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  5. Ligustrazine hydrochloride

Ligustrazine hydrochloride  (Synonyms: Chuanxiongzine hydrochloride; Tetramethylpyrazine hydrochloride)

Cat. No.: HY-N0935 Purity: 99.92%
COA Handling Instructions

Ligustrazine (hydrochloride) is a natural product.

For research use only. We do not sell to patients.

Ligustrazine hydrochloride Chemical Structure

Ligustrazine hydrochloride Chemical Structure

CAS No. : 76494-51-4

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Customer Review

Based on 5 publication(s) in Google Scholar

Other Forms of Ligustrazine hydrochloride:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

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Description

Ligustrazine (hydrochloride) is a natural product. IC50 value: Target: In vitro: Ligustrazine hydrochloride displayed a protection effect on injured ECV304 cells, NOS and NO formation were significantly increased compared with the model group [1]. In vivo:

Clinical Trial
Formula

C8H12N2.xHCl

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C1(C)=NC(C)=C(C)N=C1C.C

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic)

H2O : 100 mg/mL (Need ultrasonic)

In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (Infinity mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (Infinity mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (Infinity mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (Infinity mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Ligustrazine hydrochloride
Cat. No.:
HY-N0935
Quantity:
MCE Japan Authorized Agent: