569-90-4
Chemical Structure
Nepitrin
Synonym(s): Nepetin-7-glucoside
- CAS No.: 569-90-4
- Formula:C22H22O12
- Molecular Weight:478.40
IUPAC Name: 2-(3,4-dihydroxyphenyl)-5-hydroxy-6-methoxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
InChIKey: DMXHXBGUNHLMQO-IWLDQSELSA-N
SMILES: O=C1C=C(C2=CC=C(O)C(O)=C2)OC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=C(OC)C(O)=C13
Biological Activity: Nepitrin (Nepetin-7-glucoside) is an orally active bradykinin and angiotensin antagonist isolated from Scrophularia striata. Nepitrin antagonizes the spasmogenic effects of Bradykinin and Angiotensin, thereby inhibiting inflammatory mediator pathways. Nepitrin is applicable to arthritis-related research[1][2].
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Nepitrin | 99.36% | Nepitrin (Nepetin-7-glucoside) is an orally active bradykinin and angiotensin antagonist isolated from Scrophularia striata. Nepitrin antagonizes the spasmogenic effects of Bradykinin and Angiotensin, thereby inhibiting inflammatory mediator pathways. Nepitrin is applicable to arthritis-related research. | ||||||||||||||||||||
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Nepitrin (Standard) | ≥98% | Nepitrin (Standard) (Nepetin-7-glucoside (Standard)) is the analytical standard of Nepitrin (HY-N5010). This product is intended for research and analytical applications. Nepitrin (Nepetin-7-glucoside) is an orally active bradykinin and angiotensin antagonist isolated from Scrophularia striata. Nepitrin antagonizes the spasmogenic effects of Bradykinin and Angiotensin, thereby inhibiting inflammatory mediator pathways. Nepitrin is applicable to arthritis-related research. | ||||||||||||||||||||
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References
- [1]. Safavi F, et al. Phytochemical Composition and Acute Hypoglycemic Effect of Jefea lantanifolia (S. Schauer) Strother in Rats. Plants (Basel). 2025 Oct 2;14(19):3054.
- [2]. Agarwal OP, et al. The anti-inflammatory action of nepitrin, a flavonoid. Agents and actions. 1982 Jul;12(3):298-302. [Content Brief]
