Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
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Reference Standards Related Products (11491)
Related Products (11491)
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KI696 isomer (Standard)
0 ImagesCat. No.: HY-101140ARCAS No.: 1799974-69-8KI696 isomer (Standard) is the analytical standard of KI696 isomer (HY-101140A). This product is intended for research and analytical applications. KI696 isomer is an isomer of KI696 (HY-101140). KI696 is a selective KEAP1/NRF2 protein-protein interaction inhibitor with a human Kd value of 1.3 nM. KI696 acts by competitively occupying the NRF2-binding pocket of the KEAP1 Kelch domain. KI696 blocks KEAP1-mediated ubiquitination and degradation of NRF2, promotes the translocation of NRF2 to the nucleus, activates the expression of downstream antioxidant genes, increases intracellular glutathione levels, and alleviates oxidative stress-induced cell damage and inflammatory cell infiltration in the lungs. KI696 reduces ozone-induced pulmonary oxidative damage and inflammatory cell accumulation in rats, and upregulates pulmonary antioxidant genes. KI696 can be used in research related to chronic obstructive pulmonary disease, oxidative stress and inflammation.
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Davunetide (Standard)
0 ImagesCat. No.: HY-105066RCAS No.: 211439-12-2Davunetide (Standard) is the analytical standard of Davunetide (HY-105066). This product is intended for research and analytical applications. Davunetide is an eight amino acid snippet derived from activity-dependent neuroprotective protein (ADNP), a neurotrophic factor that exists in the mammalian CNS. Davunetide possesses neuroprotective, neurotrophic and cognitive protective roperties. Davunetide, a microtubule-stabilizing peptide, interacts with and stabilises neuron-specific βIII-tubulin in vitro. Davunetide penetrates the blood-brain barrier and is non-toxic. Davunetide inhibits Aβ aggregation and Aβ-induced neurotoxicity.
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TTT-28 (Standard)
0 ImagesCat. No.: HY-101511RCAS No.: 1609138-51-3TTT-28 (Standard) is the analytical standard of TTT-28 (HY-101511). This product is intended for research and analytical applications. TTT-28 is a synthesized thiazole-valine peptidomimetic, a novel selective inhibitor of ABCB1 (P-gp/MDR1) with high efficacy and low toxicity, which reverses the ATP-binding cassette sub-family B member 1 (ABCB1)-mediated multidrug resistance (MDR) by selectively blocking the efflux function of ABCB1.
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Glufosfamide (Standard)
0 ImagesCat. No.: HY-16232RCAS No.: 132682-98-5Synonyms: D 19575 (Standard); Glucosylifosfamide mustard (Standard)Glufosfamide (Standard) is the analytical standard of Glufosfamide. This product is intended for research and analytical applications. Glufosfamide is a glucose-conjugated alkylating cytotoxic agent and a derivative of Ifosfamide (HY-17419). Glufosfamide induces apoptosis frequency and increase the expression of caspase-9 and caspase-3 in cancer cells. Glufosfamide shows great anti-tumor activity in MiaPaCa-2-RFP mouse model. Glufosfamide can be used for the study of hepatocellular carcinoma, prostate cancer and pancreatic carcinoma.
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1-Phenylpropane-1,2-dione (Standard)
0 ImagesCat. No.: HY-W018758RCAS No.: 579-07-71-Phenylpropane-1,2-dione, isolated from young Ephedra sinica Stapf (Ephedraceae), is biosynthetic precursors of the ephedrine alkaloids.
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Alisol B 23-acetate (Standard)
0 ImagesSynonyms: 23-Acetylalismol B (Standard); 23-O-Acetylalisol B (Standard); Alisol B monoacetate (Standard)Alisol B 23-acetate (Standard) is the analytical standard of Alisol B 23-acetate (HY-N0805). This product is intended for research and analytical applications. Alisol B 23-acetate is an orally active prototerpane-type triterpenoid. Alisol B 23-acetate can be isolated from Alisma orientalis. Alisol B 23-acetate induces Apoptosis, promotes ROS generation, downregulates CDK4/6, MMP-2/9, upregulates cleaved PARP, activates FXR and inhibits Syk. Alisol B 23-acetate has anti-inflammatory and hepatoprotective activities. Alisol B 23-acetate protects the kidney from ischemia-reperfusion injury. Alisol B 23-acetate has anticancer activity against ovarian cancer, colon cancer, lung cancer, and gastric cancer. Alisol B 23-acetate can be used in the study of atherosclerosis and allergic asthma.
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Quiflapon sodium (Standard)
0 ImagesSynonyms: MK-591 sodium (Standard)Quiflapon (sodium) (Standard) is the analytical standard of Quiflapon (sodium). This product is intended for research and analytical applications. Quiflapon sodium (MK-591 sodium) is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor. Quiflapon sodium is an orally active Leukotriene biosynthesis inhibitor. Induces apoptosis.
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Dihydrorhodamine 123 (Standard)
0 ImagesSynonyms: DHR 123 (Standard)Dihydrorhodamine 123 (Standard) is the analytical standard of Dihydrorhodamine 123 (HY-101894). This product is intended for research and analytical applications. Dihydrorhodamine 123 (DHR 123) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria (Ex/Em = 515/536 nm).
