2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Glutathione Reductase (GR)
  5. Glutathione Reductase (GR) Inhibitor

Glutathione Reductase (GR) Inhibitor

Glutathione Reductase (GR) Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-B1820
    Zinc sulphate
    		Inhibitor 99.85%
    Zinc sulphate is an orally active inhibitor of tyrosinase and glutathione reductase. Zinc sulphate enhances the activity of dopachrome tautomerase. Zinc sulphate delays anagen-related eumelanin production, induces hair hypopigmentation in mice, and accelerates wound healing. Zinc sulphate can be used in research related to benign gastric ulcers. Zinc sulphate can be used in research related to rheumatoid arthritis.
  • HY-12542S
    Dantrolene-13C3
    		Inhibitor 99.0%
    Dantrolene-13C3 is the 13C3 labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.
  • HY-Y0590
    Copper(I) oxide
    		Inhibitor
    Copper (I) oxide is an oxidative stress inducer and cytotoxic agent. Copper (I) oxide causes dose-dependent decrease in the viability of airway epithelial cells by impairing the activities of catalase and glutathione reductase, generating reactive oxygen species, and increasing the levels of 8-isoprostane and the ratio of oxidized glutathione. However, when combined with Resveratrol (HY-16561), the cytotoxic effect induced by Copper (I) oxide is significantly attenuated, and oxidative damage is effectively alleviated.