1. Anti-infection
  2. HIV
  3. Sennoside A

Sennoside A 

Cat. No.: HY-N0365 Purity: 99.71%
Handling Instructions

Sennoside A is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia). Sennoside A is a HIV-1 inhibitor effective on HIV-1 replication.

For research use only. We do not sell to patients.

Sennoside A Chemical Structure

Sennoside A Chemical Structure

CAS No. : 81-27-6

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Description

Sennoside A is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia)[1]. Sennoside A is a HIV-1 inhibitor effective on HIV-1 replication[2].

Molecular Weight

862.74

Formula

C₄₂H₃₈O₂₀

CAS No.

81-27-6

SMILES

OC1C(O)C(OC2=C(C(C(C(O)=CC(C(O)=O)=C3)=C3C4C5C(C=CC=C6OC7C(O)C(O)C(O)C(CO)O7)=C6C(C8=C5C=C(C(O)=O)C=C8O)=O)=O)C4=CC=C2)OC(CO)C1O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (144.89 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1591 mL 5.7955 mL 11.5910 mL
5 mM 0.2318 mL 1.1591 mL 2.3182 mL
10 mM 0.1159 mL 0.5795 mL 1.1591 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (2.41 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Sennoside A
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HY-N0365
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