3-Aminobenzene-1,2-diol
Based on 1 Customer Validation
3-Aminobenzene-1,2-diol (compound C8) is a matrix metalloproteinase (MMP) inhibitor with IC50 values of 20, 26, 16 and 16.3 μM for MMP-2, MMP-8, MMP-9 and MMP-14, respectively.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 20734-66-1
- Formula: C6H7NO2
- Molecular Weight:125.13
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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MMP-2 20 μM (IC50) |
MMP-8 26 μM (IC50) |
MMP-9 16 μM (IC50) |
MMP-14 16.3 μM (IC50) |
Chemical Information
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CAS No. 20734-66-1
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Appearance Solid
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Molecular Weight 125.13
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Formula C6H7NO2
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Color Light brown to brown
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SMILES
OC1=CC=CC(N)=C1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (199.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.9917 mL | 39.9584 mL | 79.9169 mL | 199.7922 mL |
| 5 mM | 1.5983 mL | 7.9917 mL | 15.9834 mL | 39.9584 mL | |
| 10 mM | 0.7992 mL | 3.9958 mL | 7.9917 mL | 19.9792 mL | |
| 15 mM | 0.5328 mL | 2.6639 mL | 5.3278 mL | 13.3195 mL | |
| 20 mM | 0.3996 mL | 1.9979 mL | 3.9958 mL | 9.9896 mL | |
| 25 mM | 0.3197 mL | 1.5983 mL | 3.1967 mL | 7.9917 mL | |
| 30 mM | 0.2664 mL | 1.3319 mL | 2.6639 mL | 6.6597 mL | |
| 40 mM | 0.1998 mL | 0.9990 mL | 1.9979 mL | 4.9948 mL | |
| 50 mM | 0.1598 mL | 0.7992 mL | 1.5983 mL | 3.9958 mL | |
| 60 mM | 0.1332 mL | 0.6660 mL | 1.3319 mL | 3.3299 mL | |
| 80 mM | 0.0999 mL | 0.4995 mL | 0.9990 mL | 2.4974 mL | |
| 100 mM | 0.0799 mL | 0.3996 mL | 0.7992 mL | 1.9979 mL |