2. Others Metabolic Enzyme/Protease
  3. Biochemical Assay Reagents Tyrosinase Environmental Pollutants Glutathione Reductase (GR)
  4. Zinc sulphate

Zinc sulphate is an orally active inhibitor of tyrosinase and glutathione reductase. Zinc sulphate enhances the activity of dopachrome tautomerase. Zinc sulphate delays anagen-related eumelanin production, induces hair hypopigmentation in mice, and accelerates wound healing. Zinc sulphate can be used in research related to benign gastric ulcers. Zinc sulphate can be used in research related to rheumatoid arthritis.

For research use only. We do not sell to patients.

CAS No. : 7733-02-0

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in Water In-stock
Solid
25 g In-stock
50 g In-stock
100 g In-stock
> 100 g   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Zinc sulphate Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Zinc sulphate

Cell Proliferation/Viability Assay

    Zinc sulphate purchased from MedChemExpress. Usage Cited in: Int Immunopharmacol. 2026 Jan 1;168(Pt 1):115768.  [Abstract]

    Viability assays demonstrating TPEN cytoprotection and ZnSO4 (Zinc sulphate; 115 μM; 24 h) -aggravated injury in colistin-exposed HK-2 cells.

    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    Zinc sulphate is an orally active inhibitor of tyrosinase and glutathione reductase. Zinc sulphate enhances the activity of dopachrome tautomerase. Zinc sulphate delays anagen-related eumelanin production, induces hair hypopigmentation in mice, and accelerates wound healing. Zinc sulphate can be used in research related to benign gastric ulcers. Zinc sulphate can be used in research related to rheumatoid arthritis[1][2][3].

    In Vitro

    Zinc inhibits tyrosinase and glutathione reductase in vitro, but also enhances the activity of dopachrome tautomerase and acts as an agonist of melanocortin receptor signaling[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Zinc sulphate Related Antibodies
    In Vivo

    Zinc sulphate (20 mg/mL; administered orally via drinking water; continuous; up to 11 months) induces a persistent lightening of hair shafts to a bright brown color during the natural anagen phase of mouse hair, inhibits eumelanin production without switching to pheomelanin production, and reduces the density of melanin granules in hair follicle structures[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: C57BL/6 a/a (female, 6-8 weeks old)[1]
    Dosage: 20 mg/mL
    Administration: oral; continuous; up to 11 months
    Result: Observed macroscopic bright brown lightening of new hair shafts produced during anagen, with the effect maintained throughout the treatment period.
    Confirmed no switch from eumelanogenesis to phaeomelanogenesis via EPR analysis.
    Reduced and poorly pigmented melanin granules in precortical hair matrix keratinocytes, hair bulb melanocytes, and hair shafts compared with controls.
    Maintained hair coat lightening usually persisted until the immediately consecutive anagen phase after treatment discontinuation.
    Clinical Trial
    Molecular Weight

    161.44

    Formula

    ZnSO4
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O=S(=O)=[Zn](=O)=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Store at room temperature, keep dry and cool

    In solvent -80°C 1 year
    -20°C 6 months
    Solvent & Solubility
    In Vitro: 

    H2O : 50 mg/mL (309.71 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 6.1943 mL 30.9713 mL 61.9425 mL
    5 mM 1.2389 mL 6.1943 mL 12.3885 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 99.85%

    SDS (620 KB)

    COA (250 KB)

    Handling Instructions (2659 KB)
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 6.1943 mL 30.9713 mL 61.9425 mL 154.8563 mL
    5 mM 1.2389 mL 6.1943 mL 12.3885 mL 30.9713 mL
    10 mM 0.6194 mL 3.0971 mL 6.1943 mL 15.4856 mL
    15 mM 0.4130 mL 2.0648 mL 4.1295 mL 10.3238 mL
    20 mM 0.3097 mL 1.5486 mL 3.0971 mL 7.7428 mL
    25 mM 0.2478 mL 1.2389 mL 2.4777 mL 6.1943 mL
    30 mM 0.2065 mL 1.0324 mL 2.0648 mL 5.1619 mL
    40 mM 0.1549 mL 0.7743 mL 1.5486 mL 3.8714 mL
    50 mM 0.1239 mL 0.6194 mL 1.2389 mL 3.0971 mL
    60 mM 0.1032 mL 0.5162 mL 1.0324 mL 2.5809 mL
    80 mM 0.0774 mL 0.3871 mL 0.7743 mL 1.9357 mL
    100 mM 0.0619 mL 0.3097 mL 0.6194 mL 1.5486 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • No file chosen (Maximum size is: 1024 Kb)
    • If you have published this work, please enter the PubMed ID.
    • Your name will appear on the site.

    Zinc sulphate Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Zinc sulphate7733-02-0Biochemical Assay ReagentsTyrosinaseEnvironmental PollutantsGlutathione Reductase (GR)Environmental ContaminantsGlutathione Reductaseeumelanogenesismelanocortin receptor 1hair follicle cyclingtyrosinaseglutathione reductaserheumatoid arthritisCu,Zn-superoxide dismutasedopachrome tautomerasebenign gastric ulcersmelanocortin receptor 4Inhibitorinhibitorinhibit

    Your Recently Viewed Products:

    Inquiry Online

    Your information is safe with us. * Required Fields.

    Product Name

    		  

    Requested Quantity *

    Applicant Name *

    		 

    Salutation

    Email Address *

    		 

    Phone Number *

    Department

    		 

    Organization Name *

    City

    State

    Country or Region *

    		      

    Remarks

    Bulk Inquiry

    Inquiry Information

    Product Name:
    Zinc sulphate
    Cat. No.:
    HY-B1820
    Quantity:
    MCE Japan Authorized Agent:

    Customer Review

    Thank You for Your Feedback!

    Request for HNMR Report

    Please fill out this form to request the QC report. We will send it to your Email address shortly.

    Your information is safe with us. * Required Fields.

    Product Name

    		  

    Lot #

    Applicant Name *

    		 

    Email Address *

    Phone Number

    		 

    Department *

    Organization Name *

    		 

    Country or Region *

    Remarks

    SAFETY DATA SHEET (SDS)

    English - EN (620 KB) Français - FR (620 KB) Deutsch - DE (620 KB) Norwegian - NO (620 KB) Español - ES (620 KB) Swedish - SV (620 KB) Italian - IT (620 KB) Korean - KR (620 KB) Portuguese - PT (620 KB)

    Request for HNMR Report

    We have received your request and will respond to you as soon as possible.