1176306-10-7
Chemical Structure
Alamandine
- CAS No.: 1176306-10-7
- Formula:C40H62N12O9
- Molecular Weight:855.00
InChIKey: QVMYBFKDLPBYSO-GIGALADGSA-N
SMILES: CC[C@H](C)[C@@H](C(N[C@@H](CC1=CN=CN1)C(N2CCC[C@H]2C(O)=O)=O)=O)NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](C)N)=O)=O)=O)=O
Biological Activity: Alamandine, a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Alamandine targets to protect the kidney and heart through anti-hypertensive actions[1][2].
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Alamandine | 99.90% | Alamandine, a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Alamandine targets to protect the kidney and heart through anti-hypertensive actions. | ||||||||||||||||||||
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- [1]. Daniel C Villela, et al. Alamandine: a new member of the angiotensin family. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):130-4. [Content Brief]
- [2]. Johanna Schleifenbaum. Alamandine and Its Receptor MrgD Pair Up to Join the Protective Arm of the Renin-Angiotensin System. Front Med (Lausanne). 2019 Jun 11;6:107. [Content Brief]
Keywords