Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2504)
Related Products (2504)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Antimalarial agent 53
0 ImagesCat. No.: HY-179118Antimalarial agent 53 (compound 31) is an antimalarial agent. Antimalarial agent 53 blocks protein synthesis by inhibiting the cytoplasmic ribosomes of malaria parasites, exhibiting potent antimalarial activity (IC50 = 3.9 nM) and good selectivity. Antimalarial agent 53 has no cross resistance and good safety. Antimalarial agent 53 can be used for research on malaria.
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Menoctone
0 ImagesCat. No.: HY-167647CAS No.: 14561-42-3Menoctone is an orally active antimalarial agent that demonstrates suppressive effects against blood-induced rodent malaria. Menoctone enhances the anti-malarias effect of chloroquine or quinine and can be utilized in malarias research.
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Antitrypanosomal agent 30
0 ImagesCat. No.: HY-181508CAS No.: 3113099-14-9Antitrypanosomal agent 30 (compound 6b) is a trypanocidal agent with extremely low cytotoxicity against mouse macrophages. Antitrypanosomal agent 30 can be used for the research of Chagas disease.
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Sitamaquine hydrochloride
0 ImagesSitamaquine (WR6026) hydrochloride, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine hydrochloride inhibits mitochondrial complex II (succinate dehydrogenase). Sitamaquine hydrochloride is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes.
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Milbemycin A3 Oxime
0 ImagesCat. No.: HY-118357CAS No.: 114177-14-9Milbemycin A3 Oxime is a macrocyclic lactone antiparasitic agent that exhibits potent inhibitory activity against Dirofilaria immitis.
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Desethyl chloroquine diphosphate (Standard)
0 ImagesDesethyl chloroquine (diphosphate) (Standard) is the analytical standard of Desethyl chloroquine (diphosphate). This product is intended for research and analytical applications. Desethyl chloroquine diphosphate is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine diphosphate possesses antiplasmodic activity.
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Dapsone-15N2
0 ImagesCat. No.: HY-B0688S3CAS No.: 287476-19-1Synonyms: 4,4′-Diaminodiphenyl sulfone-15N2; DDS-15N2Dapsone-15N2 (4,4′-Diaminodiphenyl sulfone-15N2) is 15N labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al.
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Erioflorin
0 ImagesCat. No.: HY-187654CAS No.: 27542-17-2Erioflorin is a sesquiterpene lactone compound originally isolated from plants of the Asteraceae family (such as Eriophyllum confertiflorum and species of the Podanthus genus). Erioflorin acts as a selective β-TrCP1 modulator. Erioflorin induces cell apoptosis by increasing intracellular reactive oxygen species (ROS) production and decreasing mitochondrial membrane potential, inhibits the NF-κB signaling pathway by blocking the phosphorylation of IκBα, and prevents the ubiquitination and degradation of the tumor suppressor Pdcd4 by inhibiting the interaction between Pdcd4 and the E3 ubiquitin ligase β-TrCP1. Erioflorin can be used in research related to breast cancer, colon cancer, advanced prostate cancer, and Chagas disease.
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Eprinomectin B1a
0 ImagesCat. No.: HY-N8483CAS No.: 133305-88-1
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Chalcone (Standard)
0 ImagesSynonyms: (E/Z)-Benzylideneacetophenone (Standard)Chalcone (Standard) is the analytical standard of Chalcone. This product is intended for research and analytical applications. Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities.
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2,6-Dibromophenol (Standard)
0 Images2,6-Dibromophenol (2,6-DBP) is a weak inhibitor targeting voltage-gated Ca2+ channels. 2,6-Dibromophenol has no significant effect on potassium-induced calcium elevation in PC12 cells. 2,6-Dibromophenol shows a 48 h EC50 of 2.78 mg/L for Daphnia magna and a 96 h EC50 of 9.90 mg/L for algae (Scenedesmus quadricauda).
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(Rac)-ACT-451840
0 ImagesCat. No.: HY-111817ACAS No.: 1839508-99-4(Rac)-ACT-451840 is an isomer of ACT-451840 that exhibits significant antimalarial effects. (Rac)-ACT-451840 exhibits significant antimalarial activity against P. berghei-infected mice at a dose of 20 mg/kg (ED90=13 mg/kg), and has an inhibitory effect at a dose of 300 mg/kg. The ED90 of (Rac)-ACT-451840 in the P. falciparum humanized immunodeficient mouse model is 3.7 mg/kg. (Rac)-ACT-451840 is similar to artemisinin, with a rapid onset of action but requires repeated high doses.
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Artemether (Standard)
0 ImagesSynonyms: Dihydroqinghaosu methyl ether (Standard); Dihydroartemisinin methyl ether (Standard); SM224 (Standard)Artemether (Standard) is the analytical standard of Artemether. This product is intended for research and analytical applications. Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria.
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Aurachin B
0 ImagesCat. No.: HY-118288CAS No.: 108354-12-7Aurachin B is an alkaloid with a 3-hydroxyquinoline N-oxide core.
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Trimetrexate (Standard)
0 ImagesCat. No.: HY-10373RCAS No.: 52128-35-5Synonyms: CI-898 (Standard)Trimetrexate (Standard) is the analytical standard of Trimetrexate (HY-10373). This product is intended for research and analytical applications. Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer.
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Primaquine (Standard)
0 ImagesCat. No.: HY-12651ARCAS No.: 90-34-6Primaquine (Standard) is the analytical standard of Primaquine. This product is intended for research and analytical applications. Primaquine is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine prevents relapse in vivax and ovale malaria.
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(E/Z)-N-p-trans-Coumaroyltyramine
0 ImagesCat. No.: HY-N2230ACAS No.: 20375-37-5(E/Z)-N-p-trans-Coumaroyltyramine is an amide. (E/Z)-N-p-trans-Coumaroyltyramine is present in the leaves of Annona muricata L. (E/Z)-N-p-trans-Coumaroyltyramine exhibits certain brine shrimp larvicidal activity.
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Dapsone (Standard)
0 ImagesSynonyms: 4,4′-Diaminodiphenyl sulfone (Standard); DDS (Standard)Dapsone (Standard) is the analytical standard of Dapsone. This product is intended for research and analytical applications. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al.
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Ascaridole (Standard)
0 ImagesAscaridole (Standard) is the analytical standard of Ascaridole. This product is intended for research and analytical applications. Ascaridole is an anthelmintic and also has antimalarial activity.
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Artefenomel (Standard)
0 ImagesSynonyms: OZ439 (Standard)Artefenomel (Standard) is the analytical standard of Artefenomel. This product is intended for research and analytical applications. Artefenomel (OZ439) is an orally active, synthetic anti-malarial compound containing an artemisinin pharmacophore with a mechanism of action similar to that of artemisinin. Artefenomel has antiviral activity against SARS-CoV-2.