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Moroxydine hydrochloride (Standard)
0 ImagesSynonyms: ABOB hydrochloride (Standard)Moroxydine (ABOB) hydrochloride (Standard) is the analytical standard of Moroxydine (ABOB) hydrochloride (HY-B0420A). Moroxydine (ABOB) hydrochloride is a broad-spectrum agent with multi-antiviral activities against DNA and RNA viruses, including influenza virus, herpes simplex, varicella zoster, measles, mumps disease, hepatitis C virus, etc. Moroxydine hydrochloride exhibits excellent antiviral activity and shows low cytotoxicity to cells infected by dsRNA viruses (grass carp reovirus, GCRV) and large DNA viruses (giant salamander iridovirus, GSIV). Moroxydine hydrochloride blocks the GCRV-induced cytopathic effects and eliminates nucleocapsids in ctenopharyngodon idella kidney (CIK) cells to keep the normal morphological structure. Moroxydine hydrochloride significantly inhibits the apoptosis, the caspase 3 activity, Bax expression and down-regulates Bcl-2 levels.
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Thonzylamine (Standard)
0 ImagesThonzylamine (Standard) is the analytical standard of Thonzylamine. This product is intended for research and analytical applications. Thonzylamine is an orally active H1 histamine receptor antagonist, exhibits good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases.
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Sorafenib impurity 6 (Standard)
0 ImagesCat. No.: HY-W107225RCAS No.: 1209459-88-0Sorafenib impurity 6 (Standard) is the analytical standard of Sorafenib impurity 6 (HY-W107225). This product is intended for research and analytical applications.
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Pseudolaric Acid A (Standard)
0 ImagesCat. No.: HY-N0673RCAS No.: 82508-32-5Pseudolaric Acid A (Standard) is the analytical standard of Pseudolaric Acid A. This product is intended for research and analytical applications. Pseudolaric Acid A is a diterpene acid isolated from Pseudolarix kaempferi, has antifungal, cytotoxic and antifertile activities.
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Pyroxasulfone (Standard)
0 ImagesPyroxasulfone (Standard) is the analytical standard of Pyroxasulfone. This product is intended for research and analytical applications. Pyroxasulfone is a broad-spectrum pyrazole herbicide used primarily for all-season residual weed control in corn and soybeans. Pyroxasulfone is active against a variety of annual grasses and some broad-leaved weeds, and can be absorbed through roots and stems to inhibit early seedling growth of sensitive plants. Pyroxasulfone can be used to study herbicide effects and weed resistance.
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Acoramidis hydrochloride (Standard)
0 ImagesCat. No.: HY-109165ARCAS No.: 2242751-53-5Synonyms: AG10 hydrochloride (Standard)Acoramidis hydrochloride (Standard) is the analytical standard of Acoramidis (hydrochloride) (HY-109165A). This product is intended for research and analytical applications. Acoramidis (AG10) hydrochloride is an orally active and selective Kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) hydrochloride is used in the study for transthyretin amyloidosis.
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Ascr#7 (Standard)
0 ImagesCat. No.: HY-N9441RCAS No.: 1139837-37-8Ascr#7 (Standard) is the analytical standard of Ascr#7 (HY-N9441). This product is intended for research and analytical applications. Ascr#7, an ascaroside, is a hormone of nematodes. Ascr#7 is expressed during nematode development. Ascarosides can induce formation of long-lived and highly stress resistant dauer larvae.
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Telaglenastat (Standard)
0 ImagesSynonyms: CB-839 (Standard)Telaglenastat (Standard) is the analytical standard of Telaglenastat. This product is intended for research and analytical applications. Telaglenastat (CB-839) is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat inuduces autophagy and has antitumor activity.
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Vismodegib (Standard)
0 ImagesSynonyms: GDC-0449 (Standard)Vismodegib (Standard) is the analytical standard of Vismodegib. This product is intended for research and analytical applications. Vismodegib (GDC-0449) is a BBB-permeable and orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively.
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Octaethylene glycol monododecyl ether (Standard)
0 ImagesCat. No.: HY-138941RCAS No.: 3055-98-9Synonyms: C12E8 (Standard)Octaethylene glycol monododecyl ether (Standard) is the analytical standard of Octaethylene glycol monododecyl ether. This product is intended for research and analytical applications. Octaethylene glycol monododecyl ether (C12E8) is an non-ionic detergent that can be used for membrane protein extraction. Octaethylene glycol monododecyl ether can solubilize the viral membrane of intact influenza virus.
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Chlorquinaldol (Standard)
0 ImagesChlorquinaldol (Standard) is the analytical standard of Chlorquinaldol. This product is intended for research and analytical applications. Chlorquinaldol (Chloquinan) is an antibacterial agent with the potential use in topical skin conditions and vaginal infections. Chlorquinaldol is a β-catenin/TCF4 inhibitor, showing anti-proliferation, anti-migration, and apoptosis-inducing activity in cancer cells.
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Demeclocycline (Standard)
0 ImagesCat. No.: HY-121268RCAS No.: 127-33-3Demeclocycline (Standard) is the analytical standard of Demeclocycline (HY-121268). This product is intended for research and analytical applications. Demeclocycline is an orally active tetracycline antibiotic. Demeclocycline impairs protein synthesis by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA. Demeclocycline shows anti-bacterial activitise to a wide variety of bacterial infections.
