldosterone-d7 is the deuterium labeled Aldosterone. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level .
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Cat. No.: HY-103322
CAS No.: 1135306-29-4
Target:  

PKA Potassium Channel

Research Areas:  

Metabolic Disease Cancer

6-Bnz-cAMP sodium, a derivative of cyclic adenosine monophosphate (cAMP), is a selective PKA activator with inhibitory activity against the bTREK-1 K + channel. 6-Bnz-cAMP sodium does not activate the Epac signaling pathway. It inhibits the bTREK-1 K + channel via a voltage-independent, ATP-dependent mechanism that is independent of the PKA/Epac/calmodulin kinase/MAP kinase pathway. 6-Bnz-cAMP sodium activates CREB phosphorylation to regulate osteoblast-specific gene expression, induces osteoblast differentiation, promotes extracellular matrix mineralization, supports osteoblast proliferation, and shows no cytotoxicity toward osteoblasts. It can be used in studies related to bone tissue repair and regeneration .
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Cat. No.: HY-17657
CAS No.: 131211-33-1
Synonyms: 5-Androstenediol 3-sulfate sodium
Androst-5-enediol sulfate (5-Androstenediol 3-sulfate) sodium salt is an adrenal Δ5-steroid sulfate that synthesized by zona reticularis of adrenal depending on the lyase and Cytochrome b5 type A (CYB5A) activity. Androst-5-enediol sulfate sodium salt is a precursor hormone and can be desulfated to produce more potent androgens, including testosterone, in peripheral tissues like skin and liver. The serum level of Androst-5-enediol sulfate sodium salt has an age-related increase .
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Cat. No.: HY-113313S
CAS No.: 1261254-31-2
Purity:  99.8%
Aldosterone-d8 is a deuterium labeled Aldosterone. Aldosterone, produced in the adrenal zona glomerulosa, regulates blood pressure .
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Cat. No.: HY-113313R
CAS No.: 52-39-1
Aldosterone (Standard) is the analytical standard of Aldosterone. This product is intended for research and analytical applications. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level .
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Cat. No.: HY-P11738
CAS No.: 152439-29-7
Target:  

Peptides

Research Areas:  

Endocrinology

Murine ZP3 peptide (330-342) is a zona pellucida 3 polypeptide fragment with the amino acid sequence NSSSSQFQIHGPR. Murine ZP3 peptide (330-342) induces autoimmune premature ovarian failure (POF). Murine ZP3 peptide (330-342) can be used for the research of premature ovarian failure .
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Cat. No.: HY-P10046
CAS No.: 64158-84-5
Target:  

Vasopressin Receptor

Research Areas:  

Metabolic Disease

[Deamino-Pen1,Val4,D-Arg8]-vasopressin (AVP-A) is an arginine-vasopressin (AVP) antagonist. AVP-A can significantly lower plasma aldosterone concentration in rats. AVP-A can be used for the research of the growth and steroidogenic capacity of rat adrenal zona glomerulosa .
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Cat. No.: HY-P3803
CAS No.: 81039-85-2
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

[D-Pro4,D-Trp7,9] Substance P (4-11) is a potent antagonist of Substance P (HY-P0201). [D-Pro4,D-Trp7,9] Substance P (4-11) decreases plasma aldosterone (ALDO) concentration .
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Cat. No.: HY-P71672
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ZP3; ZP3-424; Prev. ZP3A; Zp-3; Prev. ZP3B; zona Pellucida Glycoprotein 3A (Sperm Receptor); ZPC; zona Pellucida Glycoprotein ZP3; zona Pellucida Sperm-Binding Protein 3; zona Pellucida Glycoprotein 3B; zona Pellucida Protein C; OZEMA3; Sperm Receptor; OO
Species:  
Source:  
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Cat. No.: HY-183482
CAS No.: 77862-94-3
Target:  

Dopamine Transporter

Research Areas:  

Neurological Disease

GBR 13098 is a dopamine transporter inhibitor with a rat IC50 of 43 nM, and exhibits dopaminergic activity in vivo .GBR 13098 selectively blocks dopamine uptake, increasing synaptic dopamine availability, with weaker activity against norepinephrine uptake .GBR 13098 induces ipsilateral circling in lesioned rats and increases locomotor activity in naive mice and habituated rats, with effects attenuated by dopamine receptor antagonism .GBR 13098 reduces DOPA formation in dopamine-rich brain regions and enhances inhibitory responses of substantia nigra zona compacta dopamine neurons to dopamine .GBR 13098 serves as a tool for studying dopaminergic systems .
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Cat. No.: HY-P810164
Synonyms: X104, ZO2, TJP2, Tight junction protein ZO-2, Tight junction protein 2, zona occludens protein 2, Zonula occludens protein 2

Host:  

Mouse

Application:  

WB, ICC/IF, IF-Tissue, ELISA

Reactivity:  

human

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Cat. No.: HY-P71669
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PAEP; PP14 Protein (Placental Protein 14); Progestagen Associated Endometrial Protein; zona-Binding Inhibitory Factor-1; Glycodelin; Alpha Uterine Protein; PP14; Placental Protein 14; PAEG; Glycodelin-A; GD; Glycodelin-S; Progesterone-Associated Endometri
Species:  
Source:  
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Cat. No.: HY-P700004
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PAEP; PP14 Protein (Placental Protein 14); Progestagen Associated Endometrial Protein; zona-Binding Inhibitory Factor-1; Glycodelin; Alpha Uterine Protein; PP14; Placental Protein 14; PAEG; Glycodelin-A; GD; Glycodelin-S; Progesterone-Associated Endometri
Species:  
Source:  
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Cat. No.: HY-P703871
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PAEP; PP14 Protein (Placental Protein 14); Progestagen Associated Endometrial Protein; zona-Binding Inhibitory Factor-1; Glycodelin; Alpha Uterine Protein; PP14; Placental Protein 14; PAEG; Glycodelin-A; GD; Glycodelin-S; Progesterone-Associated Endometri
Species:  
Source:  
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Cat. No.: HY-P704068
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PAEP; PP14 Protein (Placental Protein 14); Progestagen Associated Endometrial Protein; zona-Binding Inhibitory Factor-1; Glycodelin; Alpha Uterine Protein; PP14; Placental Protein 14; PAEG; Glycodelin-A; GD; Glycodelin-S; Progesterone-Associated Endometri
Species:  
Source:  
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Cat. No.: HY-P702292
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PAEP; PP14 Protein (Placental Protein 14); Progestagen Associated Endometrial Protein; zona-Binding Inhibitory Factor-1; Glycodelin; Alpha Uterine Protein; PP14; Placental Protein 14; PAEG; Glycodelin-A; GD; Glycodelin-S; Progesterone-Associated Endometri
Species:  
Source:  
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Cat. No.: HY-155940
CAS No.: 41941-66-6
Synonyms: 8CPT-cAMP
Target:  

SGK PKA

Research Areas:  

Metabolic Disease

8-(4-Chlorophenylthio)-cAMP (8CPT-cAMP) is a cell membrane-permeable cAMP analog with excellent membrane permeability, which activates Sgk kinase via phosphorylation mediated by PKA. 8-(4-Chlorophenylthio)-cAMP is hydrolyzed by intracellular enzymes to produce the active metabolite 8CPT-Ade, which induces cortisol synthesis and the expression of steroidogenic protein genes. When used in combination with insulin, 8-(4-Chlorophenylthio)-cAMP enhances the activation of Sgk; it activates the cAMP pathway to promote the proliferation and iodine uptake of thyroid cells. 8-(4-Chlorophenylthio)-cAMP can be used in studies related to metabolism and signal transduction .
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