GHR

Growth Hormone Receptor; Somatotropin Receptor; Growth Hormone Binding Protein (GHBP)

Growth hormone (GH), also known as somatotropin, promotes body growth by binding with two GH receptors (GHRs) at the cell surface. GHRs interact with Janus kinase, signal transducers, and transcription activators to stimulate metabolic effects and insulin-like growth factor (IGF) synthesis. However, process dysfunctions in the GH–GHR–IGF-1 axis cause animal dwarfism. If, during the GH process, GHR is not successfully recognized and/or bound, or GHR fails to transmit the GH signal to IGF-1, the GH dysfunction occurs.

GHR 관련 제품 (28):

By Effects:	Inhibitors (7) Agonists (2) Ligand (1) Antagonists (2) Activators (5)

Cat. No.	상품명	효과	Purity	Chemical Structure

HY-P990966

Redalsomatropin alfa
Redalsomatropin alfa (JR-142) is a recombinant long-acting growth hormone. Redalsomatropin alfa extends its half-life through fusion with modified serum albumin. Redalsomatropin alfa is well-tolerated and can maintain IGF-1 levels. Redalsomatropin alfa can be used in research related to growth hormone deficiency.

HY-RS16752

Ghrh Mouse Pre-designed siRNA Set A
Ghrh Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ghrh gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-P99924

Efpegsomatropin	Agonist
Efpegsomatropin is a long-acting human growth hormone-Fc conjugate. Efpegsomatropin is applicable for biochemical research.

HY-164419B

Atesidorsen sodium scrambled negative control	Inhibitor
Atesidorsen sodium scrambled negative control is the sequence scrambled negative control of Atesidorsen sodium.

HY-19305

EP-51216
EP-51216 is a growth hormone agonist peptide. EP-51216 increases food intake. EP-51216 can be used in the research of eating disorders.

HY-180210

Ghrelin receptor full agonist-3
Ghrelin receptor full agonist-3 (Compound 22) is a selective, potent and orally active ghrelin receptor full agonist with an EC₅₀ of 1.8 nM. Ghrelin receptor full agonist-3 can stimulate pulsatile secretion of growth hormone (GH), significantly increasing the frequency and duration of GH secretion, thereby inducing a sustained increase in insulin-like growth factor-1 (IGF-1) levels. Ghrelin receptor full agonist-3 can be used for the researches of cancer and chronic obstructive pulmonary disease.

HY-P990721

Inpegsomatropin
Inpegsomatropin is a pegylated long-acting recombinant human growth hormone.

HY-153934

Tetrazole-C15-(N-acetylsulfamoyl)butanoic acid	Ligand
Tetrazole-C15-(N-acetylsulfamoyl)butanoic acid (Ligand 1) improves the pharmacokinetic properties of therapeutic peptides and proteins through non-covalent binding with human serum albumin (HSA). Tetrazole-C15-(N-acetylsulfamoyl)butanoic acid can be used for synthesis of long-acting human growth hormone (HGH) analog somapacitan.

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