2. Signaling Pathways
  3. Epigenetics
  4. DNA Glycosylase
  5. DNA Glycosylase Activator

DNA Glycosylase Activator

DNA Glycosylase Activator (1):

Cat. No. Product Name Effect Purity
  • HY-179014
    OGG1 activator-1
    		Activator
    OGG1 activator-1 (Compound 30) is a selective 8-oxoguanine DNA glycosylase-1 (OGG1) activator with an AC50 value of 0.58 μM. OGG1 activator-1 does not activate nor inhibit the key downstream repair enzyme APE1, and shows > 150-fold selectivity for the activation effect on OGG1. OGG1 activator-1 exhibits extremely high metabolic stability and almost no cytotoxicity. OGG1 activator-1 can be used for the study of oxidative stress-related diseases (such as neurodegenerative diseases, fibrotic diseases, cancer, inflammation, etc.).