Angiotensin Receptor
Angiotensin receptors are a class of G protein-coupled receptors with angiotensin II as their ligands. They are important in the renin-angiotensin system: they are responsible for the signal transduction of the vasoconstricting stimulus of the main effector hormone, angiotensin II. The AT1 and AT2 receptors have a similar affinity for angiotensin II, which is their main ligand. The AT1 receptor is the best elucidated angiotensin receptor. AT2 receptors are more plentiful in the fetus and neonate. Other poorly characterized subtypes include the AT3 and AT4 receptors.
Angiotensin Receptor Isoform Specific Products
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Angiotensin Receptor Inhibitors
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Angiotensin Receptor Agonists
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Angiotensin Receptor Antagonists
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Angiotensin Receptor Activators
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Angiotensin Receptor Modulators
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Angiotensin Receptor Chemicals
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Angiotensin Receptor Ligands
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Angiotensin Receptor Related Products (297)
Related Products (297)
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Antibodies (7)
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Angiotensin Receptor Isoform Comparison
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Valsartan-d3
0 ImagesCat. No.: HY-18204S1CAS No.: 1331908-02-1Synonyms: CGP 48933-d3Valsartan-d3 is the deuterium labeled Valsartan. Valsartan (CGP 48933) is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research.
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SL910102
0 ImagesCat. No.: HY-100292CAS No.: 144756-71-8SL910102 is a nonpeptide angiotensin AT1 receptor antagonist.
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Azilsartan mepixetil
0 ImagesSynonyms: QR-01019Azilsartan mepixetil is the antagonist of angiotensin II receptor. Azilsartan mepixetil has stronger and longer blood pressure effect, more abvious and longer lasting heart rate lowering effect and high safety. Azilsartan mepixetil achieves ideal protective effect for heart and kidney functions. Azilsartan mepixetil has the potential for the research of hypertension, chronic heart failure and diabetic nephropathy (extracted from patent CN107400122A).
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Azilsartan mopivabil
0 ImagesAzilsartan mopivabil is the potent antagonist of angiotensin II receptor.
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Olodanrigan sodium
0 ImagesCat. No.: HY-13106ACAS No.: 1316755-17-5Synonyms: EMA401 sodium; PD-126055 sodiumOlodanrigan (EMA401) sodium is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. Olodanrigan sodium is under development as a neuropathic pain therapeutic agent. Olodanrigan sodium analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.
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Irbesartan hydrochloride
0 ImagesCat. No.: HY-B0202ACAS No.: 329055-23-4Synonyms: SR-47436 hydrochloride; BMS-186295 hydrochlorideIrbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease.
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Eprosartan-d3
0 ImagesCat. No.: HY-117743SCAS No.: 1185243-70-2Eprosartan-d3 is the deuterium labeled Eprosartan. Eprosartan (SKF-108566J free base) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan binds angiotensin II receptor with IC50s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively .
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Renin FRET Substrate I
0 ImagesCat. No.: HY-P2492CAS No.: 142988-22-5Renin FRET Substrate I is a substrate of human renin. Renin FRET Substrate I is designed to incorporate the renin cleavage site that occurs in the N-terminal peptide of human angiotensinogen.
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Losartan-d3 Carboxylic Acid
0 ImagesCat. No.: HY-17512S1CAS No.: 1189729-40-5Losartan-d3 Carboxylic Acid is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
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[Sar1, Ile8]-Angiotensin II
![[Sar1, Ile8]-Angiotensin II](https://file.medchemexpress.com/product_pic/hy-p1564.gif "Click to View [Sar1, Ile8]-Angiotensin II Product Detail")
0 ImagesCat. No.: HY-P1564CAS No.: 37827-06-8[Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.
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Ripisartan
0 ImagesCat. No.: HY-119544CAS No.: 148504-51-2Synonyms: UP-2696Ripisartan (UP-2696) is an angiotensin II receptor antagonist. Ripisartan is orally available. Ripisartan binds to angiotensin II receptors, dilates blood vessels, and lowers blood pressure.
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Tonlamarsen sodium
0 ImagesCat. No.: HY-147406ACAS No.: 2589926-21-4Synonyms: ION-904 sodiumTonlamarsen (ION-904) sodium is a GalNAc-conjugated antisense oligonucleotide and Angiotensinogen synthesis inhibitor. Tonlamarsen sodium specifically reduces the production of Angiotensinogen in the liver and plasma, and exhibits extremely low activity in the kidneys. Tonlamarsen sodium can be used in research related to hypertension and heart failure.
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AT2R antagonist 1
0 ImagesCat. No.: HY-146410CAS No.: 2709031-17-2AT2R antagonist 1 (compound 21) is a potent and high selective AT2R (angiotensin II AT2 receptor) ligand. AT2R antagonist 1 exhibits a fair AT2R affinity, with a Ki of 29 nM. AT2R antagonist 1 also inhibits common agent-metabolizing CYP enzymes. AT2R antagonist 1 shows high stability in human, rat and mouse liver microsomes.
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(Sar1,Gly8)-Angiotensin II
0 ImagesCat. No.: HY-P11389CAS No.: 51887-62-8(Sar1,Gly8)-Angiotensin II is an AT1 angiotensin II receptor subtype selective antagonist (Ki: 52 nM for AT2 receptor in rat adrenal). (Sar1,Gly8)-Angiotensin II potently antagonizes dipsogenic responses to intracerebroventricularly administered Ang II.
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Evazarsen
0 ImagesCat. No.: HY-147267CAS No.: 2589926-22-5Synonyms: ISIS-757456Evazarsen is an angiotensinogen synthesis inhibitor and possesses antihypertensive properties.
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CR 3834
0 ImagesCat. No.: HY-105298CAS No.: 868741-81-5CR 3834 is a angiotensin-AT1 antagonist. CR 3834 can be used for the research of cardiovascular disease.
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CI-996
0 ImagesCat. No.: HY-19165CAS No.: 150438-02-1CI-996 is a potent, selective, orally active angiotensin II (Ang II) type 1 (AT1) receptor antagonist. In rat liver membranes CI-996 displaces specifically bind [125I]Ang II with an IC50 of 0.8 nM. CI-996 has blood pressure-lowering activity.
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Angiotensin II (1-4), human TFA
0 ImagesCat. No.: HY-P1792AAngiotensin II (1-4), human (TFA) is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney.
