Angiotensin Receptor
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Angiotensin Receptor Related Products (213)
Related Products (213)
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Sodium nitroprusside
0 ImagesSynonyms: Ro 21-2498Sodium nitroprusside (Ro 21-2498) is a potent vasodilator working through releasing NO spontaneously in blood.
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Sacubitril/Valsartan
0 ImagesSynonyms: LCZ696Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure. Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis.
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Irbesartan
0 ImagesSynonyms: SR-47436; BMS-186295Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease.
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AAA
0 ImagesCat. No.: HY-160187Purity: 99.52%AAA is an orally active 20-HETE receptor antagonist. AAA exerts antihypertensive and organoprotective effects. AAA blocks 20-HETE prohypertensive actions, suppresses intrarenal and circulating angiotensin II levels, and interferes with renin-angiotensin system interactions. AAA attenuates development of, and reverses established, ANG II (HY-13948)-dependent malignant hypertension. AAA reduces albuminuria, glomerulosclerosis, and cardiac hypertrophy linked to malignant hypertension. AAA can be used for the research of malignant hypertension.
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Nepitrin
0 ImagesNepitrin (Nepetin-7-glucoside) is an orally active bradykinin and angiotensin antagonist isolated from Scrophularia striata. Nepitrin antagonizes the spasmogenic effects of Bradykinin and Angiotensin, thereby inhibiting inflammatory mediator pathways. Nepitrin is applicable to arthritis-related research.
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trans-Tranilast
0 ImagesSynonyms: trans-MK-341; trans-SB 252218
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Losartan potassium (Standard)
0 ImagesSynonyms: DuP-753 potassium (Standard)Losartan (potassium) (Standard) is the analytical standard of Losartan (potassium). This product is intended for research and analytical applications. Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC50 of 20 nM.
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YS-49
0 ImagesYS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II)-stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors.
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Sparsentan
0 ImagesSynonyms: RE-021; DARA-aSparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively.
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AVE 0991
0 ImagesAVE 0991 is a nonpeptide and orally active angiotensin-(1-7) receptor agonist with an IC50 of 21 nM.
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Losartan Carboxylic Acid
0 ImagesSynonyms: E-3174; EXP-3174Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure.
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Saralasin TFA
0 ImagesSynonyms: [Sar1,Ala8] Angiotensin II TFASaralasin ([Sar1,Ala8] Angiotensin II) TFA is an octapeptide analog of angiotensin II. Saralasin TFA is a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Saralasin TFA can be used for the research of renovascular hypertension, renin-dependent (angiotensinogenic) hypertension.
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Abz-Gly-p-nitro-Phe-Pro-OH
0 ImagesAbz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths.
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Angiotensin II human, FAM-labeled
0 ImagesCat. No.: HY-13948F1Purity: 99.58%Synonyms: Angiotensin II, FAM-labeled ; Ang II, FAM-labeled ; DRVYIHPF, FAM-labeledAngiotensin II human, FAM-labeled (Angiotensin II, FAM-labeled) is a FAM labeled Angiotensin II human (HY-13948).
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Saralasin
0 ImagesSynonyms: [Sar1,Ala8] Angiotensin IISaralasin ([Sar1,Ala8] Angiotensin II) is an octapeptide analog of angiotensin II. Saralasin is a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Saralasin can be used for the research of renovascular hypertension, renin-dependent (angiotensinogenic) hypertension.
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Eprosartan
0 ImagesSynonyms: SKF-108566J free baseEprosartan (SKF-108566J free base) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan binds angiotensin II receptor with IC50s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively .
