1. Apoptosis
  2. c-Myc

Mivebresib (Synonyms: ABBV-075; ABBV075; ABBV 075)

Cat. No.: HY-100015 Purity: 99.28%
Data Sheet SDS Handling Instructions

Mivebresib, a novel BET family inhibitor, disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo.

For research use only. We do not sell to patients.
Mivebresib Chemical Structure

Mivebresib Chemical Structure

CAS No. : 1445993-26-9

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $101 In-stock
2 mg $80 In-stock
5 mg $100 In-stock
10 mg $150 In-stock
25 mg $250 In-stock
50 mg $450 In-stock
100 mg $750 In-stock
200 mg   Get quote  
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Description

Mivebresib, a novel BET family inhibitor, disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo. Also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins target: BET, MYC In vitro: Mivebresib inhibit DHT-stimulated transcription of AR target genes without significant effect on AR protein expression. In addition to blocking the transcription activation downstream of AR, Mivebresib is also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins.

References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.1764 mL 10.8821 mL 21.7642 mL
5 mM 0.4353 mL 2.1764 mL 4.3528 mL
10 mM 0.2176 mL 1.0882 mL 2.1764 mL
References
M.Wt

459.47

Formula

C₂₂H₁₉F₂N₃O₄S

CAS No.

1445993-26-9

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 37 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Mivebresib
Cat. No.:
HY-100015
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