2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Setosusin

Setosusin ((+)-Setosusin) is a fungal meroditerpenoid featuring a unique spiro-fused 3(2H)-furanone moiety.

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Setosusin

Setosusin 화학구조

CAS No. : 182926-45-0

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Setosusin Related Antibodies

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제품 설명

Setosusin ((+)-Setosusin) is a fungal meroditerpenoid featuring a unique spiro-fused 3(2H)-furanone moiety[1].

IC50 & Target[1]

Microbial Metabolite

 

Cellular Effect
Cell Line Type Value Description References
PC-12 EC50
112.6 μM
Compound: 10
Inhibition of amyloid beta (25 to 35 residues) (unknown origin) aggregate-induced toxicity in rat PC12 cells preincubated for 1 hr followed by amyloid beta challenge measured after 24 hrs by MTT assay
Inhibition of amyloid beta (25 to 35 residues) (unknown origin) aggregate-induced toxicity in rat PC12 cells preincubated for 1 hr followed by amyloid beta challenge measured after 24 hrs by MTT assay
[PMID: 26517152]
분자량

514.61

화학식

C29H38O8
CAS No.
SMILES

CC(C)(O1)[C@]2([C@@](C)([C@@]3([C@@](C)(CC2)[C@@]4(C(C)=CC3)C[C@]5(C(O4)=O)C(C(C)=C(O5)C)=O)[H])[C@H](CC1=O)OC(C)=O)[H]
Structure Classification
Initial Source

ascomycete
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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Setosusin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Setosusin182926-45-0(+)-SetosusinEndogenous Metabolitefungal meroditerpenoidInhibitorinhibitorinhibit

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상품명:
Setosusin
Cat. No.:
HY-119697
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