608-33-3
608-33-3
Chemical Structure
2,6-Dibromophenol
- CAS No.: 608-33-3
- Formula:C6H4Br2O
- Molecular Weight:251.91
IUPAC Name: 2,6-dibromophenol
InChIKey: SSIZLKDLDKIHEV-UHFFFAOYSA-N
SMILES: OC1=C(Br)C=CC=C1Br
Biological Activity: 2,6-Dibromophenol (2,6-DBP) is a weak inhibitor targeting voltage-gated Ca2+ channels. 2,6-Dibromophenol has no significant effect on potassium-induced calcium elevation in PC12 cells. 2,6-Dibromophenol shows a 48 h EC50 of 2.78 mg/L for Daphnia magna and a 96 h EC50 of 9.90 mg/L for algae (Scenedesmus quadricauda)[1][2].
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2,6-Dibromophenol | 99.76% | 2,6-Dibromophenol (2,6-DBP) is a weak inhibitor targeting voltage-gated Ca2+ channels. 2,6-Dibromophenol has no significant effect on potassium-induced calcium elevation in PC12 cells. 2,6-Dibromophenol shows a 48 h EC50 of 2.78 mg/L for Daphnia magna and a 96 h EC50 of 9.90 mg/L for algae (Scenedesmus quadricauda). | ||||||||||||||||||||
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2,6-Dibromophenol (Standard) | ≥98% | 2,6-Dibromophenol (2,6-DBP) is a weak inhibitor targeting voltage-gated Ca2+ channels. 2,6-Dibromophenol has no significant effect on potassium-induced calcium elevation in PC12 cells. 2,6-Dibromophenol shows a 48 h EC50 of 2.78 mg/L for Daphnia magna and a 96 h EC50 of 9.90 mg/L for algae (Scenedesmus quadricauda). | ||||||||||||||||||||
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2,6-Dibromophenol-d3 | 99.6% | 2,6-Dibromophenol-d3 is the deuterium labeled 2,6-Dibromophenol. 2,6-Dibromophenol is an endogenous metabolite. | ||||||||||||||||||||
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References
- [1]. Hassenklöver T, et al. Bromophenols, both present in marine organisms and in industrial flame retardants, disturb cellular Ca2+ signaling in neuroendocrine cells (PC12). Aquat Toxicol. 2006 Jan 5;76(1):37-45. [Content Brief]
- [2]. Li B, et al. Acute Toxicities of Bromophenols to Alga and Daphina: Comparative Species Sensitivity Distribution Between Standard and Dietary Supplementation Tests. J Toxicol. 2025 May 11;2025:3399746. [Content Brief]
